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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Low-Cost Physical Models of Proteins

    SBC: 3D Molecular Designs, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to develop the technology needed to produce accurate, low-cost physical models of proteins and other molecular structures by an injection molding approach. Two different technical innovations are required to make this possible. First, new software will be created to allow the unfolding of the complex geometry of a protein into a col ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Goblet Cell Stimulation Via Electric Charge Flux & Field

    SBC: ADA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Keratoconjunctivitus sicca (KCS), or dry eye, is a prevalent disease affecting an estimated one in five adults to varying degrees. Of Americans over the age of 65, some 4.3 million persons report tear film deficiencies, and certain diseases put patients at increased risk for the disease, including diabetes, lupus, arthritis, leukemia, fibromyalgia, acne rosace ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Collective Simulation Framework for Health Science Educa

    SBC: Agentsheets, Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Science apathy is growing at the K-12 education level, and represents an alarming development with potentially devastating consequences at individual, societal and economic levels. Surprisingly, this student apathy is increasing while the general public reads record numbers of popular science books and watches increasing amounts of science TV programming. In sp ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Atomic Layer Deposition on Particles for Nanoenergetic, Ferroelectric Capacitor and Thermal Management Applications

    SBC: ALD NANOSOLUTIONS, INC            Topic: AF02T007

    High performance energetic materials are based on inorganic thermite mixtures such as MoO3/Al or organic compounds such as RDX. Future developments in explosives are dependent on the fabrication of nanoscale materials and composite mixtures that display higher energy release rates. The ability to tailor composite materials precisely at the nanoscale by fabricating multilayer component particles ...

    STTR Phase II 2005 Department of DefenseAir Force
  5. Suspension arrays detection/quantification of antibodies

    SBC: ALPHA UNIVERSE LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In modern medicine and science there is a growing need for the ability to profile composition of such bodily fluids as serum and saliva. Microarray chip technology has potential for delivering such ability. This technology has already changed pharmaceutical research. So far, however, this technology has not been used extensively in protein-focused studies. The ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Approach for amplification of molecular signals

    SBC: ALPHA UNIVERSE LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Antibody-based detection systems have been used for years in clinical diagnostics and environmental monitoring for the detection and identification of pathogenic agents. Recent advances in the field of low-level antigen detection utilize the DNA polymerase-mediated signal amplification approach that provides a substantial enhancement in detection sensitivity ov ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Portable E-beam Pumped UV/X-ray Bio-decontamination System

    SBC: ASTRALUX, INC.            Topic: AF04004

    Biological warfare agents pose a grave threat to the United States, as events of the last few years have shown. The malicious delivery of Bacillus anthracis spores to government and private-sector buildings through the U.S. mail system in 2001, was a prime example. The U.S. Armed Forces currently rely on three outdated biodecontamination solutions, which have been used over the last 40 years: ...

    SBIR Phase II 2005 Department of DefenseAir Force
  8. Extremely Stable and Bright Periphylla Luciferase

    SBC: Avidity, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Luciferases have become invaluable detection tools in molecular biology and other fields. Their utility is imited by their physical liability. The currently available luciferases are sensitive to extremes of temperature and pH, which precludes their use as detectors in applications such as the polymerase chain reaction. Recently, a luciferase from the jellyfis ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Miniature sternal skin-attached hot flash recorder

    SBC: BAHR MANAGEMENT, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The characteristics of existing sternal skin conductance monitors that hinder use under ambulatory conditions and for long tern data collection are that they are too bulky to be cosmetically acceptable, have distracting wires, and weigh too much. We propose to characterize hot flashes by measuring the frequency, timing, and the amplitude of hot flashes using st ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Fluorescent HTS Assays for Human Sulfotransferases

    SBC: Bellbrook Labs, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase II proposal is for a collaborative effort between Dr. Richard Weinshilboum of the Mayo Institute and BellBrook Labs, LLC to translate basic pharmacogenetics research on conjugative drug metabolizing enzymes into molecular screening assays that can be applied in preclinical drug development. Drug metabolism problems such as drug interactions and produ ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
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