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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. CC49/RIGS, a diagnostic radiopharmaceutical monoclonal antibody, for enhanced liv

    SBC: Navidea Biopharmaceuticals, Inc.            Topic: 102

    DESCRIPTION provided by applicant After an interim period of inactivity based on a select alternative commercial focus and after consultation with the FDA Neoprobe Corporation is rapidly reinitiating efforts to develop and commercialize Iodine labeled HuCC CH anti Tumor Associated Glycoprotein TAG monoclonal antibody construct as an aid to cancer surgeons who are operating on pa ...

    SBIR Phase II 2015 Department of Health and Human Services
  2. Micro Patterned Intraocular Lens Membrane for Reducing Incidence of PCO

    SBC: Sharklet Technologies Inc.            Topic: N

    DESCRIPTION provided by applicant The exponential increase of diabetics and the elderly in the U S has more than tripled the number of cataract surgeries performed in just two decades As many as half of these surgeries will lead to posterior capsular opacification PCO which requires follow up Nd YAG laser capsulotomy surgery Without this additional procedure patients can suffer permanent ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Single Somatic Cell Epigenetic Models

    SBC: Topogen, Inc            Topic: 200

    DESCRIPTION provided by applicant Epigenetic modifications of DNA and histones are stable encryption systems essential for life For example the importance of DNA methylation is underscored by the consequences of its mis regulation which include defects in tissue homeostasis chronic disease and accelerated aging thus epigenetics broadly impacts human health The information stored in the di ...

    SBIR Phase I 2015 Department of Health and Human Services
  4. Location-based Smartphone Technology to Guide College Students??? Healthy Choices Phase II

    SBC: KLEIN BUENDEL, INC            Topic: NCCDPHP

    DESCRIPTION provided by applicant Poor eating habits sedentary behavior and deficient sleep quality are problematic for many college students Surrounded by numerous unhealthy food choices and physical activity barriers students are vulnerable to overweight and chronic diseases such as diabetes heart disease and cancer Todayandapos s college students are more technologically connected tha ...

    SBIR Phase II 2015 Department of Health and Human Services
  5. Optimization and Lead Selection of Novel Antimycobacterial Agents

    SBC: CRESTONE, INC.            Topic: 300

    DESCRIPTION provided by applicant The nontuberculous Mycobacteria NTM are a growing public health concern as the number of opportunistic infections increases Although not a reportable disease there is growing epidemiologic evidence to suggest that NTM cause more infections today in the United States than Mycobacterium tuberculosis Mtb yet unlike Mtb there are few dedicated antimicrobial ...

    SBIR Phase II 2015 Department of Health and Human Services
  6. Intraoperative assessment of non-melanoma skin cancer margins using NIRF probes.

    SBC: Akrotome Imaging, INC            Topic: 102

    DESCRIPTION provided by applicant It is predicted that approximately people will be diagnosed with nonmelanoma skin cancer this year in the United States Seventy five percent of these patients will undergo traditional excisional surgery i e non Mohs Micrographic Surgery non MMS Unlike MMS surgery traditional excision surgeries do not employ methods to determine the status of the ...

    SBIR Phase II 2015 Department of Health and Human Services
  7. BMX-001 as a Therapeutic Agent for Treatment of High-Grade Gliomas

    SBC: BIOMIMETIX JV LLC            Topic: NCI

    DESCRIPTION provided by applicant Phase and Phase clinical trials of a new class of redox active pharmaceutical are proposed in high grade glioma WHO grade III and IV This project will test a compound that crosses the blood brain barrier and which prevents hippocampal stem cell loss and white matter degradation following radiation therapy RT The compound also inhibits tumor regrowth f ...

    SBIR Phase II 2015 Department of Health and Human Services
  8. Personal Exposure Monitoring of the Air Pollutants as a K-12 Educational Tool

    SBC: 2B TECHNOLOGIES, INC.            Topic: NIEHS

    DESCRIPTION provided by applicant Personal Exposure Monitoring of Air Pollutants as an Educational Tool in the GO Treks project launched by the Phase I grant students at schools throughout the U S used personal monitors to measure the air pollutants black carbon and ozone along treks of their own design The treks were uploaded to blogs in the GO website where they were displ ...

    SBIR Phase II 2015 Department of Health and Human Services
  9. Telemetric Microsensor for Glaucoma

    SBC: H-CUBED            Topic: NEI

    DESCRIPTION provided by applicant Glaucoma is an optic nerve disease in which there is progressive loss of retinal ganglion cells leading to irreversible loss of vision It is estimated o affect of the general population More than million Americans are affected with glaucoma and it is estimated to account for nearly $ B in direct medical costs It is estimated that of Caucasian patie ...

    SBIR Phase I 2015 Department of Health and Human Services
  10. Liquid Helium Bath Free, Conduction Cooled Nb3Sn Superconducting 7 Tesla Plus Mag

    SBC: HYPER TECH RESEARCH, INC.            Topic: 102

    DESCRIPTION provided by applicant For tesla full body MRI bore magnet systems NbTi superconductor wire has reached its limit at K Above T if NbTi is used it requires super cooling of helium to K to achieve T bore MRI and NMR systems All these T full body MRI background magnets sold by Siemens Philips and GE have been manufactured by Aligent formerly known at Varian befor ...

    SBIR Phase II 2015 Department of Health and Human Services

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