Award Data

"Given the exigency to rein in our nation’s energy consumption and carbon emissions, a nationwide deployment of Geothermal Heat Pumps (GHPs) would help mitigate our demands on the earth’s resources by reducing energy requirements for heating and cooling. Geothermal Heat Pump systems are a proven renewable energy resource that provides significant energy savings as compared to typical heating ...

"Since March 2006, Boulder, Colorado based Cool Energy, Inc. (CEI) has prototyped three generations of a novel low-temperature Stirling engine to generate electricity for low-to-medium temperature (100°C to 250°C) heat sources including solar thermal, geothermal and waste heat. With a marketing name for the SolarHeart® Engine, in its most recent operation in April, 2010, over 1800 watts of out ...

"The large-scale production of nanoparticles of the highest purity will be accomplished by the Eltron Solvent-free Powder Synthesis (ESPS) system described in this proposal. Since conventional particle size reduction methods are unable to reduce particles to the nano-scale and tend to reduce the purity of the powders, the ESPS system has been designed for direct yield of high purity and nano-size ...

"The oil refining industry is one of the most significant sources of greenhouse gas emissions, with considerable contribution from downstream activities. CO2 emissions from refineries rank third among the stationary producers (after power and cement industries), accounting for about 4% of the global CO2 emissions, approaching 1 billion tons per year. In addition, the oil refineries also emit sig ...

DESCRIPTION (provided by applicant): Malignancies of the brain are among the most devastating diseases known. Glioblastoma multiform (GBM) in particular are known for their rapid, uncontrolled, and aggressive growth. Very little progress has been made in the treatment of GBM over the past 25 years. A more recent promising therapeutic approach is convection enhanced delivery (CED) in which chemothe ...

DESCRIPTION (provided by applicant): Where arm functioning has been compromised due to a stroke, brain injury, or other neurological injury and rehabilitative progress is to be obtained in the upper extremity, it is crucial to limit over-stretching of theshoulder joint (attributed to lost muscle tone) and to control pain. Medeon, LLC is actively working with rehabilitation experts to develop the ...

DESCRIPTION (provided by applicant): Among amputation types involving the upper limbs, partial hand is the most prevalent by far and among the most challenging for prosthetists to address well. Sound side overreliance for these amputees gives rise to a high prevalence of contralateral overuse syndrome (COS), a progressive, painful, and debilitating condition. Research shows that prostheses reduce ...

DESCRIPTION (provided by applicant): Introduction of small interfering RNAs (siRNAs) into cells with transfection reagents results in efficient gene silencing. Unfortunately, while siRNA-based functional genomics is widely used in vitro, the ability to apply this technology to primary cells and in vivo target validation has been impeded limited availability of efficient and non-toxic delivery syst ...

DESCRIPTION (provided by applicant): In this Phase I SBIR project, TDA Research, Inc. will develop a compact, lightweight portable oxygen concentrator (POC) for medical operations and carry out a breadboard demonstration to produce continuous flow of enriched oxygen (O2) from ambient air. The new POC will weigh less than 10 lbs including the rechargeable batteries that will provide a minimum of 10 ...

DESCRIPTION (provided by applicant): It is a rare event when new and useful medical parameters can be added to the suite of monitoring and diagnostic tests available in a clinical setting. Of particular importance is the ability to measure crucial physiological parameters or analytes in a continuous and noninvasive manner-evidenced by the importance of noninvasive vital signs monitoring-because it ...