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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Novel Bone-Targeting Combination Therapy for Osteosarcoma

    SBC: MBC Pharma, Inc.            Topic: 102

    DESCRIPTION provided by applicant The overall aim of this project is to evaluate the feasibility of using a novel gemcitabine ibandronate conjugate alone and or as part of a combination therapy for the treatment of osteosarcoma and associated metastases The conjugate consists of chemically linked anticancer antimetabolite Gemcitabine and the bone homing bisphosphonate Ibandronate The novel co ...

    SBIR Phase I 2016 Department of Health and Human Services
  2. Micropatterned surfaces for minimizing percutaneous gastrostomy tube complications

    SBC: Sharklet Technologies Inc.            Topic: NICHD

    DESCRIPTION provided by applicant Enteral nutrition using feeding tubes provides a long term means of improving the nutritional status for infants and children with neurological syndromes cancer gastrointestinal disease cardiac disease and metabolic disease by allowing administration of feeding formula directly to the stomach through the upper abdomen More than pediatric percutaneo ...

    SBIR Phase I 2016 Department of Health and Human Services
  3. PINPOINT: Gaming technology to engage adolescent sickle cell patients in precision pain management

    SBC: KLEIN BUENDEL, INC            Topic: 102

    DESCRIPTION provided by applicant Sickle cell disease SCD is the most common inherited blood disorder in the U S and disproportionately affects African Americans and Hispanics Approximately U S children are born with SCD annually SCD results from abnormal hemoglobin and causes red blood cells RBCs to become misshaped andquot sickle shapedandquot Sickled cells can block the fl ...

    SBIR Phase I 2016 Department of Health and Human Services
  4. Pulse Oximeter Innovation to Measure Pulsus Paradoxus and Respiratory Disease Severity

    SBC: Kestrel Labs Inc            Topic: NHLBI

    DESCRIPTION provided by applicant Asthma is the most common chronic childhood disease and the most frequent reason for hospitalization of children It is also the most common chronic respiratory disorder in adults It results in over million emergency department visits and about hospitalizations annually in the U S alone The National Institutes of Health NIH expert guidelines re ...

    SBIR Phase I 2016 Department of Health and Human Services
  5. Innovative Optical System for Hemagglutination Assays

    SBC: INDEVR, INC.            Topic: NIAID

    PROJECT SUMMARY The Hemagglutination assay HA and Hemagglutination Inhibition HI assay are widely used methods for characterizing viruses bacteria and antibodies The World Health Organization recently recommended that HI remain the gold standard method for influenza seroepidemiology Although the HA and HI assays are applied worldwide they have the disadvantages of manual plate reading no ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Intervening to Prevent Youth Access to Marijuana Phase II

    SBC: KLEIN BUENDEL, INC            Topic: NIDA

    DESCRIPTION provided by applicant The legalization of marijuana in Alaska Colorado Oregon and Washington is the most dramatic change in U S substance abuse policy since the end of Prohibition These states are implementing regulatory and enforcement systems for the retail sales of recreational marijuana to adults years or older akin to state controls on the sale of alcohol In the ...

    SBIR Phase II 2016 Department of Health and Human Services
  7. High Resolution Magnetoencephalography using Atomic Magnetrodes

    SBC: QUSPIN INC.            Topic: 101

    DESCRIPTION provided by applicant We propose to develop a small fully integrated ultra sensitive commercial magnetometer that will merge the multi use and cost effective attributes of present EEG electrodes with the sensitivity of SQUID sensors Our device referred to as a magnetrode will combine reliable autonomous operation with straightforward multi channel integration for a robust MEG ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Development of Optimized Endectocide-treated Bird Feed Formulations for West Nile Virus Control

    SBC: TDA Research, Inc.            Topic: NIAID

    Project Summary Abstract Development of Optimized Endectocide treated Bird Feed Formulations for West Nile Virus Control STTR Phase I Application PIs Brady Clapsaddle TDA Research Inc Dr Brian Foy Colorado State University West Nile Virus WNV is the leading cause of domestically acquired arboviral disease in the United States resulting in significant disease and death every year in both ...

    STTR Phase I 2016 Department of Health and Human Services
  9. Wide field of view 3D microscopy for calcium imaging and photostimulation

    SBC: MEADOWLARK OPTICS, INC.            Topic: 101

    Project Summary Abstract Mental disease including schizophrenia depression and autism spectrum disorders are still poorly understood although it is clear that they mostly represent cortical disorders The cortex is the primary site of higher mental functions and despite extensive research there is still no unified theory of how the cortex works This is partly due to the fact that neuroscie ...

    SBIR Phase I 2016 Department of Health and Human Services
  10. "A Tool to Improve Evaluation of Patient Navigation Services in Under-served Populations"

    SBC: NATIVE AMERICAN CANCER INITIATIVES, INC.            Topic: NIMHD

    Native American Cancer Initiatives Inc NACI is a woman owned minority American Indian business with fewer than three full time equivalent employees This for profit company founded in has the mission to provide technical assistance and products to communities patients researchers academicians universities research institutions and professionals on Native Americans cultural iss ...

    SBIR Phase I 2016 Department of Health and Human Services

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