Award Data

Military medical personnel are not prepared to provide trauma care to severely injured soldiers in wartime due to inadequate and unrealistic battlefield training opportunities during peacetime. Training has historically been done on human cadavers and live animals, but cadavers are in limited supply, and animal rights groups and physicians are increasing pressure to end the practice of using live ...

The overall objective of the proposed project is to develop new injury criteria, model based risk assessment methodology, and a software tool to assess neck injury risk from head supported mass (HSM) loading. Based on the foundation of Phase I feasibility studies, the proposed Phase II work will focus on model enhancement, extension and validation, risk assessment, and software integration and tes ...

Rapid and accurate characterization and/or identification of the differentiation state of the stem cells is critical to the development of regenerative medicine technologies as well as tissue engineering solutions. Current methods and devices are time-consuming, labor-intensive, costly, invasive, and consequently, ill-suited for deployment in military and other limited resource settings. To overco ...

Current methods to discern the differentiation state of stem cells are time-consuming, labor-intensive, costly, invasive, and consequently, ill-suited for clinical applications. To overcome these limitations, we propose to develop a microfluidic stem cell analyzer for accurate, non-invasive identification of the cell differentiation state in conjunction with automated cell sorting at high-throughp ...

Current methods for stem cell isolation are time-consuming, costly, and labor-intensive, and ill-suited for point of care applications. To overcome these limitations, we propose to develop and demonstrate a high-throughput, non-invasive, microfluidic stem cell analyzer to enable a rapid isolation of high-quality stem cell products from clinically relevant samples. Our technology enables significan ...

Many geospatial technologies and modeling techniques exist, especially for 3-D visualization of correlated layers of data. A gap remains in integrating the unstructured world of voice, chat, and free-form text communications to the more structured world

Tuberculosis (TB) is a re-emerging infectious disease threat worldwide. To protect the health of US military personnel, TB screen is required for military personnel at the time of service entrance. However, current TB screening methods TST and IGRA used in military population have their drawbacks in application such as high false positives and being heavily lab dependent. Here ADA Technologies, ...

Recent research has shown that Superconducting Quantum Interference Devices (SQUIDs) may be used to measure the very weak magnetic signal in Magnetic Resonance Imaging at ultra-low magnetic fields in the milli-tesla range or below. However, the signal-to-noise ratio (SNR) is quite low, requiring very long averaging times to obtain reasonable spatial resolution. The use of large arrays of SQUIDs wo ...

Recent research has shown that Superconducting Quantum Interference Devices (SQUIDs) may be used to measure the very weak magnetic signals in Magnetic Resonance Imaging (MRI) at ultra-low magnetic fields in the milli-tesla range or below. However, the signal-to-noise ratio (SNR) is quite low, requiring very long averaging times to obtain reasonable spatial resolution. Under the Phase I project, we ...

Current toxicity testing of foodstuffs involves mass spectrometry analysis which requires a>24 h turnaround time in deployed military operations. This length of time is dangerous for personnel. Rapid identification of toxic industrial chemicals (TICs) in food using a sensor that is biologically-based and easy to use eliminates that danger and would provide exactly what is needed for toxicity eva ...