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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Physics and Physiology Based Human Body Model of Blast Injury and Protection

    SBC: CFD Research Corporation            Topic: DHP13010

    The vast majority of injuries in recent military conflicts have been inflicted by improvised explosive devices (IEDs) causing brain, extremities and genital-urinary injuries. Advanced computational models of IED blast physics and human body injury biomech

    SBIR Phase II 2015 Department of DefenseDefense Health Program
  2. Improving Wound Healing by Combating Multi-Drug Resistant Pathogens Using Small Molecule Antimicrobials

    SBC: TECHULON, INC.            Topic: DHP15007

    Techulon has developed a platform based on peptide-peptide nucleic acids (PPNAs) molecules that are effective as antimicrobial compounds against multi-drug reisistant pathogens. Techulons targeted approach uses informatic algorithms applied towards an organisms genome to identify targets that will disrupt essential biological functions. The proposed Phase I project will focus on developing a new g ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  3. Novel Rewarming Technique for Cyropreserved Tissue

    SBC: TDA Research, Inc.            Topic: DHP15014

    TDAs proposes to develop a novel RF heating process for rewarming cryogenically preserved tissues and organs. TDAs approach is to optimize the RF frequency and power, along with the chemical composition, size and morphology of infused nanoparticles so that they heat tissue samples rapidly and uniformly. In this manner, the cryoprotectant solutions pass from the vitrified state to the liquid stat ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  4. Systems Biology Based Tools for Modeling Platelet Storage Lesion for Optimal Blood Transfusions

    SBC: CFD Research Corporation            Topic: DHP15011

    Trauma is the leading cause of death in civilian and military environments and acute hemorrhage contributes to a large portion of these fatalities. Recent experience from Iraq and Afghanistan has demonstrated the crucial role of blood products in the care of critically injured soldiers. Unlike plasma and red blood cells, which can be cold stored for longer time periods, platelets can be safely sto ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  5. Virtual Medical Concierge Application

    SBC: ADAPTIVE METHODS, INC.            Topic: DHP15003

    The use of the Walter Reed National Military Medical Center (WRNMMC) can be difficult for patients and visitors to use due to the size and complexity of the facility. The current a kiosk concierge system cannot offer turn-by-turn facility navigation. This proposal seeks to design a combined indoor/outdoor navigation service to aid using and locating services and people in the WRNMMC facility. ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  6. A rapid and high-throughput microfluidic stem cell analyzer

    SBC: CFD Research Corporation            Topic: OSD11H14

    Current methods for stem cell isolation are time-consuming, costly, and labor-intensive, and ill-suited for point of care applications. To overcome these limitations, we propose to develop and demonstrate a high-throughput, non-invasive, microfluidic stem cell analyzer to enable a rapid isolation of high-quality stem cell products from clinically relevant samples. Our technology enables significan ...

    SBIR Phase II 2015 Department of DefenseDefense Health Program
  7. Technologies for Treating Cartilage Tissue Loss Following Traumatic Injury

    SBC: Spheringenics, Inc.            Topic: OSD10H04

    Traumatic injuries to the head and neck region comprise as much as 30 percent of all combat injuries observed today. These injuries often involve multiple tissues including dermal, muscle, cartilage and bone. This work aims to address this critical need by treating a composite tissue injury model in the ear. We will use an alginate microbead cell delivery system

    SBIR Phase II 2015 Department of DefenseDefense Health Program
  8. A NANOeSPRi-based IVD Assay for Multiple Organ Injury

    SBC: Luna Innovations Incorporated            Topic: DHP14005

    Major organ injuries such as liver, kidney, heart and lung injuries can lead to high morbidity and mortality in critically ill patients. Advanced noninvasive testing with high sensitivity and specificity is needed to detect specific organ injury particularly at early stages. Current techniques such as PCR, MS, absorption-based assays, ELISA and microfluidic-Luminex, cannot meet such requirements. ...

    SBIR Phase II 2015 Department of DefenseDefense Health Program
  9. A Point-of-Care Device for Diagnosis of Platelet Injury in Trauma Patients

    SBC: HEMOSONICS            Topic: DHP13013

    HemoSonics LLC is developing an easy to use and easy to interpret diagnostic device to rapidly identify diffuse coagulopathies in order to guide proper and evidence-based interventions. The management of diffuse coagulopathies is extremely important in military medicine as these conditions represent a significant source of combat morbidity and mortality. HemoSonics device is based on sonorheome ...

    SBIR Phase II 2015 Department of DefenseDefense Health Program
  10. A Neck Injury Assessment Tool

    SBC: CFD Research Corporation            Topic: DHP13009

    The overall objective of the proposed project is to develop new injury criteria, model based risk assessment methodology, and a software tool to assess neck injury risk from head supported mass (HSM) loading. Based on the foundation of Phase I feasibility studies, the proposed Phase II work will focus on model enhancement, extension and validation, risk assessment, and software integration and tes ...

    SBIR Phase II 2015 Department of DefenseDefense Health Program

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