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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. High Fidelity Acoustic Scattering Models for Large Objects

    SBC: Applied Research In Acoustics LLC            Topic: N171080

    To address the Navy need for an accurate and efficient computational method for calculating acoustic scattering strength of midfrequency targets Applied Research in Acoustics LLC (ARiA) has built on recent advances in edge-source integral equation (ESIE) to develop and demonstrate the feasibility of a hybrid ESIE boundary-element method (BEM) target-scattering model for midfrequency active (MFA) s ...

    SBIR Phase II 2018 Department of DefenseNavy
  2. Proteasome inhibitor re-sensitizing molecules for treatment of refractory multiple myeloma

    SBC: LEUKOGENE THERAPEUTICS INC            Topic: 102

    Project Summary Abstract Multiple MyelomaMMis the second most common form of blood cancer and remains an incurable and deadly diseaseProteasome inhibitorPItherapy is a cornerstone in the treatment of MMbut resistance to this class of agent is an emerging challenge in the clinicNew therapeutic approaches that specifically target resistance are needed to maximize responses and ultimately produce cur ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Immersive Virtual Reality as a Tool to Improve Police Safety in Adolescents and Adults with ASD

    SBC: Floreo, Inc.            Topic: 103

    Floreo Technology proposes to develop the Police Safety Module (PSM), an innovative, immersive mobile virtual reality (VR) application designed to train police safety in adolescents and adults with autism spectrum disorder (ASD). ASD has been increasing in prevalence over recent years. While much attention has been paid to the causes and early diagnosis of ASD, there remains a clear need for effec ...

    STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Tools for Sharing and Analyzing Neuroscience Data

    SBC: FlashX, LLC            Topic: SB163001

    FlashX, LLC is developing the open source “Gigantum” software platform to ensure the accessibility, repeatability, and extensibility of scientific data and analyses. Our innovative software integrates into the tools that scientists already use, like Jupyter and RStudio, providing a transparent user experience with virtually no learning curve. Within these tools, Gigantum works behind the scene ...

    SBIR Phase II 2018 Department of DefenseDefense Advanced Research Projects Agency
  5. Novel therapeutic approach in treatment of glioblastoma using sustained delivery of Connxin43 carboxy-terminal peptide encapsulated in biodegradable nanoparticles in combination with temozolomide

    SBC: FirstString Research, Inc            Topic: 102

    PROJECT SUMMARY Glioblastoma (GBM) is an incurable cancer even with aggressive therapies such as surgical resection followed by radiotherapy and chemotherapy using temozolomide (TMZ). Efforts to improve surgical resection or the efficacy of irradiation are limited by the potential damage these interventions cause to the brain. In contrast, sensitizing GBM to TMZ is an appealing strategy because TM ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Administrative Supplement to Promote Diversity in Research and Development Small Businesses

    SBC: NEUROENE THERAPEUTICS INC            Topic: NINDS

    Abstract Neuroene Therapeutics is a biotech company established to develop and commercialize safe effective therapies for epilepsyinpeople develop epilepsy in their lifetimehowever the currently available anti epileptic drugsAEDshave several issues and liabilities that leave unmet market needssuch asnot controlling seizures forof patients with epilepsycurrent AEDs only treat the symptoms of epilep ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Simulation Education for Ebola Healthcare Team Competency

    SBC: SIMTUNES            Topic: NCEZID

    Project Summary This product will keep healthcare workers prepared and safe in the next lethal viral pandemic through innovative simulation education. Ebola and other deadly viral diseases represent a major threat to the nation and world. At its peak in December 2015 Ebola had infected 28,640 (including 4 in the U.S.) and killed 11,315 people (including 1 in the U.S.). By the end of 2014 tragicall ...

    SBIR Phase II 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  8. Development of an Autism Spectrum Disorder Screening Test based upon Metabolic Profiling of Fresh Blood Samples

    SBC: CIRCA BIOSCIENCE LLC            Topic: 102

    Autism spectrum disorderASDis a neurodevelopmental disorder characterized by significant deficits in reciprocal social interactionsimpaired communication and restrictedrepetitive behaviorswith a prevalence ofinchildren in the USEarly intervention programs have been shown to be effective for improving IQlanguageand social skills for toddlers as young asmonths of ageDiagnosis of ASD is currently bas ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Nucleobase aminosugars with reduced ototoxicity

    SBC: NUBAD LLC            Topic: Y

    PROJECT SUMMARYAminoglycosides are one of the cheapest and well known antibiotics in clinical use for overyearsbut one of the major limitations in their use is their ototoxicityWe are developing fast and low cost methods to develop aminoglycosides with antiribosomal activities and reduced toxicityIn this projectwe will identify novel aminoglycoside antibacterialsthat show reduced ototoxicityComple ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Medium Voltage Direct Current (MVDC) Casualty Power

    SBC: THE COLUMBIA GROUP INC            Topic: N162109

    In Phase II the TCG Team prototype MVDC casualty power system will be tested to validate its capability to restore MVDC power quickly and safely to electrical equipment in zones isolated from power generation by damage, through zones between the source and the rest of the system. During the Phase I Option, draft specifications were developed by the TCG Team based on the Phase I concept design. Pha ...

    SBIR Phase II 2018 Department of DefenseNavy
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