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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Developing pan lyssavirus beta actin real time RT PCR assays for rabies diagnostics

    SBC: CyanVac LLC            Topic: ODCDC

    Rabies is a deadly zoonotic disease caused by rabies virusRABVand other lyssavirusesAnnuallyrabies causes approximatelyhuman deaths worldwideThe only widely accepted diagnostic test is the direct fluorescent antibodyDFAtestWhile rapid and sensitivethe DFA test requires expensivehighquality reagents and equipmentalong with trained diagnosticiansThese factors present economic and logistical barriers ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. Topic 376: Non-Invasive Subtyping of Aggressive Tumor and Its Environment- Moonshot

    SBC: INLIGHTA BIOSCIENCES L.L.C.            Topic: NCI

    Generation of high-resolution 3D anatomic and dynamic images without exposing patients to ionizing radiation renders MRI the preferred imaging modality for the detection of tumor extent and treatment response to neo-adjuvant and adjuvant medical therapies. The goal of this proposal is to develop a non-invasive, in vivo imaging-based platform that can repeatedly generate three-dimensional molecular ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Topic 373: Exonuclease Time-of-Flight for the Low-Cost, Rapid Identification of Methylated RNA Single Molecules

    SBC: Digital Nanogenetics LLC            Topic: NCI

    There is growing interest in the study of RNA modifications and its potential role(s) in many physiological abnormalities, such as modulating many processes associated with cancer development and progression. While RNA sequencing (RNA-seq) using short-read nextgeneration sequencing (NGS) have proven to be a useful tool for identifying specific RNA modifications, there still remains technical chall ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Media-based youth e-cig prevention toolkit for community-based organizations

    SBC: KDH Research And Communication, Inc.            Topic: NIDA

    KDH Research and CommunicationKDHRCsubmits this Fast Track SBIR proposal to develop and evaluate AVOIDAnti Vaping Online Information Disseminationa media based online toolkit to support community based organizationsCBOprevention programming against youth e cigarettee ciguseYouth e cig usealso known asvapingis a rapidly growing public health threatwith use among high school students tripling fromto ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. Effect of Repeated Administration of G-CSF on Hot Flashes and Other Vasomotor Symptoms of Menopause

    SBC: MENOGENIX, INC.            Topic: NIA

    One of the most common and distressing symptoms of menopause are hot flashesHot flashes and related symptoms represent a significant unmetworldwidehealthcare neednot only in women after surgical or natural menopausebut also in breast and prostate cancer patients undergoing hormone suppression or ablationHot flashes occur inof women undergoing natural menopause and approximatelymillion individuals ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Tools for drug efficacy studies in perfused tissue models

    SBC: Lena Biosciences, Inc.            Topic: 100

    Organ on a chip tools that recapitulate human biologyphysiology and pathology are urgently needed in applied science research and drug testing to expedite discoveries while reducing research costs and animal sacrificeUnfortunatelymost products incorporating circulation mimicking perfusion are too complicated for researchers to useincompatible with many protocols and readsand low throughputOur goal ...

    SBIR Phase II 2018 Department of Health and Human Services
  7. Online course to prepare promotores to support low-income Latino parents of children with special healthcare needs

    SBC: KDH Research And Communication, Inc.            Topic: NIMHD

    KDH Research andampCommunicationKDHRCsubmits this Fast Track SBIR proposal to developimplementand rigorously evaluate a culturally competentonline professional development course to prepare promotores to support low income Latino parents of children with special health care needsCSHCNas they navigate the education and health care systemsCSHCN experience poorer healthpsychosocialand academic outcom ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Device for Rapid, Complete & Durable Occlusion of Wide-Neck Cerebral Aneurysms

    SBC: Metactive Medical, Inc.            Topic: 106

    ABSTRACT Metactive Medical is developing the Ballstent Microcatheteran innovative medical device for the endovascular embolic treatment of cerebral aneurysmswhich are a common cause of strokeThe key component of the device is the Ballstentan expandabledetachablegold metal balloon that can be pleated and folded at the distal end of a delivery microcatheteradvanced into an aneurysm sac over a guidew ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. High-specificity affinity reagents for the detection of glycan sialylation

    SBC: GLYCOSENSORS AND DIAGNOSTICS, LLC            Topic: 300

    PROJECT SUMMARY Glycans have several distinct properties that make them potential disease biomarkersFirstlytheir location on cell surfaces makes them the first point of contact for cellular interactionsand thus they are crucial in the control of normal metabolic processesSecondlycell surface molecules are strategically exposed for surveillance by the immune systemwhere they may serve as immune rec ...

    SBIR Phase II 2018 Department of Health and Human Services
  10. New Techniques for Real-Time Microsleep Assessment

    SBC: VERIFAX CORPORATION            Topic: NCCDPHP

    SUMMARY SignificanceImpaired alertness accompanied by short microsleep events is a frequently reported phenomenon in all areas of modem lifeA microsleep event can be defined as a somewhat unexpected short episode of sleepbetweenandsecondsthat occurs in the midst of ongoing wakeful activityPeople who experience microsleeps usually remain unaware of theminstead believing themselves to have been awak ...

    SBIR Phase I 2018 Department of Health and Human Services

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