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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Novel Trap for Ticks and Fleas Incorporating a CO2 Generator

    SBC: TDA Research, Inc.            Topic: DHP13007

    Military personnel must be protected from diseases transmitted by ticks and fleas, including Lyme disease. Effective surveillance of tick and flea vectors is vital to determine the population present, whether they are carrying disease, and whether control campaigns are working. Unfortunately, current surveillance tools are ineffective. In Phase I TDA designed, prototyped, and tested a novel ti ...

    SBIR Phase II 2015 Department of DefenseDefense Health Program
  2. Novel Rewarming Technique for Cyropreserved Tissue

    SBC: TDA Research, Inc.            Topic: DHP15014

    TDAs proposes to develop a novel RF heating process for rewarming cryogenically preserved tissues and organs. TDAs approach is to optimize the RF frequency and power, along with the chemical composition, size and morphology of infused nanoparticles so that they heat tissue samples rapidly and uniformly. In this manner, the cryoprotectant solutions pass from the vitrified state to the liquid stat ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  3. Rapid Rewarming Reduction of Cryoprotectant Toxicity and Concentration Employing Magnetic Nanoparticles

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: DHP15014

    We will evaluate a novel warming method, developed by our collaborator John Bischof, that promises solution of one of the remaining barriers for banking of large organs and vascularized composite tissues. The method involves radiofrequency and magnetic nanoparticles to obtain rapid uniform electromagnetic rewarming of biological materials instead of warming from the outer boundary using convection ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  4. Avoiding the Ice Cryolesion in Tissue Cryopreservation with Ice Modulators

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: DHP15013

    The long term goal of the proposed research is to develop improved methods for cryopreservation of complex tissues at extreme low temperature. An innovative approach is taken in the proposed line of research, where synthetic ice modulators (SIMs) are combined with established cryoprotective agent (CPA) cocktails to create more favorable conditions for cryopreservation in a process known as vitrifi ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  5. Development of a field-appropriate biosensor for detecting Mycobacterium tuberculosis infection

    SBC: NANORETE, INC.            Topic: OSD11H05

    nanoRETE is a developing a nanoparticle-based biosensor technology platform that has the ability for real-time detection of pathogens. Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis (Mtb) that primarily affects the lungs. In Phase I research, nanoRETE demonstrated proof-of-concept of an electrochemical nano-bead biosensor for measuring plasma cytokine and chemokine concentrati ...

    SBIR Phase II 2013 Department of DefenseDefense Health Program
  6. Novel Vector Survaillance Trap for Flying Insects

    SBC: TDA Research, Inc.            Topic: DHP12007

    Civilian and military organizations throughout the world perform surveillance to combat vector-borne disease. Of particular concern to the U.S. military are mosquito genera Anopheles, Aedes and Culex, which are important vectors for malaria, dengue and West Nile virus respectively, and sand fly genera Phlebotomus and Lutzomyia, both vectors for leishmaniasis. The trap most commonly used for by U.S ...

    SBIR Phase I 2013 Department of DefenseDefense Health Program

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