Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A Nano-pharmaceutical Platform for Creating Artificial Vaccines

    SBC: PARABON NANOLABS, INC.            Topic: OSD11H01

    In this project, Parabon NanoLabs (PNL) will demonstrate the feasibility of extending its Essemblix(tm) Drug Development Platform, a combination of computer-aided design (CAD) software and DNA nano-fabrication technology, to produce Essemblix-V, a platform for creating artificial vaccines from a predefined set of"building block molecules"assembled on DNA origami. Given an epitope for a potential ...

    SBIR Phase I 2011 Department of DefenseDefense Health Program
  2. A Nano-pharmaceutical Platform for Creating Artificial Vaccines

    SBC: PARABON NANOLABS, INC.            Topic: OSD11H01

    In this project, Parabon NanoLabs will employ its Essemblix(tm) Drug Development Platform, a combination of computer-aided design (CAD) software and DNA nano-fabrication technology, to produce artificial vaccines against the biothreat agent ricin on DNA origami decorated first with natural epitopes and ultimately with artificial epitotopes (hereafter"mimotope") constructed from a predefined set of ...

    SBIR Phase II 2013 Department of DefenseDefense Health Program
  3. A Neck Injury Assessment Tool

    SBC: CFD Research Corporation            Topic: DHP13009

    The overall objective of the proposed project is to develop new injury criteria, model based risk assessment methodology, and a software tool to assess neck injury risk from head supported mass (HSM) loading. Based on the foundation of Phase I feasibility studies, the proposed Phase II work will focus on model enhancement, extension and validation, risk assessment, and software integration and tes ...

    SBIR Phase II 2015 Department of DefenseDefense Health Program
  4. A Point-of-Care Device for Diagnosis of Platelet Injury in Trauma Patients

    SBC: HEMOSONICS            Topic: DHP13013

    HemoSonics LLC is developing an easy to use and easy to interpret diagnostic device to rapidly identify diffuse coagulopathies in order to guide proper and evidence-based interventions. The management of diffuse coagulopathies is extremely important in military medicine as these conditions represent a significant source of combat morbidity and mortality. HemoSonics device is based on sonorheome ...

    SBIR Phase II 2015 Department of DefenseDefense Health Program
  5. A rapid and high-throughput microfluidic stem cell analyzer

    SBC: CFD Research Corporation            Topic: OSD11H14

    Current methods to discern the differentiation state of stem cells are time-consuming, labor-intensive, costly, invasive, and consequently, ill-suited for clinical applications. To overcome these limitations, we propose to develop a microfluidic stem cell analyzer for accurate, non-invasive identification of the cell differentiation state in conjunction with automated cell sorting at high-throughp ...

    SBIR Phase II 2013 Department of DefenseDefense Health Program
  6. A rapid and high-throughput microfluidic stem cell analyzer

    SBC: CFD Research Corporation            Topic: OSD11H14

    Current methods for stem cell isolation are time-consuming, costly, and labor-intensive, and ill-suited for point of care applications. To overcome these limitations, we propose to develop and demonstrate a high-throughput, non-invasive, microfluidic stem cell analyzer to enable a rapid isolation of high-quality stem cell products from clinically relevant samples. Our technology enables significan ...

    SBIR Phase II 2015 Department of DefenseDefense Health Program
  7. Advanced Blood Simulant for Simulation Based Medical Trauma Training

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: OSD10H01

    The aim of this proposal is to develop an advanced blood simulant to replace current simulants used in combat medical training. A successful blood simulant will exhibit a caking/clotting response in the presence of simulated hemostatic agents while accur

    SBIR Phase I 2011 Department of DefenseDefense Health Program
  8. A NANOeSPRi-based IVD Assay for Multiple Organ Injury

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: DHP14005

    Major organ injuries such as liver, kidney, heart and lung injuries can lead to high morbidity and mortality in critically ill patients. Advanced noninvasive testing with high sensitivity and specificity is needed to detect specific organ injury particularly at early stages. Current techniques such as PCR, MS, absorption-based assays, ELISA and microfluidic-Luminex, cannot meet such requirements. ...

    SBIR Phase II 2015 Department of DefenseDefense Health Program
  9. Cultural Logic Understanding Engine (CLUE)

    SBC: DECISIVE ANALYTICS CORPORATION            Topic: OSD10HS1

    Without some way to acquire or access insight into the social dynamics of battlespace populations, Warfighters will operate with a limited or inaccurate understanding of the human terrain and an impeded ability to explain current social behavior and to pr

    SBIR Phase I 2011 Department of DefenseDefense Health Program
  10. Deployed First Responder Course of Action (COA) Evaluation and After Action Review (AAR) Tools

    SBC: AEGIS TECHNOLOGIES GROUP, INC., THE            Topic: OSD10H07

    Many geospatial technologies and modeling techniques exist, especially for 3-D visualization of correlated layers of data. A gap remains in integrating the unstructured world of voice, chat, and free-form text communications to the more structured world

    SBIR Phase I 2011 Department of DefenseDefense Health Program
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