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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. N/A

    SBC: ABRATECH CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  2. N/A

    SBC: ABRATECH CORPORATION            Topic: N/A

    N/A

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  3. ABR train-block detection of small acoustic neuromas

    SBC: ABRATECH CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The evoked response called the ABR (Auditory Brainstem Response) is affected by nerve compression by acoustic neuromas, but is not presently sensitive enough to detect small tumors. If the ABR could be used to detect tumors, it would reduce overall medical costs and also provide a means to judge rate of tumor progression. This project proposes to improve the s ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  4. In vivo transcription factor DNA binding analysis

    SBC: ACTIVE MOTIF, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Currently, there exist a number of methods for the study of transcription factors and gene-promoter activity. These include reporter gene assays, gel shift assays, and expression-profiling methods such as microarray analysis and SAGE. These methods are well established and have been used to generate a wealth of information. Accordingly, there are many commercia ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  5. Novel conformation-based nuclear receptor activity assay

    SBC: ACTIVE MOTIF, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this proposal is the development of novel methods for the study of the Class II Nuclear Receptors Thyroid hormone receptor (TR), Retinoic Acid Receptor (RAR), and Vitamin D3 Receptor (VDR). Like other members of the nuclear receptor superfamily, these transcription factors directly activate or repress target genes by binding to DNA response ele ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  6. Activity-based Proteomics for Toxicological Analysis

    SBC: ACTIVX BIOSCIENCES            Topic: N/A

    DESCRIPTION (provided by applicant): ActivX Biosciences (ActivX) will develop and validate a novel toxicoproteomics platform to correlate changes in protein activity with compound toxicology. This platform uses fluorescent chemical probes to interrogate catalytically active proteins related by super-family derived from any biological sample. Alterations in protein activity are expected to be mor ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  7. An Improved Prosthetic Bioactuator

    SBC: ADA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Innovations in battery technology and microelectronics are now finding wide acceptance in the design of new prosthetic and orthotic appliances, while the actuators used to produce motion and force in these devices remain essentially unimproved. The overall goal of this multi-phase, expanded SBIR project is to adapt a new class of "active" materials--developed t ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  8. Powered Orthoses for Augmenting Upper Limb Functionally

    SBC: ADA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): According to the U.S. Bureau of the Census, approximately 7.7 million people over the age of 15 report they are unable to lift or carry even 10 pounds with their arms because of neuromuscular impairments. Extensive research suggests that "powered orthoses" could provide great benefit to many of these individuals. Comprised essentially of an orthotic brace fitt ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  9. Binaural Assessment Instrument for Cochlear Implants

    SBC: ADVANCED BIONICS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): The primary purpose of the proposed research is to develop, validate, implement, and norm a practical binaural assessment protocol that can be used clinically with bilateral cochlear implant patients. The protocol will be implemented in a computerized instrument to be developed in the course of the project. Binaural assessment of a cochlear implant patient will ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  10. Biobehavioral Measurements of Alertness in Sleep Apnea

    SBC: ADVANCED BRAIN MONITORING, INC.            Topic: N/A

    DESCRIPTION (Applicant's abstract): The proposed research evaluates the efficacy of the Alertness Profiling (AP) System as a method for objectively quantifying alertness in Sleep Apnea (SA) patients. The AP simultaneously measures electroencephalographic (EEG) indices and performance during vigilance, attention and memory tests. Combining EED and neurobehavioral assessment in a one-hour session, t ...

    SBIR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
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