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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. On Demand Energy Activated Liquid Decontaminants and Cleaning Solutions

    SBC: TDA Research, Inc.            Topic: A12AT005

    On-site activated decontaminants will revolutionize chemical and biological decon because the activated solution is produced on demand, without the limitations of traditional pre-made mixtures. TDAs system uses electrical activation to convert battery power into reactive chemicals that quickly destroy chemical and biological warfare agents. Prior to activation, the decontaminant mixture can be saf ...

    STTR Phase II 2018 Department of DefenseArmy
  2. Capacitive removal of PFOA and PFOS from Drinking Water

    SBC: MAINSTREAM ENGINEERING CORPORATION            Topic: 17NCER1A

    Polyfluoroalkyl and perfluoroalkyl compounds (PFCs) have been used commercially since the 1940’s due to their high level of chemical stability, almost frictionless surface or waterproofing characteristics. Elevated levels of PFCs have been linked to cancer and other health problems including reproductive and developmental risks. PFOA and PFOS are amongst the most prevalent of the PFCs with low l ...

    SBIR Phase I 2018 Environmental Protection Agency
  3. A Green Rooftop System for Commercial Buildings with Superior Energy Efficiency

    SBC: XIMAX Technologies Corporation Ltd            Topic: 17NCER6B

    This proposed project will develop a highly modularized green rooftop system that is not only longlasting but also assemble-able/disassemble-able. At roofs' end-of-life, it can be disassembled and_x000D_ 100% recycled. At buildings' end-of-life, if the roof still has enough useable life, it can be disassembled and reused elsewhere. Major environmental benefits of this technology are 1) nothing fro ...

    SBIR Phase I 2018 Environmental Protection Agency
  4. New Techniques for Real-Time Microsleep Assessment

    SBC: VERIFAX CORPORATION            Topic: NCCDPHP

    SUMMARY SignificanceImpaired alertness accompanied by short microsleep events is a frequently reported phenomenon in all areas of modem lifeA microsleep event can be defined as a somewhat unexpected short episode of sleepbetweenandsecondsthat occurs in the midst of ongoing wakeful activityPeople who experience microsleeps usually remain unaware of theminstead believing themselves to have been awak ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Peripheral FAAH inhibitor, URB937, as an opioid-sparing analgesic for chronic pain.

    SBC: AspireBio Corp            Topic: 101

    PROJECT SUMMARY Opioid drugs are powerful analgesicsbut their side effect profile strongly limits their useIndeedtheir addictive properties have led to an epidemic of abuse in the US that accounts forof the global utilization of prescription opioid analgesics in the USwith a market of over $billion per yearPrevious studies have shown that the endocannabinoid neurotransmitteranandamidecontrols noci ...

    STTR Phase I 2018 Department of Health and Human Services
  6. Emodin as a complementary dietary therapy to reduce toxicity of 5 fluorouracil

    SBC: AcePre, LLC            Topic: R

    PROJECT SUMMARYfluorouracilFUhas been the first choice chemotherapy drug for colorectal cancerCRCfor many yearshoweverits clinical utility remains hindered by hematopoietic and gastrointestinal toxicities resulting from its non selectivitySide effects include fatigueloss of appetiteand diarrhea among othersall of which can lead to reduced quality of lifeThe economic burden associated with chemothe ...

    STTR Phase I 2018 Department of Health and Human Services
  7. Mitigating Injurious Falls in Older Adults Through Non-Injurious Fall and Gait Analysis From Floor Vibrations

    SBC: ADVANCED SMART SYSTEMS AND EVALUATION TECHNOLOGIES, LLC            Topic: NIA

    Project Summary and Abstract Falls are the leading cause of death due to injuryThis simple motion is so common thatof community dwelling older adultsandof long term care facilities will experience a fall in the coming yearThe risk of falling substantially increases for those having Alzheimer s disease and related dementiasand those with Parkinson s diseaseThe financial burden is significant with f ...

    STTR Phase I 2018 Department of Health and Human Services
  8. Development of Spleen Tyrosine Kinase (SYK) negative allosteric modifiers for therapeutic intervention in Alzheimer's disease.

    SBC: ARCHER PHARMACEUTICALS, INC.            Topic: NIA

    Pathological hallmarks of Alzheimerandapos s diseaseADinclude extracellular deposits of Apeptidesintraneuronal aggregates of abnormally phosphorylated tau protein and neuroinflammationMost proposed AD disease modifying therapies have focused on strategies that reduce brain Aamyloid or tau pathological accumulationHoweversuch approaches have been unsuccessful in late stage AD clinical trials and ma ...

    STTR Phase I 2018 Department of Health and Human Services
  9. A Phase 2b Clinical Trial to Study the Efficacy of Longeveron Mesenchymal Stem Cells (LMSCs) to Treat Aging Frailty

    SBC: Longeveron LLC            Topic: NIA

    Aging Frailty is a biologically driven geriatric syndrome of multisystem physiological decline that is distinct from normal aging and disproportionately increases vulnerability to adverse clinical outcomesFrailty has an overall prevalence ofof thoseyears and olderand there is growing awareness in the geriatric community to diagnose and treat this conditionas it is not an inevitable consequence of ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. Reverse Engineering of MILSTAR Battery Pack

    SBC: MAINSTREAM ENGINEERING CORPORATION            Topic: DLA182003

    Increased competition and improved lead times are desired by the Defense Logistics Agency (DLA) for the MILSTAR system battery assembly. Mainstream Engineerings unique integration of engineering, manufacturing, quality control, and integrated logistics support (ILS) provides the government with the best value for the proposed NSN.The MILSTAR nickel-metal hydride battery pack lacks sufficient comme ...

    SBIR Phase I 2018 Department of DefenseDefense Logistics Agency

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