List

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Coated Scaffolds for Intra-Operative Protein Incorporation and Controlled Release

    SBC: TISSUE REGENERATION SYSTEMS, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): The purpose of the proposal is to develop medical device coatings that bind and release therapeutic proteins, particularly growth factors. Specifically, we propose to systematically optimize and control growth factor binding and release using protocols that can be translated to the operating room. Bone fracture repair and reconstruction of critical-sized defect ...

    SBIR Phase I 2011 Department of Health and Human Services
  2. Compliant Shape Memory Polymer Device for Meniscal Repair

    SBC: MEDSHAPE, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): The objective of this project is to develop compliant meniscal repair devices based on shape memory polymers. The repair device will be inserted in a less invasive temporary shape and then triggered to expand into its permanent functional shape. Meniscus repair represents an increasingly common and critical soft-tissue based orthopedic procedure. Approximately ...

    SBIR Phase I 2011 Department of Health and Human Services
  3. VerOFy: A New Tool to Improve Productivity and Reduce Costs for Stress Research

    SBC: OASIS DIAGNOSTICS CORPORATION            Topic: NCCAM

    DESCRIPTION (provided by applicant): This Phase 1 NIH SBIR proposal is for support of an interdisciplinary program involving the Oasis Diagnostics(R) Corporation, Madison Biodiagnostics, LLC, and the University of New Orleans who seek to collaboratively demonstrate an innovative saliva collection and analysis system (VerOFy(R)) for measurement of cortisol levels at the point of sampling for measur ...

    SBIR Phase I 2011 Department of Health and Human Services
  4. Reducing Complement Inhibition to Treat Leukemia and Lymphoma

    SBC: Compliment Corporation            Topic: NCI

    DESCRIPTION (provided by applicant): The funding of the application will yield safety and efficacy data on a new combination cancer therapy for leukemia and lymphomas. Monoclonal antibodies (mAbs) have emerged as a class of novel oncology therapeutics. Weare developing a molecule that can improve the therapeutic effects of mAbs by: 1) increasing the sensitivity of cancers to treatment 2) unmaskin ...

    SBIR Phase I 2011 Department of Health and Human Services
  5. Analgesics Targeting TRPA1 for Treatment of Chronic Pain

    SBC: ALGOMEDIX, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): Title: Analgesics Targeting TRPA1 for Treatment of Chronic Pain Abstract An effective treatment for chronic pain that is devoid of both addictive potential and abuse liability is a major unmet need in medicine today. These limitations drive the need for novel treatment options based on new molecular mechanisms. Our goal is to identify and develop a novel, ...

    SBIR Phase I 2011 Department of Health and Human Services
  6. Training Oral Hygiene Habits with a Game

    SBC: Big Fun Development Corp            Topic: NIDCR

    DESCRIPTION (provided by applicant): An epidemic of dental disease afflicts the United States. Twenty-nine percent of Americans have untreated caries. Methods to prevent this disease are well understood. Application of these methods presents a challenge tothe public health system. Most ongoing public health efforts address the problem at one of three points: (1) use of fluoride to remineralize tee ...

    SBIR Phase I 2011 Department of Health and Human Services
  7. Therapeutic Vaccine for HIV/HPV-associated Oropharyngeal and Tonsillar Malignanci

    SBC: Etubics Corporation            Topic: NIDCR

    DESCRIPTION (provided by applicant): The objective of this project is to develop a therapeutic strategy for H V-associated malignancy based on the role of HPV in the pathogenesis. HPV related cancers express the E6/E7 oncoproteins of HPV that are ideal targets for immune inducing vaccines. We will develop a vaccine based upon a novel adenovirus serotype-S vector (Ads) platform with unique and addi ...

    SBIR Phase I 2011 Department of Health and Human Services
  8. Advanced Hypoglycemia Prevention Capabilities in Fuzzy Logic Artificial Pancreas

    SBC: DOSE SAFETY INC            Topic: NIDDK

    DESCRIPTION (provided by applicant): The ultimate technical objective of this research is the development of an Artificial Pancreas (AP) controller that improves metabolic control and decreases glycemic excursions by robustly preventing hypoglycemic episodes. Proportional-integral-derivative control (PID) and model predictive control (MPC) have been widely considered to be promising candidate for ...

    SBIR Phase I 2011 Department of Health and Human Services
  9. Real-time Threshold Exposure Monitor for Particulate Matter and Volatile Organic

    SBC: ENERTECHNIX, INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): This Phase I project will evaluate the feasibility of developing an exposure monitor for particles in the PM2.5 and PM10 size ranges, and for volatile organic compounds (VOCs), at threshold levels for children's healtheffects. The proposed device will use aerodynamic particle properties for concentration and separation into discrete size bins and will enab ...

    SBIR Phase I 2011 Department of Health and Human Services
  10. An Integrated Cross-Correlative Environmental Specimen Holder Platform for Optica

    SBC: Hummingbird Precision Machine Inc.            Topic: NIGMS

    DESCRIPTION (provided by applicant): To gain a comprehensive understanding of cellular structures and function, correlative light and electron microscopy has been widely utilized to facilitate the acquisition of both macroscopic view of the whole organismand the localization of single molecules or macromolecular complexes. However, current correlative microscopy solutions require extensive sample ...

    SBIR Phase I 2011 Department of Health and Human Services

Agency Micro-sites

SBA logo
Department of Agriculture logo
Department of Commerce logo
Department of Defense logo
Department of Education logo
Department of Energy logo
Department of Health and Human Services logo
Department of Homeland Security logo
Department of Transportation logo
Environmental Protection Agency logo
National Aeronautics and Space Administration logo
National Science Foundation logo
US Flag An Official Website of the United States Government