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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Low X-Ray Dose Digital Mammography System

    SBC: BFE Acquisition Sub II, LLC            Topic: N/A

    The long term objective is to develop x-ray systems that will minimize x-ray radiation dose to the patient during clinical diagnosis and routine screening, while maximizing the usefulness of data by applying advanced sensing and signal processing techniques. Near theoretical limit x-ray sensitivity can be achieved with advanced semiconductor detector arrays, so x-ray radiation dose can be reduced ...

    SBIR Phase II 1995 Department of Health and Human Services
  2. P.A.S., Inc.- A private Personal Assistance Provider Model

    SBC: Meeting the Challenge, Inc.            Topic: N/A

    With nearly 10 million people as potential consumers of Personal Assistance Service (PAS), identifying effective methodologies for providing these services is vitally important. The growth of independent living has raised the level of visibility of consumer empowerment. At this time, very little solid data exist to indicate the level of PAS required or the preferred delivery model for the servic ...

    SBIR Phase II 1995 Department of Health and Human Services
  3. In Vitro Screen for Fungal Glucan Synthase Inhibitors

    SBC: MycoTox, Inc.            Topic: N/A

    Fungi are medically and economically very important, contributing to waste, spoilage and disease. Treatment of human fungal disease, especially in immunodeficient patients suffering from Acquired Immunodeficien- cy Syndrome, is hampered by the virtual lack of clinically useful drugs. Filamentous fungal morphogenesis and growth are the direct result of polysaccharide polymers and other materials be ...

    SBIR Phase II 1995 Department of Health and Human Services
  4. CELL CULTURE PRODUCTION OF TOXOPLASMA GONDII TISSUE CYST

    SBC: Paravax Inc.            Topic: N/A

    TOXOPLASMA GONDII STRAIN T-263 IS AN OOCYST NEGATIV GENETIC MUTANT THAT INDUCES IMMUNITY IN CATS TO WILD STRAINS WHEN TISSUE CYSTS OR BRADYZOITES ARE ADMINISTERED ORALLY. THE VACCINE POTENTIAL OF T-263 HAS BEEN PROVEN IN TWO SEPARATE EFFICACY STUDIES. USE OF THIS FELINE VACCINE WILL REDUCE OOCYST CONTAMINATION OF HOMES AND SURROUNDINGS THEREBY REDUCING ZOONOTIC TOXOPLASMOSIS IN HUMANS. PRODUCTION ...

    SBIR Phase II 1995 Department of Health and Human Services
  5. Oxylase--Low Cost, on Airway, Fast Oxygen Sensor

    SBC: Photonics Research, Inc.            Topic: N/A

    We will develop ultra-compact arrays of multi-wavelength diode lasers that have excellent beam quality for use in ophthalmology and other medical imaging applications. The arrays are based on vertical-cavity surface-emitting lasers (VCSEL). Unlike conventional diode lasers, VCSELs emit low-divergence, circularly-symmetric beams which are free from astigmatism and ideally suited for imaging applica ...

    SBIR Phase II 1995 Department of Health and Human Services
  6. Enhanced Fluorescence for Detection of Tumor Tissue

    SBC: PHYSICAL OPTICS CORPORATION            Topic: N/A

    The detection of several types of cancerous cells requires the use of spectroscopic fluorescence methods. The aim is to evaluate and implement a unique new method for improving the monitoring an analysis of tumor tissues through an approach based on the enhanced detection of weak optical signals. We will develop special holographic noise suppressing coatings, which are analogous to moth-eye struct ...

    SBIR Phase II 1995 Department of Health and Human Services
  7. Stereotactic Neurosurgical Ultrasound System

    SBC: Surgical Navigation Tech., Inc            Topic: N/A

    We are developing an image guided neurosurgery workstation called the NeuroStation (TM) withthe principle objective of providing intra-operative localization information to the neurosurgeon usingdiagnostic MRI and CT images. A natural and arguably necessary extension to image-guidedneurosurgery workstations is the ability to integrate real-time ultrasound imagery into the intra-operativelocalizati ...

    SBIR Phase II 1995 Department of Health and Human Services
  8. Advanced Zeoponic Plant Growth Media, Application Systems

    SBC: Boulder Innovative            Topic: N/A

    NASA Johnson Space Center is developing an active synthetic soil to grow plants in space as part of their regenerative life support system. The synthetic soil is zeolite based and slowly releases nutrients but unfortunately becomes acidic with time. The proposed research evaluates using natural and synthetic components to buffer soil pH within optimum ranges for plant growth. Objectives are to cha ...

    SBIR Phase II 1995 National Aeronautics and Space Administration
  9. Solid-State Lidar for Monitoring Turbulent Air Motion

    SBC: COHERENT TECHNOLOGIES, INC.            Topic: N/A

    Under a prior NASA Phase I, an analysis of a pulsed, 2 um solid- state lidar system has been carried out to evaluate its potential for precision wind velocity measurements. A preliminary design has been specified for an airborne instrument. The proposed second phase of that study is intended to develop and test an appropriate long coherence time-pulsed transceiver. The program proposed herein will ...

    SBIR Phase II 1995 National Aeronautics and Space Administration
  10. Aircraft Wake Tracking Analysis

    SBC: COHERENT TECHNOLOGIES, INC.            Topic: N/A

    NASA has recently begun a program to improve terminal area productivity (capacity) that will serve to simultaneously save airline operating costs and improve aviation safety. Reduction of aircraft spacing during instrument flight rules (IFR) conditions requires a thorough understanding of environmental effects on wake vortex transport and decay mechanisms. In the proposed program, existing algorit ...

    SBIR Phase II 1995 National Aeronautics and Space Administration

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