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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Automating and Obtaining FDA Approval for a Digital Intervention for Depression

    SBC: HEALTH RHYTHMS INC            Topic: 104

    Phase IIB Abstract -FINAL A large body of evidence supports the idea that disruptions in the regularity of behavioral routines (or ‘social rhythms’) can lead to the onset of mood symptoms and full-blown episodes via their impact on endogenous circadian rhythms and, conversely, that stable social routines protect against new mood episodes. Based on our conviction that monitoring, evaluating, an ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  2. DT-EGF Toxic Fusion Protein for the Treatment of Bladder Cancer

    SBC: Aurora Oncology, Inc.            Topic: 399

    Project Summary/Abstract Bladder cancer causes over 165,000 annual deaths worldwide with 70,000 new cases and 16,000 deaths reported in the US. Treatment of superficial bladder cancer by resection and BCG administration is unsuccessful in 40% of cases with recurrences eventually requiring cystectomy or other aggressive therapy; new therapies are needed. The role of Epidermal Growth Factor Receptor ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  3. Cartilage Regeneration with Tunable Inflammation Resistance

    SBC: Cytex Therapeutics, Inc.            Topic: R

    Abstract: Femoroacetabular impingement or FAI is a commonly diagnosed condition affecting a younger patient population than the general osteoarthritis (OA) population. Untreated, FAI invariably leads to OA and, ultimately, total hip arthroplasty (THA). The fact that most FAI diagnoses are made in patients under the age of 40, with many in their late teens and twenties, makes FAI all the more clini ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a nitric oxide-releasing antiviral gel for the treatment of cervical HPV infections and prevention of downstream malignancies in women

    SBC: Novan, Inc.            Topic: R

    HPV is the United States’ most prevalent sexually transmitted infection and thehigh-risk subtypes are of significant public health interest given that high-risk HPV (HR-HPV) infections have beenconclusively linked to the development of certain cancers. Cervical intraepithelial neoplasias(CIN), caused by persistent HR-HPV infection, are categorized by grade, with high grades 2and 3 being consider ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  5. A Novel Immunological Probiotic for Treating Inflammatory Bowel Disease

    SBC: Rise Therapeutics, LLC            Topic: 300

    Project Summary The goal of this project is to develop a novel immunologically designed probiotic therapy to inhibit gut inflammatory processes for the treatment of inflammatory bowel disease (IBD). Over 3 million adults in the U.S. suffer from IBD, an umbrella term encompassing two chronic inflammatory diseases of the gastrointestinal tract: Crohn’s disease (CD) and ulcerative colitis (UC)6. IB ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  6. An Integrated Software Platform for Accelerating Image-Driven Ophthalmic Research and Driving New Insights and Endpoints to the Clinic

    SBC: Translational Imaging Innovations, Inc.            Topic: NEI

    Project Summary Translational Imaging Innovations (TII) is creating an integrated platform for the collection, curation, analysis and sharing of ocular images and data. Our Integrated Translational Imaging™ platform integrates an electronic research workflow management system with an image repository, or data lake, and provides methods for controlling the flow of images and data to a visualizati ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  7. Effect of Validated Skills Simulation with the Miya Model on Operating Room Performance of Vaginal Hysterectomy

    SBC: MIYAZAKI ENTERPRISES LLC            Topic: NICHD

    Miya Model™ Simulator: Phase II B Abstract OB/GYN Residents must develop numerous skills including pelvic exams, childbirth, open surgery, laparoscopic surgery, and vaginal surgery. Studies demonstrate that OB/GYN Residents lack training in vaginal surgical techniques, including Vaginal Hysterectomy (VH), the desired hysterectomy technique recommended by The American College of Obstetricians and ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Business Encounters: Life Scientist Simulation Experience to Enhance Entrepreneurial Intent and Self-efficacy

    SBC: Clinical Tools, Inc            Topic: 500

    Business Encounters: Life Scientist Simulation Experienceto Enhance Entrepreneurial Intent and Self-efficacy In FY 2019, the NIH invested $26 billion in 49,000 research project grants. Commercialization of that work is essential to the nations health and driven by a vibrant community of biomedical startups, incubators and funding options. Life scientists are key to those startups yet women life sc ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  9. Pudendal neuromodulation for urinary and fecal incontinence and sphincter dyssynergia

    SBC: Dignify Therapeutics LLC            Topic: NINDS

    SUMMARY / ABSTRACTSpinal cord injury (SCI) frequently produces severe, life-long bladder and bowel dysfunction that results in urinary (UI) and fecal incontinence (FI), as well as sphincter dyssynergia that results in urinary retention and fecal impaction. Current standard of care for incontinence consists of modestly effective drugs, complicated surgery, or adult diapers. Bladder and bowel voidin ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  10. A Novel Polymeric Valve for Transcatheter Aortic Valve Replacement

    SBC: POLYNOVA CARDIOVASCULAR INC            Topic: NHLBI

    Project Summary: A Novel Polymeric Valve for Transcatheter Aortic Valve Replacement Minimally invasive transcatheter aortic valve replacement (TAVR) has emerged as an effective therapy for the unmet clinical need of inoperable patients with severe aortic stenosis (AS). Recent longitudinal follow-up studies of TAVR patients however indicate that this procedure and associated technology may result i ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
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