Award Data

DESCRIPTION (provided by applicant): Delays in FDA drug approval are measured in lost lives (estimated to be hundreds of thousands over the last few decades) and increased costs to U.S. citizens for drugs that are eventually approved. One factor contributing to the delay in drug approvals is the widespread use of time-consuming and error-prone manual methods to deliver medical images (i.e. CT, MR, ...

DESCRIPTION (provided by applicant): The morbidity and mortality due to cardiovascular disease is attributed to the lack of significant replicative potential of adult mammalian cardiomyocytes. Thus myocyte loss in response to ischemic injury typically results in scar formation and a decline of cardiac function that is usually irreversible. The cessation of myocyte proliferation is associated with ...

Phase I demonstrated the technical feasibility of creating surface acoustic wave (SAW) based humidity sensors that respond rapidly (under 0.5 second) and reversibly to a wide range of humidity levels using nanoparticle and thin polymer films. This proposal describes a Phase II effort that will result in the development of multiple uniquely identifiable, wirelessly interrogable, passive humidity s ...

DESCRIPTION (provided by applicant): TOPIC - Tooth Phone(R) Auditory Device - TPAD ABSTRACT The Tooth Phone(R) Auditory Device - TPAD is new alternative device to the only direct bone conduction hearing aid currently accepted by the Food and Drug Administration (FDA) for the treatment of certain specific types of hearing loss. Unlike the precedent FDA approved device that uses an osseointegrated i ...

This project will demonstrate the benefits of a partial emission pump coupled with a zero net positive suction pressure inducer design to achieve robust, deep throttling capability. This pump application is well suited for 5k to 15k lbf thrust range rocket engines.

DESCRIPTION (provided by applicant): Some 1.8 million regenerative dental procedures were done in the U.S. in 2006. Of these, about 20% used a wound-healant product such as a recombinant growth factor (RGF) or concentrates of a patient's own platelets [requiring the use of a platelet concentrating system (PCS)]. Wound-healants are used as an attempt to accelerate healing and to improve patient ou ...

DESCRIPTION (provided by applicant): Degenerative joint diseases such as osteoarthritis remain the source of significant pain and disability, affecting 20 million adults with an economic burden of over 40 billion per year to the United States. While joint replacement is a well-established procedure, its finite life span makes this treatment unacceptable for younger or more active individuals, of ...

DESCRIPTION (provided by applicant): Analysis of DNA is important in many applications including forensics, diagnostic genetic testing and biomedical research. Genomic DNA analysis uses chemical amplification methods such as polymerase chain reaction (PCR) amplification of a target sequence to increase the amount of the genetic fragment under study. This is essential for sequencing which promises ...

DESCRIPTION (provided by applicant): We have defined a Phase I program for establishing a system that will destroy pharmaceuticals in drinking water by leveraging Eltron's PeroxEgen and proprietary photocatalysts which will be developed in Phase I research. PeroxEgen is an H2O2 and peracetic acid (PAA) generating device that is nearing commercial readiness. Wastewater, doped with PeroxEgen -gene ...

Over the next decade, a host of new technologies and capabilities will be needed by NASA to support Project Constellation. For risk reduction considerations, it is desirable that they be flown on other missions prior to use on vehicles such as Orion or Altair. An innovative and cost-effective approach to doing so is to use picosats, which are miniaturized spacecraft with masses on the order of a ...