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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Conundrum: A Project to Computerize the Comprehensive

    SBC: The Evans Associates            Topic: N/A

    CSMP is an exciting K-6 math program, designated as an "exemplary educational program that works¿ by the U.S. Department of Education, which funded its development, evaluation, and dissemination. Its spiral, problem solving approach uses picture languages, abaci, and technically challenging games. Simple problems subtly introduce sophisticated concepts. While class and teacher-student intera ...

    SBIR Phase I 1997 Department of Education
  2. Topic 346: Targeted Radionuclide Therapy of Neuroendocrine Tumors Using 212Pb-octreotate Analogs

    SBC: RADIOMEDIX, INC.            Topic: NCI

    A peptide receptor radionuclide therapy (PRRT) using [177Lu]/[90Y]-labeled somatostatin analogs has been proven to induce objective response in 30-45% of patients with advanced/progressive neuroendocrine tumors (NETs). The complete response to beta-emitter PRRT is rare. This is due to the fact that NETs are diagnosed at late stage of disease; the NETs patients with remissions could develop resista ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Topic 379: Extensible and Scalable Platform for Data Integration from Wearable Sensors to Generate Novel Analytics for Cancer Patients

    SBC: Litmus Health, Inc.            Topic: NCI

    The longterm objective of the Litmus Health platform is to allow researchers and clinicians to use data on cancer patients from wearables/sensors and smartphones. Collecting real-time, high-quality data from patients will transform care and clinical trials. Automating data collection, storage, analysis, and interpretation of data will result in better measurement of signs and symptoms and improved ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Topic 372: Highly multiplexed selection of aptamers to hundreds of canine immunotherapy targets

    SBC: Base Pair Biotechnologies, Inc.            Topic: NCI

    The preclinical development of cancer therapeutics, including the recent trend and focus on cancer immunotherapies, is evolving from the traditional use of mouse models to the use of other animal models including canine, rat, and minipig. Each of these non-mouse models carries its own advantages and abilities to increase the clinical relevance of the model as compared to mouse models. Yet, the wid ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Developing informatics tools to make immunology research data Findable, Accessible, Interoperable and Reusable

    SBC: Melax Technologies, Inc            Topic: NIAID

    Immunological research produces complex datasets ranging from molecular level to individuals and populationsSeveral data repositories aim to serve the community by housing and making the datasets available for reuseHowevertheir usage is still limited due to lack of standardizations and accessibilityOne common issue is that the datasets in these repositories are not available to generalized search ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Inhaled Delivery of Clofazimine- A High Efficiency, Flow Independent, Targeted, Low Cost DPI

    SBC: Via Therapeutics, LLC            Topic: NIAID

    Multidrug resistance tuberculosisMDR TBis a global healthcare concern compounded by poor compliance associated with lengthy drug susceptible TBDS TBtreatment regimensClofazimineCFZis highly active against MDR TBbut oral use is limited by systemic toxicityhyperpigmentationGI effectsand QT prolongationInhalation of CFZ will overcome these limitations by achieving high local concentrations of drug an ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health

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