Award Data

Abstract Neuroene Therapeutics is a biotech company established to develop and commercialize safe effective therapies for epilepsyinpeople develop epilepsy in their lifetimehowever the currently available anti epileptic drugsAEDshave several issues and liabilities that leave unmet market needssuch asnot controlling seizures forof patients with epilepsycurrent AEDs only treat the symptoms of epilep ...

PROJECT SUMMARY ABSTRACT During Phase ISealCathLLC will test the feasibility of its innovative Double Balloon CatheterDBCwhich the United States Utility Patent application was approved on Augustand is in the process of issuing a patentLicensed from the Medical University of South Carolinathis DBC will be commercialized in Phase III as the trademarked nameCephus Catheterwith targeted end users bein ...

A Reliable Switched Angle SpinningSASProbe with GradientsPFGfor Proteins in Solid State NMR AbstractSolid state NMRssNMRbiotechnology is emerging as an alternative method of choice for highresolution structure determination for integral membrane proteinsIMPsssNMR provides a unique platform to investigate protein dynamicsand functional studies of wide range of biomolecules in their supramolecular a ...

SICOR and the Pennsylvania State University propose to further the technology for an advanced, human interactive, automated material handling/logistics system (AutoLog) or large array robot. The system will robotically traverse large area work a Together with user-centered material handling software and controls, employing advanced virtual tools, the concept enables this large array robot to: ...

ABSTRACT BSTRACT In an effort to reduce the use of animals for toxicity testingcompanies have developed bioengineered in vitro skin models to replace the Draize skin irritation testThe development of tissue models has been further pushed by the European Union that prohibited the use of animals infor collecting toxicological data on cosmetic ingredientsSupply of bioengineered tissues is a significa ...

Current hydropower facilities employ a variety of electrical and mechanical equipment that necessitate the use of lubricants to ensure efficient operation of said equipment. The lubricants, either oils or greases, aid in reducing friction, dissipating heat, prevent oxidation, and seal of water and debris from vital areas of the equipment. During operation, equipment may be submerged or otherwise c ...

Current agriculture and off-road equipment requires the use of lubricants to ensure efficient operation of integral hydraulic and gear driven systems. The lubricants, either oils or greases, aid in reducing friction, dissipating heat, prevent oxidation, and seal of water and debris from vital areas of the equipment. During operation, equipment may have slight leaks or suffer catastrophic failures ...

Two major areas of biomaterials which present the biomedical industry and orthopedic community with a formidable challenge pertain to their use in joint replacement and tissue engineering. Inability of most materials used in orthopedic implants to form an interfacial bond with bone is often associated with loosening and failure. This, and the growing interest in tissue engineering and the great ...

ABSTRACTWe propose combination of the rabbit cornea endothelial and epithelial cells with bioengineered scaffolds in cell culture well insertsThis technology could significantly reduce the use of rabbits for the Draize rabbit eye irritation assayThe barrier to commercialization is the lack of an effective method for storingbankingof living bioengineered cornea equivalentsWe will combine cell expan ...

CSMP is an exciting K-6 math program, designated as an "exemplary educational program that works¿ by the U.S. Department of Education, which funded its development, evaluation, and dissemination. Its spiral, problem solving approach uses picture languages, abaci, and technically challenging games. Simple problems subtly introduce sophisticated concepts. While class and teacher-student intera ...