Award Data

The overall goal of this project, in response to SBIR topic DHP12-016, is to refine and validate in an IACOC approved porcine study a novel easily deployed device to immediately treat severe facial burns in order to prevent infection and wound progression

Timely management and closure of burn wounds are critical for proper emergency care and the assurance of positive outcomes for the warfighter. Current technologies rely on reagents that cannot respond effectively to the different classes of pathogens that

In this Phase I program, Fabrico Technology, Professor Leonid Bunegin of the University of Texas Health Science Center at San Antonio (UTHSC-SA), and Dr. Rocco Armonda, Director, Neuroendovascular Surgery and Neurotrauma, MedStar-Georgetown University Hos

Incidences of infectious disease pose serious threats to armed forces worldwide, risking the success of critical operations and can be responsible for the deaths of Warfighters. Current approaches attempt to reduce severity of disease impact to operational forces by detecting, monitoring, and treating infected personnel after exposure, but this does not effectively maintain and sustain force healt ...

Integrated Clinical Environments (ICE) rely heavily on medical devices that need to be protected from security threats without compromising patient health and safety. There is a need to assess clinical workflow configurations in terms of security, usability, and efficiency. Currently, each medical device has its own security controls. Access to multiple devices in the integrated environment requir ...

TDAs proposes to develop a novel RF heating process for rewarming cryogenically preserved tissues and organs. TDAs approach is to optimize the RF frequency and power, along with the chemical composition, size and morphology of infused nanoparticles so that they heat tissue samples rapidly and uniformly. In this manner, the cryoprotectant solutions pass from the vitrified state to the liquid stat ...

KBSI proposes to design and develop a Data Integration and Predictive Analysis System (IPAS) for the prediction of incidents of human infectious diseases. IPAS will utilize innovative collection of data from open data sources, veterinary and medical professionals, and public observations, together with data cleaning, harmonization, spatio-temporal pattern extraction, factor analysis, and predicti ...

Intraocular surgery is usually performed under the stereoscopic guidance using a surgical microscope. However, when the optical clarity of the cornea is severely compromised, precluding visualization of the retina and other intraocular anatomy, intraocular surgery becomes very difficult and with increased risk of irreversible error. Minimally-invasive needle-size endoscopic tools are available, bu ...

About 40% of trauma-related deaths are related to rapid onset of coagulopathy and the vast majority of trauma patients are coagulopathic at the time of death. Lynntech proposes to develop a novel, easy-to-use and cost effective device for simultaneous quantitative real-time detection of multiple proteins involved in the hemostatic mechanism, using human unprocessed whole blood as the input sample. ...

Bioassays employed to evaluate the diverse range of biomarkers associated with organ injury are time-consuming, costly and require multiple instruments/testing formats to reach a diagnosis (i.e. fluorescence-based capture, ELISAs, PCR, etc.). Individually, these platforms are incapable of predicting the onset of irreversible organ tissue injury (e.g. kidney, liver, heart and lung). If a single mul ...