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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Identification of Patients with Clostridium Difficile Infection, Colonization and/or Reoccurrence

    SBC: AGAVE BIOSYSTEMS INC.            Topic: N/A

    Clostridium difficile infection (CDI) results in excess of 14,000 deaths and over $1 billion in excess healthcare costs annually. Early and reliable diagnosis is key for both improving treatment outcomes, and instituting precautions to prevent transmission. Antibiotic therapy can actually increase the odds of coming down with a hospital-acquired infection, especially when the cause is a bacterium ...

    SBIR Phase I 2014 Department of Health and Human ServicesCenters for Disease Control and Prevention
  2. Gamma-ketoaldehyde scavengers for alcoholic liver disease

    SBC: MTI Biotech Incorporated            Topic: NIAAA

    DESCRIPTION (provided by applicant): Chronic alcohol overconsumption is the third largest risk factor for disease burden worldwide and is a frequent comorbidity of liver disease and cancer. While abstinence is a cornerstone of treatment, there is considerable interest in identifying other therapeutic interventions for alcoholic liver disease (ALD). Such advances are complicated by an incomplete un ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Advanced Micro-patterned Wound Dressings for Enhanced Epithelialization

    SBC: Sharklet Technologies Inc.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Nearly 12 million wounds are treated in U.S. emergency departments every year. Skin wounds such as severe burns, large trauma wounds, or non-healing/chronic wounds that are too extensive or complex to close by natural healing are often reconstructed using autologous skin grafts. Although autologous skin grafts are currently the gold standard in complex wound re ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Quantitative Test of the Success/Reduction of Harm of Smoking Cessation Treatment

    SBC: BEHAVIORAL DIAGNOSTICS, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): Cigarette smoking is the most common preventable cause of morbidity and mortality in the United States. Over the past 20 years, several effective treatments, including varenicline, bupropion and nicotine replacement treatments (NRT, such as nicotine gum or patches) have been developed. Despite significant efforts, the overall success of these treatments for sm ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Polymer Matrix for Dental Applications

    SBC: TDA RESEARCH, INC.            Topic: NIDCR

    DESCRIPTION (provided by applicant): Dental caries are the most common childhood disease in the United States. Dental sealants are materials that are applied to the pits and fissures of healthy teeth to prevent dental caries or other forms of decay. This method prevents bacteria ingress and acid dissolution and targets the portions of the tooth surface where ~90% of the decay develops. Peer-review ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Smad7 use in oral mucositis treatment

    SBC: Taiga Biotechnologies, Inc.            Topic: NIDCR

    DESCRIPTION (provided by applicant): Summary Oral mucositis, a severe oral ulceration, is a common toxic effect of radio- or chemoradio-therapy and a limiting factor to using the maximum dose of radiation for effective cancer treatment. About 17.9 millionadults have been diagnosed with cancer in the United States, which is ~7.9% of the total population. At least 40%, and up to 70%, of individuals ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Novel Methacrylate-Thiol-Ene Composites for Dental Restorative Materials

    SBC: COLORADO PHOTOPOLYMER SOLUTIONS, LLC            Topic: NIDCR

    DESCRIPTION (provided by applicant): Novel Methacrylate-Thiol-Ene Composites for Dental Restorative Materials. As the demand for aesthetically pleasing restorative materials has increased, so has the desire and demand for improved performance. Despite their increasing prevalence, the resin phase of these materials has remained largely unaltered since Bowen first proposed the materials nearly 50 ye ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Development of a Porcine Model of Autosomal Dominant Polycystic Kidney Disease

    SBC: EXEMPLAR GENETICS, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common, potentially fatal genetic disorders in humans with an incidence of 1 in every 500-1000 individuals. The majority of ADPKD cases (85%) are caused by mutations in the PKD1 gene, which encodes polycystin-1. ADPKD is a systemic disorder that often leads to kidney failure and extrarenal ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Transitional Care Program for Medicaid Patients and Integrated Care Teams

    SBC: PHCC LP            Topic: NIDDK

    DESCRIPTION (provided by applicant): Preventable hospital admissions and readmissions are indicators of health system fragmentation and are associated with suboptimal patient outcomes and avoidable costs of care. Readmissions often result from leaving discharged patients to their own devices, unable to follow instructions they didn't understand, and not taking medications or getting the nece ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Flow sensing for an artificial pancreas

    SBC: FLUONIC, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The long term objective of diabetes treatment is to create an artificial pancreas to substitute for the role of the biological pancreas in patients. This artificial pancreas must constantly measure glucose and respondwith an appropriate dose of insulin and/or glucagon to achieve an artificial analog to homeostasis. However, the artificial pancreas is subject ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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