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POOR COMPLIANCE TO MEDICATION REGIMENS AND THE RESULTING INEFFECTIVENESS OF TREATMENT ARE MAJOR CONCERNS IN DRUG STUDIES AND IN SELF-ADMINISTRATION OF PRESCRIBED MEDICATION. ATA CORPORATION DEVELOPS AND MARKETS DEVICES THAT MONITOR COMPLIANCE AND IMPROVE COMPLIANCE THROUGH REMINDING AND GUIDING FUNCTIONS. IMPROVEMENT OF POOR COMPLIANCE IS PARTICULARLY IMPORTANT IN THE TREATMENT OF GLAUCOMA. IT IS ...

THE LONG-TERM OBJECTIVE OF THE PROPOSED WORK IS TO PROVIDE PHYSICIANS AND OTHERS IN THE FIELD OF PREVENTIVE HEALTH CARE DELIVERY WITH AN INEXPENSIVE AND RELIABLE BIOCHEMICAL TEST TO MEASURE PATIENTS' EXPOSURE TO TOBACCO SMOKE. AT PRESENT, A RELIABLE TEST OF THIS TYPE IS NOT AVAILABLE ON A COMMERCIAL BASIS. COTININE, A METABOLITE OF NICOTINE, HAS BEEN SELECTED AS THE PRODUCT TO MEASURE BECAUSE OF I ...

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THE LONG-TERM GOAL OF THIS APPLICATION IS TO DEVELOP DIMETHYLSUBERIMIDATE (DMS) AS AN ALTERNATIVE PULP THERAPY. FORMOCRESOL, THE DRUG MOST COMMONLY USED FOR TREATMENT OF CARIOUSLY EXPOSED PULPS OF THE PRIMARY DENTITION, IS TOXIC TO THE TREATED TISSUE, INDUCES ANTIGEN FORMATION AND SUBSEQUENT CHRONIC INFLAMMATION, IS RAPIDLY DISTRIBUTED SYSTEMICALLY, AND HAS MUTAGENIC POTENTIAL. FORMOCRESOL PULPOTO ...

THE NEW INTERFERENCE COLOR SLIDE PROPOSED FOR IMMUNOASSAYS PRODUCES THE DESIRED COLOR CHANGES IN A WET STATE. THIS TECHNIQUE WILL BRING ASSAYS CLOSER TO A ONE-STEP PROCESS THAN EXISTING TECHNOLOGY. WITHOUT THE RINSING AND DRYING STEPS, THE WET TECHNIQUE WILL BE SIMPLER AND FASTER THAN ELISA. THE ENTIRE ASSAY CAN BE CONTAINED INSIDE BE REFLECTED IN THE HANDLING TIME AND END COSTS OF THE TEST. PRELI ...

A NEW INSTRUMENT IS PROPOSED FOR THE STUDY OF MONOMOLECULAR ORGANIC FILMS. THIS INSTRUMENT CONSISTS OF AN IMAGING ELLIPSOMETER VIEWFINDER AND A ONE-SPOT THICKNESS-MEASURING PHOTOMETER VISIBILE IN THE VIEWFINDER. WITH THE VIEWFINDER,MONOMOLECULAR PROTEIN SPOTS COULD BE SEEN ON THE SURFACE OF A SLIDE, SO THAT SAMPLE HOMOGENEITY AND QUALITY COULD BE ASSESSED BEFORE THE PHOTOMETER IS USED. THE SIZE OF ...

A NOVEL CELL-SEPARATION METHOD UTILIZING OSCILLATING ELECTROMAGNETIC FIELDS WILL BE INVESTIGATED. THE PRINCIPLE OF SEPARATION LIES IN THE POLARIZABLE NATURE OF THE LIVE CELLS IN THE ELECTRIC FIELD. IN THIS METHOD, A SUSPENSION OF HETEROGENEOUS CELL MIXTURE IS SUBJECTED TO ELECTROMAGNETIC FIELDS. THEORETICAL CALCULATION OF A MODEL SYSTEM PREDICTED THAT UNIDIRECTIONAL CELL MIGRATION OCCURS. THE VELO ...

BIOTECHNOLOGY ASSOCIATES, INC. WILL DEVELOP SURFACE COATINGS COMPOSED OF FILMS OF POLYMERIZED LIPIDS THAT WILL BE NONTHROMBOGENIC AND NONADHESIVE FOR CELLS. THUS THEY MAY PROVIDE USEFUL BIOCOMPATIBLE COATINGS FOR BIOMEDICAL DEVICES. LIPID POLYMER FILMS WILL ALSO BE MODIFIED BY COUPLING OF ADHESION PROTEINS OR PEPTIDES TO PROVIDE SURFACES WITH CONTROLLED CELL ADHESION PROPERTIES IN THE ABSENCE OF S ...

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