Award Data

DESCRIPTION (provided by applicant): WAYFINDER: A Cognitive Aid for Independent Transportation ABSTRACT Transportation and mobility have long been areas of great dependency for individuals with intellectual disabilities, such as mental retardation. Few ind ividuals with intellectual disabilities obtain drivers licenses. Other typical modes of transit, such as taxi service, are prohibitive due to c ...

DESCRIPTION (provided by applicant): We propose to develop compact magnetic resonance imaging (MRI) systems for imaging lungs as well as other soft tissue in live laboratory animals based on permanent magnets that are reasonably priced and easy to maintain. Such imagers will benefit public health by improving laboratory animal research. Unlike other soft tissues, lungs are difficult to image with ...

DESCRIPTION (provided by applicant): Proposed is the development of manufacturing processes for electrostrictive arrays allowing for real-time ultrasound volumetric imaging. To date, the commercial development of 2D transducer arrays having thousands of array elements has been significantly limited due to manufacturing inefficiencies, transducer element sensitivity; the complexity associated with ...

DESCRIPTION (provided by applicant): Age-related macular degeneration (AMD) is the major cause of irreversible loss of vision in the adult population. AMD can be classified into the "dry" form and the "wet" form. The dry form involves apoptotic changes in the photoreceptor cells or the retinal pigment epithelium (RPE) cells underlying the central retina (macula). The dry form can progress to the w ...

DESCRIPTION (provided by applicant): The average person in the U.S. contains detectable levels of more than 100 industrial compounds, pollutants, and chemicals, but predicting the relative risk of this exposure, especially over time, is challenging (US CDC, 2003). Successful development and commercialization of next-generation, low-cost, high-performance technology for predicting compound toxicity ...

DESCRIPTION (provided by applicant): Neural prosthetic devices are artificial extensions to the body that restore or supplement nervous system function that was lost during disease or injury. Particular success has been realized in the cochlear prostheses development. In contemporary cochlear implants, however, the injected electric current is spread widely along the scala tympani and across turns ...

DESCRIPTION (provided by applicant): Carbohydrate functionalized nanoparticles, i.e., the glyco-nanoparticles, have wide application ranging from studies of carbohydrate-protein interactions, in vivo cell imaging, biolabeling, cancer diagnostics, and to vaccine discovery. However, in comparison with DNA and protein functionalized nanoparticles, the development of glyco-nanoparticle has been left f ...

DESCRIPTION (provided by applicant): Glycomics is an emerging field that focuses on studying the interactions of carbohydrates with other biopolymers, particularly proteins, to gain a better understanding of the roles of carbohydrates in biological processes. Carbohydrate microarray technologies represent a new development at the frontier of glycomics. Microarrays of carbohydrates (glycoconjugates ...

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DESCRIPTION (provided by applicant): Conventional body-powered assistive appliances intended to help children having upper limb deficiencies have proven inadequate for some activities, most notably play. The critical component in these systems that contributes grasp functionality, called a prehensor or terminal device, must strike a balance between functionality for activities children wish to ac ...