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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. IMPROVED HYPOGLYCEMIA RESCUE DEVICE

    SBC: Xeris Pharmaceuticals, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this program is to develop of a clinical prototype, semi-solid drug formulation and auto-injector pen that deliver microliter volumes of a glucagon dose without reconstitution for hypoglycemic emergencies. To assess the feasibility of this objective, it is necessary to first demonstrate that glucagon can be formulated into an ultra- concentrate ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  2. Brain-activity during sedation predicting post-sedation explicit-memory

    SBC: ABRATECH CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): This project will study electrical brain-activity measures that may be able to indicate whether or not long-term memory is occurring, under light sedation. The goal is to develop a brain-monitor to be used in the operating room to ascertain if a patient's level of anesthesia has become too light, such that the patient can experience pain, and understand what is ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  3. A Disposable Amperometric Lithium Ion-selective Electrode for Home Testing

    SBC: ADA TECHNOLOGIES, INC.            Topic: N/A

    Not Available

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  4. A Next-Generation Split Hook Prehensor with Enhanced Grasp Functionality

    SBC: ADA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Owing to certain intrinsic advantages, a surprisingly large number of upper-extremity amputees prefer simple cable operated prostheses and split hook terminal devices for many activities. For disadvantaged amputees in the United States and in developing countries, such systems often present the only viable restorative option. ADA Technologies and its supportin ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  5. A Low-Cost Upper-Extremity Prosthetic Interface

    SBC: ADA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Remarkable advances in signal processing techniques, materials sciences, battery technologies, and computer-aided design and computer-aided manufacturing (CAD/CAM) processes have led to significant developments in assistive technologies. Coordinated research and commercialization have dramatically increased prosthetic function, utility, personalization, comfor ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  6. Novel 3-dimensional (3-D) platform for high-throughput glycomics analysis

    SBC: ADA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Glycan (carbohydrate microarrays), carrying tens or hundreds of different sugars that are immobilized on solid surfaces in a spatially discrete pattern, possess a wide variety of potential applications in glycomics including rapid determination of the binding profile of carbohydrate-binding proteins, detection of specific antibodies for the diagnosis of disease ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  7. Identification of Anti-HIV Lead Compounds Targeting Rev

    SBC: ADVANCED GENETIC SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There is a significant need for novel HIV therapies given the emergence of viruses resistant to existing drug regimens. The Rev-RRE protein-RNA interaction in HIV plays an essential role in the transport of viral mRNA from the nucleus to the cytoplasm where it can be translated or packaged. In preliminary work, two distinct assays targeting the HIV Rev protein ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  8. Characterization of Cellular Proteins Involved in HIV Infection

    SBC: ZIRUS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Important advances have been made in the treatment of viral infections over the last two decades, especially with the extensive availability of drugs to treat HIV infection, but there is a need to develop new drugs particularly with the challenges facing HIV vaccine development and the propensity to develop drug resistance. With FDA approval in 2007 of the firs ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  9. Discovery of inhibitors of ALK for the treatment of cancer

    SBC: Zenobia Therapeutics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Our aim is to discover novel safety assessment candidates (pre-clinical compounds) for the treatment of cancer by targeting the receptor tyrosine kinase (RTK), anaplastic lymphoma kinase (ALK). It is now proven that ALK has a widespread pathogenic involvement in cancer through the expression of either constitutively activated fusion proteins or activating mutat ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  10. Cardiac Cryoablation Catheter

    SBC: ADVANCED REFRIGERATION TECHNOLOGIES, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Atrial fibrillation (AF) is the most frequent arrhythmia encountered in clinical practice and is the most common arrhythmia necessitating hospital admission. Nearly three million people in the U.S. have Atrial Fibrillation. Americans over 40 have a one in four lifetime risk of developing Atrial Fibrillation. Currently there is only one practical treatment, pulm ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
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