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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Polymeric Valve for Transcatheter Aortic Valve Replacement

    SBC: POLYNOVA CARDIOVASCULAR INC            Topic: NHLBI

    Project Summary: A Novel Polymeric Valve for Transcatheter Aortic Valve Replacement Minimally invasive transcatheter aortic valve replacement (TAVR) has emerged as an effective therapy for the unmet clinical need of inoperable patients with severe aortic stenosis (AS). Recent longitudinal follow-up studies of TAVR patients however indicate that this procedure and associated technology may result i ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  2. Development of novel Amadorins for Diabetic Peripheral Neuropathy

    SBC: Praetego Inc            Topic: 200

    PROJECT SUMMARY Diabetic peripheral neuropathy (DPN) is the most common diabetic complication. DPN is a leading cause for disability due to foot ulceration and amputation, gait disturbance, and fall-related injury. There is no FDA- approved disease modifying treatment for DPN, a condition affecting up to 50% of the estimated 30 million diabetic patients in the US. Neuropathy occurs in patients wit ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  3. KAPS Biotech: A novel biomarker to improve prostate cancer diagnosis

    SBC: KAPS BIOTECHNOLOGY LLC            Topic: 102

    Abstract Prostate cancer (CaP) is the most common non-skin cancer in men and third most common cause of cancer deaths in men. Black men experience a higher burden of incidence and mortality from CaP compared to White men. The Prostate-Specific Antigen (PSA) test, a commonly used biomarker for early diagnosis and management of CaP, cannot alone accurately predict the presence of CaP, its aggressive ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  4. Development and testing of a behavioral activation mobile therapy for elevated depressivesymptoms

    SBC: MOUNTAINPASS TECHNOLOGY LLC            Topic: 104

    PROJECT SUMMARY/ABSTRACT Depression is the leading cause of disability worldwide, with more than 300 million people affected. Most adults with depressive symptoms make at least one annual visit to a primary care physician (PCP). As such, primary care offers a ripe opportunity to identify and treat adults with depressive symptomatology. Yet, depression has historically been undertreated in primary ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  5. Lead compound discovery from proprietary mycobacterial strains for treatment of PTSD

    SBC: MYCOBACTERIA THERAPEUTICS CORPORATION            Topic: NCCIH

    Project Summary Immunoregulation, i.e., balanced expression of regulatory and effector T cells, is thought to be compromised in modern high-income settings due in part to reduced contact with commensal and environmentally derived bacteria, also known as “old friends”. Failed immunoregulation is thought to be one factor contributing to recent increases in stress-related and chronic inflammatory ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  6. Enhanced Software Tools for Detecting Anatomical Differences in Image Data Sets

    SBC: KITWARE INC            Topic: 105

    Project Summary Morphometric analysis is a primary algorithmic tool to discover disease and drug related effects on brain anatomy. Neurological degeneration and disease manifest in subtle and varied changes in brain anatomy that can be non-local in nature and affect amounts of white and gray matter as well as relative positioning and shapes of local brain anatomy. State-of-the-art morphometry meth ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  7. Multi-Modality Image Data Fusion and Machine Learning Approaches for Personalized Diagnostics and Prognostics of MCI due to AD

    SBC: MS Technologies Corporation            Topic: R

    Alzheimer’s Disease (AD) is a devastating neurodegenerative disease. The greatest treatment potential lies in early stages before irreversible brain damage occurs. Early treatment requires early detection of the disease. Imaging holds great promise for capturing early signs of AD. This capability can be substantially strengthened by integrating neuroimages of different modalities that characteri ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Low-temperature Chemical Looping Reforming Catalystsfor Small-footprint GTL

    SBC: CATALYTIC AND REDOX SOLUTIONS LLC            Topic: 22a

    Over 468 billion cubic feet of natural gas was flared in the United State in 2018. This emitted nearly 25 million tons of CO2 while wasting an important domestic energy resource. This “stranded” natural gas, co-produced by shale oil wells, was flared because it is not cost-effective to transport due to low energy density. Although it would be highly desirable to convert this currently flared n ...

    STTR Phase II 2020 Department of Energy
  9. Interference Coatings for High Energy and Average Power Femtosecond-class Lasers in the 0.8-2um Wavelength Range

    SBC: XUV LASERS, INC.            Topic: 28e

    The problem/situation that is being addressed concerns the development of ultrafast coatings that will meet the specifications of the DoE solicitation: “broad-bandwidth, laser damage threshold of 0.5 J/cm2 (1 ps), engineered using a process that is scalable to large areas.” Development of interference coatings (ICs) with superior laser damage is strongly motivated by the needs to scale near in ...

    STTR Phase II 2020 Department of Energy
  10. Key Components for the Implementation of High Repetition Rate Petawatt-class Lasers

    SBC: XUV LASERS, INC.            Topic: 25c

    Ultra-high power, ultrashort pulse lasers systems are the central tool driving many of the recent advances in high energy density plasma science. They enable the generation of high energy density relativistic plasmas, bright x-ray and gamma–ray bursts, energetics particle beams and neutrons, and drive applications such as shadowgraphy of inertial confinement fusion targets and fast ignition. How ...

    STTR Phase II 2020 Department of Energy
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