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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A compact, modular two-photon fiber-coupled microscope for in vivo all-optical electrophysiology
SBC: INTELLIGENT IMAGING INNOVATIONS, INC. Topic: 101Good methods to interrogateand ideally perturbneural systems at the network level have been elusive until recentlyThe advent of biochemical breakthroughsnamely neuronally targeted genetically encoded calcium reporterssuch as GCaMPand light activated channelssuch as channelrhodopsinhave enabledall opticalelectrophysiology where experiments can be conducted that involve simultaneousor closely sequen ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Active Variable-Stiffness Prosthetic Foot
SBC: INTELLIGENT PROSTHETIC SYSTEMS, LLC Topic: NICHDDESCRIPTION provided by applicant The long term goal of this project is to develop prosthetic foot technology that can function differently for different activities Although current prostheses can be very effective for particular tasks e g walking running or standing an amputee must choose a single prosthesis to achieve reasonably good performance across all daily activities This resul ...
SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Addressing Opioid Use Disorder with an External Multimodal Neuromodulation Device: Development and Clinical Evaluation of DuoTherm for Opioid-Sparing in Acute and Chronic Low Back Pain.
SBC: MMJ Labs, LLC Topic: NIDAProject Summary The goal of this project is to develop a multimodal neuromodulatory opioid sparing device for low back paindemonstrate effective pain reliefthen evaluate opioid reduction for patients with acute or chronic back pain presenting for treatmentPain and opioid use disorderOUDare intricately relateddependence begins for up towith medications prescribed for paineither directly or through ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Adenoviral Mediated Gene Therapy for Experimental Glioma
SBC: TSRL, INC. Topic: N/AN/A
SBIR Phase I 1995 Department of Health and Human Services -
A Dietary Supplement As Adjunct Therapy In Castration-Resistant Prostate Cancer
SBC: MetCure Therapeutics LLC Topic: 102DESCRIPTION provided by applicant Castration Resistant Prostate Cancer Castration resistant prostate cancer CRPC directly contributes to patient mortality It is imperative to develop new and effective adjunct therapy to enhance the response of CRPC to hormonal therapy Recently we developed ProFineTM a proprietary formula consisting of bioactive flavonoids enriched in pomegranate fruit and ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Advanced GST Proteomics for Early Stage Organ-Specific Toxicity Screening. Phase
SBC: OXFORD BIOMEDICAL RESEARCH, INC. Topic: NIEHSDESCRIPTION: Biomarkers currently employed for the detection of organ toxicity are often not sensitive enough to detect the early stages of acute organ damage, i.e. at a stage when reducing or eliminating exposure to a toxin could prevent progression of organ damage or a disease process, nor do they adequately discriminate damage to one organ system vs. another. For example, the level of aminotra ...
SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health -
Advanced Nitric Oxide Release Bactericidal Urinary Catheters
SBC: BIOCREDE INC. Topic: NIDDKDESCRIPTION (provided by applicant): We propose a novel and competitive urinary tract silicone Foley catheter made from a proprietary polymeric formulation to effectively reduce catheter-associated urinary tract infections (CAUTI) via nitric oxide (NO) release. Preliminary studies show that the device will be able to: (1) continuously deliver NO at rates enough to maintain bactericidal properties ...
STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health -
Advanced Nitric Oxide Release Bactericidal Urinary Catheters
SBC: BIOCREDE INC. Topic: 300DESCRIPTION provided by applicant In Phase I Biocrede developed a completely new urinary tract silicone Foley catheter with a andgt month shelf life made from a proprietary polymeric formulation to effectively reduce catheter associated urinary tract infections CAUTI via nitric oxide NO release for andgt weeks Key features of the new technology include catheters continuously d ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Advanced therapeutic for Parkinson's Disease
SBC: Inhibikase Therapeutics, Inc. Topic: 999Parkinsonandapos;s Disease (PD) is a progressive neurodegenerative disorder that affects ≈1 million patient in the U.S. annually and 7 to 10 million people worldwide. PD is characterized by disorders of movement, which are caused by the progressive loss of dopamine neurons in the substantia nigra pars compacta (SNpc), and autonomic dysfunction, anxiety, depression, sleep disorders and cognitive ...
SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
A fast, scalable, cost-effective, single-stranded library protocol for cell-free DNA
SBC: Claret Bioscience LLC Topic: 102Project Summary Liquid biopsy is a potentially powerfulnon invasive approach for detectingclassifying and monitoring tumors by capturing cell free DNA molecules found circulating in blood and other bodily fluidsAny next generation sequencingNGSbased approach requires an efficient protocol for converting cell free DNA into a sequencing libraryNearly all currently available NGS library preparation m ...
SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health