Award Data

THE PURPOSE OF THIS STUDY IS THREEFOLD: PART I WILL LAST APPROXIMATELY THREE MONTHS; THE GOAL OF THIS SEGMENT WILL BE TO DEVELOP ALL COMPONENTS REQUIRED FOR A SELF-MANAGEMENT PROGRAM FOR ALL ASTHMATIC PATIENTS. THIS WILL ENTAIL, IN PART, REFINING AND VIDEOTAPING PORTIONS OF A PROGRAM WITH PROVEN EFFICIENCY, WHEEZERS ANONYMOUS. IN ADDITION, RELIABILITY AND VALIDITY OF PAPER-AND-PENCIL INSTRUMENTS U ...

N/A

N/A

POOR COMPLIANCE TO MEDICATION REGIMENS AND THE RESULTING INEFFECTIVENESS OF TREATMENT ARE MAJOR CONCERNS IN DRUG STUDIES AND IN SELF-ADMINISTRATION OF PRESCRIBED MEDICATION. ATA CORPORATION DEVELOPS AND MARKETS DEVICES THAT MONITOR COMPLIANCE AND IMPROVE COMPLIANCE THROUGH REMINDING AND GUIDING FUNCTIONS. IMPROVEMENT OF POOR COMPLIANCE IS PARTICULARLY IMPORTANT IN THE TREATMENT OF GLAUCOMA. IT IS ...

THE LONG-TERM GOSL OF THIS RESEARCH IS TO CONSTRUCT AND EVALUATE A NONINVASIVE DEVICE THAT WILL ASSESS THE FUNCTIONAL INTEGRITY OF HYPOTHERMIC PERFUSED KIDNEYS PRIOR TO TRANSPLANT. THE DEVICE IS BASED ON MEASUREMENTS OF CHANGES IN MITOCHONDRIAL ELECTRON-TRANSPORT PROTEIN-OXIDATION STATES IN THE KIDNEY CORTEX. THESE CHANGES CAN BE MEASURED SPECTROPHOTOMETRICALLY AND WILL BE IMAGED AT THE SURFACE OF ...

N/A

THE NEW INTERFERENCE COLOR SLIDE PROPOSED FOR IMMUNOASSAYS PRODUCES THE DESIRED COLOR CHANGES IN A WET STATE. THIS TECHNIQUE WILL BRING ASSAYS CLOSER TO A ONE-STEP PROCESS THAN EXISTING TECHNOLOGY. WITHOUT THE RINSING AND DRYING STEPS, THE WET TECHNIQUE WILL BE SIMPLER AND FASTER THAN ELISA. THE ENTIRE ASSAY CAN BE CONTAINED INSIDE BE REFLECTED IN THE HANDLING TIME AND END COSTS OF THE TEST. PRELI ...

A NEW INSTRUMENT IS PROPOSED FOR THE STUDY OF MONOMOLECULAR ORGANIC FILMS. THIS INSTRUMENT CONSISTS OF AN IMAGING ELLIPSOMETER VIEWFINDER AND A ONE-SPOT THICKNESS-MEASURING PHOTOMETER VISIBILE IN THE VIEWFINDER. WITH THE VIEWFINDER,MONOMOLECULAR PROTEIN SPOTS COULD BE SEEN ON THE SURFACE OF A SLIDE, SO THAT SAMPLE HOMOGENEITY AND QUALITY COULD BE ASSESSED BEFORE THE PHOTOMETER IS USED. THE SIZE OF ...

A NOVEL CELL-SEPARATION METHOD UTILIZING OSCILLATING ELECTROMAGNETIC FIELDS WILL BE INVESTIGATED. THE PRINCIPLE OF SEPARATION LIES IN THE POLARIZABLE NATURE OF THE LIVE CELLS IN THE ELECTRIC FIELD. IN THIS METHOD, A SUSPENSION OF HETEROGENEOUS CELL MIXTURE IS SUBJECTED TO ELECTROMAGNETIC FIELDS. THEORETICAL CALCULATION OF A MODEL SYSTEM PREDICTED THAT UNIDIRECTIONAL CELL MIGRATION OCCURS. THE VELO ...

RECENT IMPROVEMENTS IN IMPLANTABLE PHYSIOLOGICAL TRANSDUCER TECHNOLOGY AND THE AVAILABILITY OF LOW-COST COMPUTATIONAL POWER HAVE GREATLY INCREASED INTEREST IN THE AUTOMATED CONTROL OF PHYSIOLOGICAL PARAMETERS IN THE RESEARCH LABORATORY AND IN CLINICAL THERAPY. THE OBJECTIVE OF THIS RESEARCH IS TO DEVELOP AND EVALUATE SAFE AND EFFECTIVE ADAPTIVE CONTROL SOFTWARE FOR THE AUTOMATIC REGULATION OF THER ...