List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Feasibility study of a nanostructural system for bone regeneration in preparation for dental implants

    SBC: NuShores Biosciences LLC            Topic: 100

    Project SummaryCurrent bone grafting techniques for functional rehabilitation with dental implants have limitationshighcostdifficulties with fixation and stabilizationinsufficient bone regenerationhigh morbidity using autogenous block grafts and prolonged healing of up tomonthsExisting synthetic bone fillers cannot match defect shape and volumeare weakly resorbedif at allare not easily and quickly ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. Modified Partitioned Aquaculture System (P.A.S.) To Produce High Value Fish For Human Consumption

    SBC: J M MALONE & SON INC            Topic: 87

    The traditional fish farming industry in the U.S. is currently faced with rising costs, labor shortages, competition from lower cost imports, increasing environmental regulation, and decreasing water supplies. Sales of the domestic channel catfish industry alone fell from $423 million in 2011 to $301 million in 2014. Catfish acreage in Arkansas which totaled 30400 acres in 2007 (NASS 2008), was re ...

    SBIR Phase II 2018 Department of Agriculture
  3. Novel therapeutic approach in treatment of glioblastoma using sustained delivery of Connxin43 carboxy-terminal peptide encapsulated in biodegradable nanoparticles in combination with temozolomide

    SBC: FirstString Research, Inc            Topic: 102

    PROJECT SUMMARY GlioblastomaGBMis an incurable cancer even with aggressive therapies such as surgical resection followed by radiotherapy and chemotherapy using temozolomideTMZEfforts to improve surgical resection or the efficacy of irradiation are limited by the potential damage these interventions cause to the brainIn contrastsensitizing GBM to TMZ is an appealing strategy because TMZ has excelle ...

    SBIR Phase II 2018 Department of Health and Human Services
  4. Development of a Low-Profile Dual Hormone Patch Pump with Novel Occlusion Sensor

    SBC: Sfc Fluidics, Inc.            Topic: 200

    Development of a Low Profile Dual Hormone Patch Pumpwith Novel Occlusion Sensor Project SummaryThe Specific Aim of this project is to develop a discretelow profiledual hormone drug delivery system using SFC Fluidicsenabling microfluidic technologiesA DualPumpwill be developed in which one proprietary ePumpbody will independently and accurately deliver both insulin and glucagon from two separate re ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. Rational Design of sub-100 nm Polystyrene Particles with a Low Coefficient of Variation in Size

    SBC: Tetramer Technologies,L.L.C.            Topic: NA

    During this Phase II SBIR development program, Tetramer Technologies will develop highlymonodisperse 100-nm and sub-100-nm diameter nanoparticles for use as latex size standards. Highlymonodisperse nanoparticle latexes are needed for improved calibration of electron microscopes, lightscatteringparticle sizing instruments, atomic force microscopes, and particle counters/contamination monitors used ...

    SBIR Phase II 2018 Department of CommerceNational Institute of Standards and Technology
  6. Rugged, Long-Life Flow Monitoring for Enhanced Geothermal Systems

    SBC: OZARK INTEGRATED CIRCUITS, INC.            Topic: 12a

    Access to the earth’s subsurface requires technologies that can operate at extremely high temperatures and pressures. Enhanced geothermal systems (EGS) require drilling deep and hot wells; while making better use of each well through techniques such as fracking and zonal isolation. Establishing a well requires monitoring electronics that can produce temperature, pressure and flow profiles in the ...

    SBIR Phase II 2018 Department of Energy
  7. Development of new anti-epilepsy treatments targeting cellular energetics through mitochondrial modulation with optimal pharmacokinetics and toxicity profiles

    SBC: Neuroene Therapeutics, LLC            Topic: 105

    Neuroene Therapeutics is a biotech company established to develop and commercialize safe effective therapies for epilepsyinpeople develop epilepsy in their lifetimehowever the currently available antiepileptic drugsAEDshave several issues and liabilities that leave unmet market needssuch asnot controlling seizures forof patients with epilepsycurrent AEDs only treat the symptoms of epilepsy and do ...

    SBIR Phase II 2018 Department of Health and Human Services
  8. Proteasome inhibitor re-sensitizing molecules for treatment of refractory multiple myeloma

    SBC: Leukogene Therapeutics Inc.            Topic: 102

    Project Summary Abstract Multiple MyelomaMMis the second most common form of blood cancer and remains an incurable and deadly diseaseProteasome inhibitorPItherapy is a cornerstone in the treatment of MMbut resistance to this class of agent is an emerging challenge in the clinicNew therapeutic approaches that specifically target resistance are needed to maximize responses and ultimately produce cur ...

    STTR Phase II 2018 Department of Health and Human Services
  9. Development of an Autism Spectrum Disorder Screening Test based upon Metabolic Profiling of Fresh Blood Samples

    SBC: CIRCA BIOSCIENCE, LLC            Topic: 102

    Autism spectrum disorderASDis a neurodevelopmental disorder characterized by significant deficits in reciprocal social interactionsimpaired communication and restrictedrepetitive behaviorswith a prevalence ofinchildren in the USEarly intervention programs have been shown to be effective for improving IQlanguageand social skills for toddlers as young asmonths of ageDiagnosis of ASD is currently bas ...

    STTR Phase I 2018 Department of Health and Human Services
  10. Multicolor Photoacoustic Malaria Detector

    SBC: CytoAstra, LLC            Topic: NIAID

    Summary Malaria continues to be a global health prioritywith almost half of the world s populationbillionat risk and arounddeaths each yearOvertreatment is caused by lack of diagnosis and contributes to resistancea huge threat as illustrated by artemisinin resistance in Southeast AsiaLittle progress has been made in the novel methods to diagnose malarialet alone in reliably identifying asymptomati ...

    STTR Phase I 2018 Department of Health and Human Services

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government