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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Development and validation of therapy for mucopolysaccharidosis III

    SBC: Phoenix Nest Inc.            Topic: 103

    Project Summary Sanfilippo diseasemucopolysaccharidosis type IIIMPS IIIis a devastating neurodegenerative lysosomal storage disorder of childhood whose pathologic features are neurologicslowing of developmentsevere behavioral problemsprogressive cognitive declinedementiaand decline in motor skills leading to immobilityunresponsivenessand deathWe have focused on MPS IIID caused by a deficiency of a ...

    SBIR Phase II 2018 Department of Health and Human Services
  2. STTR Phase II: Self-Health Management Informatics Platform: Improving Patient Engagement in Care Delivery

    SBC: SIPPA Solutions LLC            Topic: SH

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project is a patient-centric engagement process that offers the best chance for enabling a scalable approach towards achieving the triple aim of improving care quality and outcomes, controlling health care costs and utilization, and increasing patient satisfaction. Currently the national healthcare c ...

    STTR Phase II 2018 National Science Foundation
  3. Mobile Augmented Screening Tool to Increase Adolescent HIV Testing and Linkage to Care

    SBC: Digital Health Empowerment, Inc            Topic: NICHD

    ABSTRACTAdolescents face increased HIV riskinfrequent testinginconsistent linkage to careand a lack of prevention related knowledgeWe propose to address this by completing and evaluating the Mobile Augmented ScreeningMAStool to increase youth HIV testing via a tablet based intervention in clinical settingsand then use text messages to facilitate linkage to care for those who test positiveand deliv ...

    STTR Phase II 2018 Department of Health and Human Services
  4. Advanced Dynamic Clamp for Neuroscience

    SBC: Cytocybernetics Inc            Topic: 101

    The goal of this proposal is to develop a commercialplug and playuser friendlypowerful and reliable dynamic clamp systemto enable all neuronal electrophysiologists to be able to perform sophisticated dynamic clamp experimentswithout any requirement for programmingengineeringor mathematical modeling skillsWe will develop hardware and software specifically for neuroscience applicationsfocusing on th ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Enhanced Software Tools for Detecting Anatomical Differences in Image Data Sets

    SBC: Kitware, Inc.            Topic: 105

    Project SummaryMorphometric analysis is a primary algorithmic tool to discover disease and drug related effects on brain anatomyNeurological degeneration and disease manifest in subtle and varied changes in brain anatomy that can be non local in nature and effect amounts of white and gray matter as well as relative positioning and shapes of local brain anatomyState of the art morphometry methods f ...

    STTR Phase I 2018 Department of Health and Human Services
  6. Validation of a salivary miRNA diagnostic test for autism spectrum disorder

    SBC: Quadrant Biosciences Inc.            Topic: 103

    Autism spectrum disorderASDis a continuum of neurodevelopmental characteristics that includes deficits in communication and social interactionas well as restrictiverepetitive interests and behaviorsASD is an increasing public health concernwith aboutinAmerican children diagnosed with ASD inafold increase in prevalence over the pastyearsThe effect of ASD on both society and the economy is a large b ...

    STTR Phase II 2018 Department of Health and Human Services
  7. Evaluation of a Novel Infection PET Diagnostic

    SBC: CHRONUS PHARMACEUTICALS, INC.            Topic: NIBIB

    Project Summary Abstract Bacterial infections such as those of prosthetic jointsbonesosteomyelitisand heart valvesinfective endocarditisare difficult to difficult to diagnose and treatand are a major cause of mortalitymorbidity and health care costsThe long term goal of our program is thus to develop positron emission tomographyPETradiotracers that can be used for non invasive PET imaging to detec ...

    STTR Phase I 2018 Department of Health and Human Services
  8. STTR Phase II: HI-LIGHT- Solar Thermal Chemical Reactor Technology for Converting CO2 to Hydrocarbons

    SBC: Dimensional Energy Inc.            Topic: CT

    The broader impact/commercial potential of this STTR Phase II project will result in significant economic activity through the utilization of waste carbon dioxide. The photo-catalytic reactors funded in the project will lead to novel methods to chemically store energy from the sun. Each year, human activity releases 38 billion tons of carbon dioxide into the atmosphere. Dimensional Energy envision ...

    STTR Phase II 2018 National Science Foundation
  9. Novel Algae Technology for CO2 Utilization

    SBC: Helios-NRG, LLC            Topic: 18c

    There is an urgent need to significantly reduce CO2 emissions from coal burning power plants. Current CO2 capture technologies are too expensive and not economically viable. A new technology that can capture ~90% of the CO2 and significantly reduce the cost of capture is required for commercial viability. Statement of How this Problem is Being Addressed:This project is aimed at the development of ...

    SBIR Phase II 2018 Department of Energy
  10. HPC Obfuscation and Security Toolkit (HOST)

    SBC: ATC-NY, Inc.            Topic: 03a

    Large-scale computing systems, formerly relegated to research institutions and behind closed doors, are now often used for critical infrastructure modeling and control. These high-performance computing systems are frequently geographically distributed and exposed to the Internet, making them attractive resources for misuse and cyberattack. As high-performance computing systems grow even more popul ...

    SBIR Phase II 2018 Department of Energy

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