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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Device for Ultra-Rapid Non-Pharmacologic Ocular Anesthesia

    SBC: Irenix Medical, Inc.            Topic: NEI

    PROJECT SUMMARY / ABSTRACTThe objective of this Phase II proposal is to further develop a novel device for ocular anesthesia based on thermo-electric cooling. Intravitreal injection therapy (IVT) is one of the most commonly performed procedures in all of medicine, with approximately 7 million injections in the USA in 2016. Ocular anesthesia is required, both for patient safety and for tolerability ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. TOPIC 360: A SIMPLE END-TO-END SYSTEM FOR SERIAL CELL SORTING AND MANIPULATION USING A SINGLE CONTAINER

    SBC: DIAGNOLOGIX, LLC            Topic: NCI

    Chemotherapy may control but rarely cure metastatic cancers. Remarkably, modern immunotherapies, including cell-based therapies, have cured metastatic melanomas and other types of cancers. A major challenge for all cell therapies in general is the need to develop cost-effective and efficient manufacturing and delivery capabilities. We have recently established an innovative cell isolation technolo ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Prospective evaluation of a surgical solution for breast cancer-associated lymphedema

    SBC: Fibralign Corporation            Topic: 102

    Project Summary/Abstract Prospective evaluation of a surgical solution for breast cancer-associated lymphedema The proposed project will complete remaining key research and technology requirements that are needed to commercialize a ground-breaking interventional device for treating secondary lymphedema -- a chronic and debilitating disease that currently has no cure and impacts an estimated 15-30% ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Developing Species Specific Human Taeniasis Coproantigen Detection Immunoassays

    SBC: QOOLABS INC            Topic: ODCDC

    As the major cause of acquired epilepsy in developing countriesNeurocysticercosisNCCis the infection of the human nervous system by the larvae of the pork tapewormTaenia soliumReportable cases are seen in non endemic countries because of increasing travel and immigrationMany infected persons are unaware of their infection or the potential risks of transmission to othersIt is important to control a ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  5. Development of a Benchtop Laboratory Platform for Amplicon Deep Sequencing

    SBC: TRACE-ABILITY INC            Topic: ODCDC

    This proposal focuses on a solution that would address the above issues by enabling a compact and completely automated closed platform that allows DNA libraries preparation from clinical samples for deep sequencing on the MiSeq Illumina systemThe resulting benefits would be process efficiency and accessibility to NGS in parts of the world where proper laboratorieshighly skilled personnelor simply ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  6. MicroSkills Training and Harm Reduction Kits to Support Non prescription Syringe Distribution by Pharmacies

    SBC: DFUSION INC.            Topic: ODCDC

    The long term goal of this project is to improve public health through the reduction of the spread of HIVHepatitis C virusand other health concerns among persons who use injection drugsPWIDPWID who share needlessyringesand other drug preparation equipment face an increased risk for bloodborne infectionsincluding HIVHepatitis C virusHCVand Hepatitis B virusHBVAn effective means for reducing the tra ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  7. Dried bead format one step RT PCR assay for rabies screening

    SBC: CROSSLIFE TECHNOLOGIES INC.            Topic: ODCDC

    We propose in this proposal to complete the developmentvalidation and pursuing appropriate regulatory approvals or waivers for a RABV One Step RT PCR test kit commercializationThis rabies testing kit is planned to be developed as a user friendlyrapidand specific assay with the targeting sample types including salivaeyewashesand skin biopsiesThe kits are intended to be used for rabies transmission ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  8. Identification of Brucella canis seroreactive antigens using a pan Brucella proteome microarray

    SBC: ImmPORT Therapeutics Inc dba Antigen Discovery Inc            Topic: ODCDC

    Brucellosis is a worldwide re emerging bacterial zoonosis that can affect a range of different mammals including cattlesheepgoatsswinedogsand importantly humansEvery yearmore thanpeople worldwide are infected with virulent strains of Brucellagram negative coccobacillus from animal hostsEstimates have been made suggesting the true incidence may be much higherFour Brucella species that have animal h ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  9. Topic 377: Bridging the Guideline Implementation Gap: Clinical Decision Support to Improve Cancer Symptom Management

    SBC: Cognitive Medical Systems, Inc.            Topic: NCI

    Advances in clinical research have yielded many evidence-based guidelines to help clinicians provide the right care for the right patient at the right time; however, studies suggest that nearly half the time, that care does not reach the patient. Clinical decision support (CDS) is an information technology-enabled method to identify missed opportunities and optimize care. This proposal seeks to sy ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Topic 371: Validation and Optimization of RP-185 as Adjuvant to Exploit the Immune Response Generated by Radiation

    SBC: Riptide Bioscience, Inc.            Topic: NCI

    Radiotherapy, a key anticancer therapy, acts not only by killing cancer cells, but also by activating the body's immune system to attack the remaining cancer cells. However, the immune-stimulating effect is weakened by the tumor's capacity to reprogram immune cells, particularly macrophages, so that they instead actively promote tumor growth. RP-185 (Riptide Biosciences, Vallejo, CA),an engineered ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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