Award Data

Sweat contains biomarkers that give an indication of human cognitive levels. In this SBIR project TDA Research is developing a modular sweat sensor patch that has the capability to not only carry out real-time monitoring of select biomarkers, but also to

Currently, deployed medics are required to transport, maintain and be resupplied with liquid-based medications and materials that are heavy, expensive to transport, perishable and may require refrigeration. Many medications and materials are or will soon

Veterans with amputations are relatively common as a result of war and peace keeping efforts. The civilian amputee population is also steadily growing as a result of vascular disease. For many years, there has been an emphasis on the development of prosth

Military personnel must be protected from diseases transmitted by ticks and fleas, including Lyme disease. Effective surveillance of tick and flea vectors is vital to determine the population present, whether they are carrying disease, and whether control campaigns are working. Unfortunately, current surveillance tools are ineffective. In Phase I TDA designed, prototyped, and tested a novel ti ...

TDAs proposes to develop a novel RF heating process for rewarming cryogenically preserved tissues and organs. TDAs approach is to optimize the RF frequency and power, along with the chemical composition, size and morphology of infused nanoparticles so that they heat tissue samples rapidly and uniformly. In this manner, the cryoprotectant solutions pass from the vitrified state to the liquid stat ...

We propose to take our hearing-test device, which was designed to support research in advancing hearing-conservation programs, and ruggedize it for use in theater. Five key challenges that make the commercial-off-the-shelf OAE systems unsuitable for HCPs, will be overcome. We will: 1) implement next-generation otoacoustic emission tests to enable OAE measurements in noise-damaged ears, 2) add smar ...

The technical objective of this Phase 1 proposal is to develop a non-toxic, multi-component, next generation cryostasis cocktail. We seek to develop a unique, holistic and non-toxic approach to bank human organs for several weeks up to a few months. Our approach is based on using the best strategies employed by freeze-tolerant and hibernating animals in nature and then augmenting them with complem ...

Mimosa Acoustics will develop a portable binaural audiological device, based on our successful HearID system. HearID is a clinical system for otoacoustic emission and middle-ear power analysis testing; it is FDA and CE-marked. The new system will have the ability to conduct a variety of audiological tests especially for use in hearing-conservation programs, including: flexible otoacoustic emission ...

nanoRETE is a developing a nanoparticle-based biosensor technology platform that has the ability for real-time detection of pathogens. Tuberculosis (TB) is a disease caused by Mycobacterium tuberculosis (Mtb) that primarily affects the lungs. In Phase I research, nanoRETE demonstrated proof-of-concept of an electrochemical nano-bead biosensor for measuring plasma cytokine and chemokine concentrati ...

We propose to carry out a three-phase R & D project leading to a scalable, easy-to-use Cohort Builder software tool making it possible for clinical practitioners and quality assurance personnel to carry out comparative health research studies quickly and effectively, without the need for in-depth data or analytics expertise. In Phase I, we will investigate strategic, operational, and technical iss ...