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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. UHMWPE Composite Material for Joint Implants

    SBC: TDA Research, Inc.            Topic: NIAMS

    DESCRIPTIONprovided by applicantIn this SBIR Phase II projectthe mechanical and fatigue related properties of ultrahigh molecular weight polyethyleneUHMWPEjoint implant materials will be improved by creating a composite material with carbon reinforcementsUHMWPE has long been widely used as wear surfaces in joint implantsand further improvements to its wear resistance have been obtained by cross li ...

    SBIR Phase II 2015 Department of Health and Human Services
  2. Selenium-derivatized New Reagents for Nucleic Acid X-ray Crystallography

    SBC: SENA RESEARCH, INC.            Topic: NIEHS

    DESCRIPTION provided by applicant There are growing demands for D structure determination of nucleic acids and their protein complexes for understanding disease molecule level mechanisms and discovering innovative drugs X ray crystallography is one of the most direct and powerful tools for structure determination of these macromolecules and complexes However the crystallization and phase d ...

    STTR Phase II 2015 Department of Health and Human Services
  3. Thermal Ground Planes for High Power Solid-State Lasers

    SBC: i2C Solutions, LLC            Topic: MDA13022

    A key challenge toward future directed energy systems is the development of power and thermal management technologies needed to support the laser systems, particularly pump diodes.I2C Solutions and the University of Colorado have developed a Thermal Ground Plane (TGP) technology that interfaces with doide laser bars in order to spread heat and transport it to the laser cooling loop.During Phase II ...

    SBIR Phase II 2015 Department of DefenseMissile Defense Agency
  4. Digital Star HIV Prevention for Youth in Mental Health Treatment

    SBC: VIRTUALLY BETTER INC            Topic: 105

    DESCRIPTION provided by applicant Adolescents in mental health treatment are at greater risk for HIV and other STIs than their peers due to an earlier age of onset of sex less protected sex more sexual partners and more frequent substance use This greater risk is due to multiple factors including cognitive misperceptions affect dysregulation and less self efficacy The numerous adolescent ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Flexible CPU-GPU computational plasma applications with particles and fluids

    SBC: TECH-X CORPORATION            Topic: SB143002

    Theoretical computing speeds have increased dramatically in the last decade with chip advances, including Graphics Processor Units (GPUs).In practice, however, these gains have not been realized, largely due to the accompanying high development costs due to the need for multiple code bases to take advantage of the various chips and their variants.The proposed project addresses these issues from bo ...

    SBIR Phase II 2015 Department of DefenseDefense Advanced Research Projects Agency
  6. BMX-001 as a Therapeutic Agent for Treatment of High-Grade Gliomas

    SBC: BIOMIMETIX JV LLC            Topic: NCI

    DESCRIPTION provided by applicant Phase and Phase clinical trials of a new class of redox active pharmaceutical are proposed in high grade glioma WHO grade III and IV This project will test a compound that crosses the blood brain barrier and which prevents hippocampal stem cell loss and white matter degradation following radiation therapy RT The compound also inhibits tumor regrowth f ...

    SBIR Phase II 2015 Department of Health and Human Services
  7. Thermal Isolation Technology for Large-Format Li-ion Batteries

    SBC: ADA Technologies, Inc.            Topic: AF141071

    ABSTRACT:Large format lithium-ion batteries with ineffective cell isolation are potentially hazardous when exposed to conditions such as crush, overcharge, discharge, high temperature and internal short circuit. The recent Boeing incidents and similar incidents in the automotive industry underscore the importance of current research into the root causes and safety hazards associated with such batt ...

    SBIR Phase II 2015 Department of DefenseAir Force
  8. High Performance Microminiature Free Space Shutter for CAMS

    SBC: Coldquanta, Inc.            Topic: SB142005

    ColdQuanta proposes the development, fabrication, testing and demonstration of a free-space microshutter based on MEMS technology. The microshutter head will provide extinction ratios exceeding 70 dB and shutter transition times below 10 us, and it will be smaller than any other free space shutter technology currently available. The proposed shutter leverages prior experience with the successful d ...

    SBIR Phase II 2015 Department of DefenseDefense Advanced Research Projects Agency
  9. Single Somatic Cell Epigenetic Models

    SBC: Topogen, Inc            Topic: 200

    DESCRIPTION provided by applicant Epigenetic modifications of DNA and histones are stable encryption systems essential for life For example the importance of DNA methylation is underscored by the consequences of its mis regulation which include defects in tissue homeostasis chronic disease and accelerated aging thus epigenetics broadly impacts human health The information stored in the di ...

    SBIR Phase I 2015 Department of Health and Human Services
  10. Portable Microwave Cold Atomic Clock

    SBC: Spectra Dynamics Inc            Topic: SB141004

    We present the design of a small, portable, microwave cold atomic clock that meets the frequency stability requirement of

    SBIR Phase II 2015 Department of DefenseDefense Advanced Research Projects Agency

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