Award Data

Sweat contains biomarkers that give an indication of human cognitive levels. In this SBIR project TDA Research is developing a modular sweat sensor patch that has the capability to not only carry out real-time monitoring of select biomarkers, but also to

Current methods for stem cell isolation are time-consuming, costly, and labor-intensive, and ill-suited for point of care applications. To overcome these limitations, we propose to develop and demonstrate a high-throughput, non-invasive, microfluidic stem cell analyzer to enable a rapid isolation of high-quality stem cell products from clinically relevant samples. Our technology enables significan ...

The vast majority of injuries in recent military conflicts have been inflicted by improvised explosive devices (IEDs) causing brain, extremities and genital-urinary injuries. Advanced computational models of IED blast physics and human body injury biomech

Current methods to discern the differentiation state of stem cells are time-consuming, labor-intensive, costly, invasive, and consequently, ill-suited for clinical applications. To overcome these limitations, we propose to develop a microfluidic stem cell analyzer for accurate, non-invasive identification of the cell differentiation state in conjunction with automated cell sorting at high-throughp ...

The overall objective of the proposed project is to develop new injury criteria, model based risk assessment methodology, and a software tool to assess neck injury risk from head supported mass (HSM) loading. Based on the foundation of Phase I feasibility studies, the proposed Phase II work will focus on model enhancement, extension and validation, risk assessment, and software integration and tes ...

Military personnel must be protected from diseases transmitted by ticks and fleas, including Lyme disease. Effective surveillance of tick and flea vectors is vital to determine the population present, whether they are carrying disease, and whether control campaigns are working. Unfortunately, current surveillance tools are ineffective. In Phase I TDA designed, prototyped, and tested a novel ti ...

Currently, deployed medics are required to transport, maintain and be resupplied with liquid-based medications and materials that are heavy, expensive to transport, perishable and may require refrigeration. Many medications and materials are or will soon

Musculoskeletal injury among military personnel is an under-recognized problem where shoulder injuries are significant and result in inflammation and pain from overuse, joint derangement, sprain/stain/rupture, and dislocation. Health hazard assessment is essential to ensure that fielded equipment and occupational duties do not exceed human capabilities over short and long term exposures. Hazard ...

Veterans with amputations are relatively common as a result of war and peace keeping efforts. The civilian amputee population is also steadily growing as a result of vascular disease. For many years, there has been an emphasis on the development of prosth

Traumatic injuries account for 30% of all life years lost in the US and is the leading cause of death for people under 46 years of age. Uncontrolled bleeding or hemorrhage constitute 30-40% of trauma related deaths and are considered to be a major cause o