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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Identification of Patients with Clostridium Difficile Infection, Colonization and/or Reoccurrence

    SBC: AGAVE BIOSYSTEMS INC.            Topic: N/A

    Clostridium difficile infection (CDI) results in excess of 14,000 deaths and over $1 billion in excess healthcare costs annually. Early and reliable diagnosis is key for both improving treatment outcomes, and instituting precautions to prevent transmission. Antibiotic therapy can actually increase the odds of coming down with a hospital-acquired infection, especially when the cause is a bacterium ...

    SBIR Phase I 2014 Department of Health and Human Services
  2. Advanced Micro-patterned Wound Dressings for Enhanced Epithelialization

    SBC: Sharklet Technologies Inc.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Nearly 12 million wounds are treated in U.S. emergency departments every year. Skin wounds such as severe burns, large trauma wounds, or non-healing/chronic wounds that are too extensive or complex to close by natural healing are often reconstructed using autologous skin grafts. Although autologous skin grafts are currently the gold standard in complex wound re ...

    SBIR Phase I 2014 Department of Health and Human Services
  3. Novel Polymer Matrix for Dental Applications

    SBC: TDA Research, Inc.            Topic: NIDCR

    DESCRIPTION (provided by applicant): Dental caries are the most common childhood disease in the United States. Dental sealants are materials that are applied to the pits and fissures of healthy teeth to prevent dental caries or other forms of decay. This method prevents bacteria ingress and acid dissolution and targets the portions of the tooth surface where ~90% of the decay develops. Peer-review ...

    SBIR Phase I 2014 Department of Health and Human Services
  4. Smad7 use in oral mucositis treatment

    SBC: TAIGA BIOTECHNOLOGIES INC            Topic: NIDCR

    DESCRIPTION (provided by applicant): Summary Oral mucositis, a severe oral ulceration, is a common toxic effect of radio- or chemoradio-therapy and a limiting factor to using the maximum dose of radiation for effective cancer treatment. About 17.9 millionadults have been diagnosed with cancer in the United States, which is ~7.9% of the total population. At least 40%, and up to 70%, of individuals ...

    SBIR Phase I 2014 Department of Health and Human Services
  5. Novel Methacrylate-Thiol-Ene Composites for Dental Restorative Materials

    SBC: COLORADO PHOTOPOLYMER SOLUTIONS, LLC            Topic: NIDCR

    DESCRIPTION (provided by applicant): Novel Methacrylate-Thiol-Ene Composites for Dental Restorative Materials. As the demand for aesthetically pleasing restorative materials has increased, so has the desire and demand for improved performance. Despite their increasing prevalence, the resin phase of these materials has remained largely unaltered since Bowen first proposed the materials nearly 50 ye ...

    SBIR Phase I 2014 Department of Health and Human Services
  6. Transitional Care Program for Medicaid Patients and Integrated Care Teams

    SBC: PHCC LP            Topic: NIDDK

    DESCRIPTION (provided by applicant): Preventable hospital admissions and readmissions are indicators of health system fragmentation and are associated with suboptimal patient outcomes and avoidable costs of care. Readmissions often result from leaving discharged patients to their own devices, unable to follow instructions they didn't understand, and not taking medications or getting the nece ...

    SBIR Phase I 2014 Department of Health and Human Services
  7. Flow sensing for an artificial pancreas

    SBC: FLUONIC, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The long term objective of diabetes treatment is to create an artificial pancreas to substitute for the role of the biological pancreas in patients. This artificial pancreas must constantly measure glucose and respondwith an appropriate dose of insulin and/or glucagon to achieve an artificial analog to homeostasis. However, the artificial pancreas is subject ...

    SBIR Phase I 2014 Department of Health and Human Services
  8. Personal Exposure Monitoring of the Air Pollutants Ozone and Black Carbon as a K-

    SBC: 2B TECHNOLOGIES, INC.            Topic: NIEHS

    DESCRIPTION (provided by applicant): We propose to make air pollution personal by enabling K-12 students to act as citizen scientists using sophisticated, mobile air pollution monitors to measure their individual exposures to black carbon, a primary pollutant, and ozone, a secondary pollutant. Through their experiments and specially designed curricula, students will learn when and where they and o ...

    SBIR Phase I 2014 Department of Health and Human Services
  9. Electrochemical Paper-Based Analytical Devices for Metal Determination

    SBC: Access Sensor Technologies LLC            Topic: NIEHS

    DESCRIPTION (provided by applicant): The goal of this project is to develop a new electrochemical paper-based analytical device (ePAD) for measurement of Cu, Fe, Ni, Co, and Mn in airborne particulate matter (PM). PM represents one of the most significantenvironmental health threats to people in both developed and developing countries as a result of exposure in indoor, outdoor, and occupational se ...

    SBIR Phase I 2014 Department of Health and Human Services
  10. Perchlorate Sensing Platform for In-Field Groundwater Monitoring

    SBC: TDA Research, Inc.            Topic: NIEHS

    DESCRIPTION (provided by applicant): New and improved technologies are needed for monitoring perchlorate contamination in groundwater. TDA Research Inc. proposes a new portable sensor platform for in-the-field monitoring of the perchlorate anion, ClO4-, for which the recommended remediation goal is less than 3.6 parts-per-billion (3.6 ppb) in water. Perchlorate is a toxic anion that interferes wi ...

    SBIR Phase I 2014 Department of Health and Human Services

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