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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Gradient Interphase, 3-D Fiber Architecture CMC's

    SBC: 3TEX, Inc.            Topic: N/A

    A clear need exists for the next generation of Ceramic Matrix Composites (CMC) for Thermal Protection Systems (TPS), propulsion hardware, and other high temperature applications. No "off-the-shelf" materials and/or processes capable of meeting NASA's goals are available, yet completely integrating a unique combination of commercially available or nearly commercially available technologies can m ...

    STTR Phase I 2006 National Aeronautics and Space Administration
  2. Auto-antibody profiling of non-small cell lung cancer

    SBC: 20 20 Genesystems Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Tumor markers, measured in peripheral blood, could assist in diagnosis and management of non-small cell lung cancer (NSCLC) and potentially improve historically dismal outcomes. Circulating antibodies, generated to a wide range of tumor-associated proteins, can be translated into a valuable blood test for lung cancer. Preliminary data supports this hypothesis. ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Oral Formulation of Zonulin Antagonist AT-1001 for Diabe

    SBC: ALBA THERAPEUTICS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The trigger for autoimmune destruction of pancreatic beta cells in Type 1 diabetes (T1D) is unclear. Evidence exists for the role of increased intestinal permeability, secondary to intestinal tight junctions (tj) disassembly, in the pathogenesis of various autoimmune diseases including T1 D. Over the last decade our studies have focused on the mechanism(s) of a ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Expired CO2/O2 Analysis to Diagnose Pulmonary Embolism

    SBC: BREATHQUANT MEDICAL SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A rapid, noninvasive, and accurate, point-of-care device to diagnose and exclude pulmonary embolism (PE) remains an unmet need, especially for patients with conditions that activate inflammatory and coagulation pathways and therefore predispose to PE. These conditions include surgery, cancer, age >70 years, prolonged hospitalization, hemodialysis, connective ti ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Validation and Quantification of FFPE Antigen Retrieval by Proteome Analysis

    SBC: CALIBRANT BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Because of the long history of the use of formalin as the standard fixative for tissue processing in histopathology, there are a large number of archival formalin-fixed and paraffin-embedded (FFPE) tissue banks worldwide. These FFPE tissue collections, with the attached clinical and outcome information, present invaluable resources for conducting retrospective ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Expanding Computer-Based Drug Abuse Prevention

    SBC: HEALTHSIM, INC.            Topic: N/A

    Recent evidence indicates that the prevalence of substance abuse is significant among children and adolescents, and initiation of drug use is often occurring at very early ages. These findings underscore the need to initiate age-appropriate prevention efforts with youth at an early age in elementary school and continue these interventions throughout middle school and later years. We previously ...

    STTR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  7. Recovery /preservation of donation cardiac death livers

    SBC: HEPATOSYS INC            Topic: N/A

    Recovery /preservation of donation cardiac death livers

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Med-eMonitor: A Web-Enabled HIV ART Adherence Monitoring Device and System

    SBC: INFORMEDIX HOLDINGS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Adherence to HIV antiretroviral therapy (ART) is closely associated with viral suppression, drug resistance and disease progression. Although near perfect adherence is needed for reliable viral suppression, average adherence to HIV antiretroviral therapy is under 70%. Accurate assessment of adherence is the first step in improving adherence because it identifie ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Suicide of HIV-Infected Cells by TAT-Inducible shRNA

    SBC: LENTIGEN CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of the proposed project is to generate the pre-clinical data necessary to provide proof-of-principle for future clinical studies of pro-apoptotic lentiviral vector (LV) gene therapy using small hairpin RNA (shRNA) to target ?HIV-Associated Life Preserver? (HALP) and ring finger protein 7 (RNF7), two of the crucial anti- apoptotic genes in acquired HIV ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  10. Tools for High Throughput Protein Crystallization and Structure Determination

    SBC: MITEGEN, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Project Summary: The NIH has committed substantial resources to both traditional and - through its Protein Structure Initiative - high-throughput approaches to protein structure determination, and similar commitments have been made in Europe and Asia. A survey of the results for soluble proteins shows that the main bottlenecks are obtaining high-quality crystal ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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