Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Neuroinformatics platform using machine learning and content-based image retrieval for neuroscience image data

    SBC: MICROBRIGHTFIELD, INC.            Topic: 101

    This project aims to develop NeuroManageran innovative neuroinformatics platform for advanced parsingstoringaggregatinganalyzing and sharing of complex neuroscience image dataA core technology that we will develop in NeuroManager will be Image Content Analysis for Retrieval Using SemanticsICARUSa novelintelligent neuroimage curation system that will enable image retrieval based on visual appearanc ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  2. An Integrated CT-based Image-Guided Neurosurgical System

    SBC: Xoran Technologies LLC            Topic: 102

    An Integrated CT based Image Guided Neurosurgical System In this SBIR Phase IIb proposal Xoran intends to commercialize a compact and affordableyet highlyfunctionalsystem to provide real time image updates and navigation guidance in support of minimally invasive cranial and spinal neurosurgical proceduresThe effort builds on previously developed compact and portable flat panel Computed TomographyC ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Chemo-enzymatic synthesis of nucleotide sugar libraries and therapy-relevant derivatives

    SBC: CHEMILY, LLC            Topic: 300

    Glycans and glycoconjugates are widespread in nature and play pivotal roles in cell cell recognitioncell differentiationand immunological responsesMost glycans and glycosylation reactions require nucleotide sugars as their essential building blocksThereforethe commercial availability of nucleotide sugars will determine future opportunities for carbohydrate based innovationsjust as the availability ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Human Neural Cell Exosomes as a therapeutic treatment for stroke

    SBC: Aruna Biomedical, Inc.            Topic: NINDS

    Project Summary Cytoprotective and restorative treatments for acute ischemic strokeAISis a major unmet medical needThe current standard of care for stroke patients is centered on recanalization efforts to restore cerebral perfusion through the administration of tissue plasminogen activatortPAor mechanical thrombectomyHoweverdespite a recent extension of recanalization treatment windowan estimated ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Microneedle Delivery of Zanamivir for Treatment of Influenza

    SBC: TSRL, INC.            Topic: NIAID

    Abstract Yearly influenza epidemics strike millions of peoplecausing up todeathsFatality caused by most seasonal influenza viruses is andltbut with significant mortality in the young and the elderly populationsWhen a new pathogenic influenza strain enters the populationa pandemic could kill tens of millions of people with a negative economic impact estimated to be overbillion dollarsInfluenza viru ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Chronological Sweat Sensor Patch for Real-Time Human Molecular Biomarker Monitoring

    SBC: TDA Research, Inc.            Topic: DHA18003

    Sweat contains biomarkers that give an indication of human cognitive levels. In this SBIR project TDA Research is developing a modular sweat sensor patch that has the capability to not only carry out real-time monitoring of select biomarkers, but also to collect multiple precisely time stamped chronological samples (50-150 Ls each) for off-line analysis in laboratory assays.In Phase I, we demonstr ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  7. Lightweight, Compact System for Generating Lactated Ringer's Solution

    SBC: TDA Research, Inc.            Topic: DHA172011

    Currently, deployed medics are required to transport, maintain and be resupplied with liquid-based medications and materials that are heavy, expensive to transport, perishable and may require refrigeration.Many medications and materials are or will soon be available in concentrated or dehydrated formularies that require sterile water for injection (SWFI) to rehydrate for immediate use, one of the ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  8. Advanced therapeutic for Parkinson's Disease

    SBC: INHIBIKASE THERAPEUTICS            Topic: 999

    Parkinsonandapos s DiseasePDis a progressive neurodegenerative disorder that affectsmillion patient in the U Sannually andtomillion people worldwidePD is characterized by disorders of movementwhich are caused by the progressive loss of dopamine neurons in the substantia nigra pars compactaSNpcand autonomic dysfunctionanxietydepressionsleep disorders and cognitive impairment that are due to the deg ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Pharmacologic Suppression of Reperfusion Injury Following Endovascular Thrombectomy In Stroke.

    SBC: BIOMIMETIX JV LLC            Topic: 102

    Ischemic stroke is a leading cause of death and disability in the United StatesThis often is attributable to thrombus formation at an atherosclerotic plaque or thromboembolismPatients who present withinhours of symptom onset are eligible for thrombolysis with tissue plasminogen activatortPAThis serves andltof victimsRecentlymajor advance has been made with proven efficacy from endovascular mechani ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Articulating Video Stylet for Improved Intubation Success Rates

    SBC: BRIO DEVICE, LLC            Topic: NHLBI

    Project SummaryMore thanmillion intubations are performed in the US every year and may carry a high rate of procedure related and disease related complicationsThe higher incidence of difficult intubation in children is due to a more anterior larynx and presence of congenital syndromes resulting insuffering complications during and related to airway managementDifficult intubations in pediatric pati ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
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