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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. DEVELOPMENT OF A LOW COST ETHYLENE OXIDE DETECTOR

    SBC: ADA Technologies, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  2. DEVELOPMENT OF A LOW-COST ETHYLENE OXIDE DETECTOR

    SBC: ADA Technologies, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  3. NON-ISOTOPIC MONOCLONAL IMMUNOASSAY FOR FENTANYL ANALOGS

    SBC: American Monitor Corp            Topic: N/A

    THE LONG TERM OBJECTIVE IS TO DEVELOP A HIGHLY AUTOMATED FLUORESCENCE POLARIZATION IMMUNOASSAY (FPIA) FOR FENTANYL AND ANALOGS. THE PHASE I SPECIFIC AIM IS TO SYNTHESIZE AND EVALUATE: 1) FLUORESCEIN LABELED FENTANYL ANALOGS USABLE IN A FPIA; 2) FENTANYL (HAPTEN) - PROTEIN CONJUGATES USED TO ELICIT AN IMMUNE RESPONSE IN BALB/C MICE; 3) MURINE MONOCLONAL ANTIBODIES TO FENTANYL AND ANALOGS. THE PHASE ...

    SBIR Phase I 1988 Department of Health and Human Services
  4. THE BIOLOGIC-PD; A NIGHTTIME PERITONEAL CYCLER

    SBC: ASH ACCESS TECHNOLOGY, INC.            Topic: N/A

    THE GOAL OF THIS PROJECT IS TO ADAPT AN EXISTENT SINGLE-ACCESS HEMODIALYSIS MACHINE, THE BIOLOGIC-HD(TM), TO PERFORM NIGHTTIME PERITONEAL DIALYSIS WITH HIGH DIALYSATE VOLUMES. A DISPOSABLE PACKAGE ON THIS MACHINE WILL INCLUDE A 30 LITER BAG WHICH INCLUDES DRY PREMEASURED AMOUNTS OF NAC1, NAHC03, GLUCOSE, AND CARBOXYLIC AMINO ACIDS. UNDER CONTROL OF THE BIOLOGIC MACHINE, 30 LITERS OF PURE AND STERI ...

    SBIR Phase I 1988 Department of Health and Human Services
  5. BIOLOGIC- DC SYSTEM FOR REMOVING CO2 FROM BLOOD

    SBC: ASH ACCESS TECHNOLOGY, INC.            Topic: N/A

    THE GOAL OF THIS PROJECT IS TO DEVELOP AN EXTRACORPOREAL DEVICE TO REVOVE LARGE AMOUNTS OF CARBON DIOXIDE (CO2) FROM A RELATIVELY SMALL FLOW RATE OF BLOOD. THIS DECARBOXYLATOR DEVICE COULD HELP SUPPORT PATIENTS WHEN RESPIRATOR FAIL TO REMOVE SUFFICIENT CO2 OR BE USED IN PLACEOF RESPIRATORS IN PATIENTS WITH MODERATE CO2 RETENTION. THE DECARBOXYLATOR SYSTEM WILL BE CREATED BY DEVELOPING A NEW DISPOS ...

    SBIR Phase I 1988 Department of Health and Human Services
  6. UREA MONITORING DURING DIALYSIS WITH THE BIOLOGIC-HD

    SBC: ASH ACCESS TECHNOLOGY, INC.            Topic: N/A

    WE HAVE DEVELOPED A DIALYSIS SYSTEM WHICH IS SIMPLE, SAFE, AND PORTABLE. THE BIOLOGIC-HD SYSTEM IS A SINGLE ACCESS, SORBENT BASED DIALYSIS SYSTEM WITH RECENTLY DEVELOPED MONITORS TO DETERMINE: TOTAL WEIGHT REMOVAL, BLOOD FLOW RATE, CLOTTING OF THE DIALYZER, AND COLUMN SATURATION (A CONTINUALLY OPERATING AMMONIUM MONITOR). THE AMMONIUM MONITOR CONTAINS A GAS-PERMEABLE MEMBRANE WHICH ALLOWS PASSAGE ...

    SBIR Phase I 1988 Department of Health and Human Services
  7. SUBCUTANEOUS INFUSION ACCESS DEVICE

    SBC: ASH ACCESS TECHNOLOGY, INC.            Topic: N/A

    CONTINUOUS SUBCUTANEOUS INSULIN INFUSION HAS BECOME AN IMPORTANT METHOD OF TREATING INSULIN DEPENDENT DIABETICS BECAUSE THE BETTER GLUCOSE CONTROL ACHIEVABLE BY THIS METHOD COULD POTENTIALLY REDUCE THE MORBIDITY AND MORTALITY ASSOCIATED WITH THE DISEASE. CURRENT SUBCUTANEOUS ACCESS IS VIA A NEEDLE TAPED IN PLACE. THE SUBCUTANEOUS INFUSION ACCESS DEVICE (SIAD) IS A SMALL IMPLANTABLE DEVICE WHICH CA ...

    SBIR Phase I 1988 Department of Health and Human Services
  8. ANTIBODIES TO HUMAN PANCREATIC TRYPSIN AND TRYPSINOGEN

    SBC: Athens Research And Technology            Topic: N/A

    THE DIAGNOSIS OF PANCREATITIS WOULD BE FACILITATED BY AN IMMUNOASSAY WITH INCREASED SPECIFICITY AND SENSITIVITY OVER THE EXISTING ASSAYS AVAILABLE TO THE CLINICIAN. THE INITIALOBJECTIVE OF THIS PROPOSAL IS TO DEVELOP SUCH AN ASSAY FOR ONE OF THE HUMAN PANCREATIC ENZYMES, CATIONIC TRYPSIN, WHICH IF PRESENT IN SERUM, IS INDICATIVE OF PANCREATITIS. SPECIFICALLY, WE WILL FOCUS ON THIS PROTEIN, ITS ZYM ...

    SBIR Phase I 1988 Department of Health and Human Services
  9. RAPID ASSAY FOR HUMAN A(1)-PROTEINASE INHIBITOR DEFICIENCY

    SBC: Athens Research And Technology            Topic: N/A

    N/A

    SBIR Phase I 1988 Department of Health and Human Services
  10. HOME SCREENING OF INFANT HEARING

    SBC: Bam World Markets Inc.            Topic: N/A

    A NEW, INNOVATIVE KIT FOR PARENT SCREENING OF INFANT HEARING(0-24 MONTHS) WILL BE DEVELOPED AND GIVEN TO 300 PARENT PAIRS TO VALIDATE A HOME SCREENING PROGRAM, USING SPECIAL FREQUENCY SOUND-MAKERS. OF THE APPROXIMATELY 4,000,000 BABIES BORN IN THE UNITED STATES EACH YEAR, OVER 1,000,000 DEVELOP HEARING PROBLEMS FROM RECURRENT OTITIS MEDIA DURING THEIR FIRST 24 MONTHS. APPROXIMATELY 8,000 OF THESE ...

    SBIR Phase II 1988 Department of Health and Human Services

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