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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Developing pan lyssavirus beta actin real time RT PCR assays for rabies diagnostics

    SBC: CyanVac LLC            Topic: ODCDC

    Rabies is a deadly zoonotic disease caused by rabies virusRABVand other lyssavirusesAnnuallyrabies causes approximatelyhuman deaths worldwideThe only widely accepted diagnostic test is the direct fluorescent antibodyDFAtestWhile rapid and sensitivethe DFA test requires expensivehighquality reagents and equipmentalong with trained diagnosticiansThese factors present economic and logistical barriers ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. Topic 376: Non-Invasive Subtyping of Aggressive Tumor and Its Environment- Moonshot

    SBC: INLIGHTA BIOSCIENCES L.L.C.            Topic: NCI

    Generation of high-resolution 3D anatomic and dynamic images without exposing patients to ionizing radiation renders MRI the preferred imaging modality for the detection of tumor extent and treatment response to neo-adjuvant and adjuvant medical therapies. The goal of this proposal is to develop a non-invasive, in vivo imaging-based platform that can repeatedly generate three-dimensional molecular ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Media-based youth e-cig prevention toolkit for community-based organizations

    SBC: KDH Research And Communication, Inc.            Topic: NIDA

    KDH Research and CommunicationKDHRCsubmits this Fast Track SBIR proposal to develop and evaluate AVOIDAnti Vaping Online Information Disseminationa media based online toolkit to support community based organizationsCBOprevention programming against youth e cigarettee ciguseYouth e cig usealso known asvapingis a rapidly growing public health threatwith use among high school students tripling fromto ...

    SBIR Phase II 2018 Department of Health and Human Services
  4. RECAL:A New Tool for Disease Detection and Biomolecular Imaging

    SBC: Photon Biosciences LLC            Topic: 400

    Project SummaryAbstract We envision developing a new ultrasensitive detection platform that combines a recombinant protein with a unique imaging media that results in a luminescent protein that is non bleaching and non blinkingThe excitation and emission wavelengths of this protein can be tuned with the choice of imaging media and span much of the visible and near infrared regions of the electroma ...

    SBIR Phase I 2018 Department of Health and Human Services
  5. Effect of Repeated Administration of G-CSF on Hot Flashes and Other Vasomotor Symptoms of Menopause

    SBC: MENOGENIX, INC.            Topic: NIA

    One of the most common and distressing symptoms of menopause are hot flashesHot flashes and related symptoms represent a significant unmetworldwidehealthcare neednot only in women after surgical or natural menopausebut also in breast and prostate cancer patients undergoing hormone suppression or ablationHot flashes occur inof women undergoing natural menopause and approximatelymillion individuals ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Tools for drug efficacy studies in perfused tissue models

    SBC: Lena Biosciences, Inc.            Topic: 100

    Organ on a chip tools that recapitulate human biologyphysiology and pathology are urgently needed in applied science research and drug testing to expedite discoveries while reducing research costs and animal sacrificeUnfortunatelymost products incorporating circulation mimicking perfusion are too complicated for researchers to useincompatible with many protocols and readsand low throughputOur goal ...

    SBIR Phase II 2018 Department of Health and Human Services
  7. Online course to prepare promotores to support low-income Latino parents of children with special healthcare needs

    SBC: KDH Research And Communication, Inc.            Topic: NIMHD

    KDH Research andampCommunicationKDHRCsubmits this Fast Track SBIR proposal to developimplementand rigorously evaluate a culturally competentonline professional development course to prepare promotores to support low income Latino parents of children with special health care needsCSHCNas they navigate the education and health care systemsCSHCN experience poorer healthpsychosocialand academic outcom ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Real-Time Salivary Testosterone and Extension to Mobile Application and Multiple Biomarker Quantification Capability

    SBC: OASIS DIAGNOSTICS CORPORATION            Topic: NIDA

    Program Director Principal InvestigatorLastFirstMiddleSloweyPaul DAbstract This phase I NIH SBIR proposal seeks support for an interdisciplinary partnership between Oasis Diagnosticsand Iowa State University who collaboratively seek to develop a novel tool that can measure and quantify levels of the sex hormone testosterone in saliva within minutes of collectionVerOFytestosteroneThe FDA has urged ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Development of an alpha-conotoxin RgIA analog as a novel, non-opioid therapeutic for chronic neuropathic pain

    SBC: KINETA, INC.            Topic: NIDA

    PROJECT SUMMARY The objective of this SBIR Phase I application is to select an optimized lead analog ofconotoxin RgIA to develop as a uniquenon opioid therapeutic for chronic neuropathic painRgIAa peptide derived from the predatory marine cone snail Conus regiusis an inhibitor of thenicotinic acetylcholine receptornAChRa novel genetically validated pain targetOur current lead candidateKCPpotently ...

    SBIR Phase I 2018 Department of Health and Human Services
  10. High-specificity affinity reagents for the detection of glycan sialylation

    SBC: GLYCOSENSORS AND DIAGNOSTICS, LLC            Topic: 300

    PROJECT SUMMARY Glycans have several distinct properties that make them potential disease biomarkersFirstlytheir location on cell surfaces makes them the first point of contact for cellular interactionsand thus they are crucial in the control of normal metabolic processesSecondlycell surface molecules are strategically exposed for surveillance by the immune systemwhere they may serve as immune rec ...

    SBIR Phase II 2018 Department of Health and Human Services

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