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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Topic 364: SysMet: Integrative Systems Metabolomics

    SBC: OMICSCRAFT LLC            Topic: NCI

    Metabolomics plays an indispensable role in the growing systems biology approaches to identify reliable cancer biomarkers. Liquid chromatography coupled to mass spectrometry (LC-MS) and gas chromatography coupled to mass spectrometry (GC-MS) have been extensively used for high-throughput comparison of the levels of thousands of metabolites among biological samples. However, the potential values of ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. TOPIC 356: FLOUROGENIC ASSAY PLATFORM FOR CIRCULAR RNA DETECTION

    SBC: LUCERNA INC            Topic: NCI

    Circular RNAs (circRNAs) are a novel class of non-coding RNAs that are an abundant component of the epitranscriptome. Putative functions of circRNAs, include miRNA sequestration, RNA-binding protein scaffolding, mRNA trapping, and protein translation regulation. Deregulation in one or more of these roles has been linked to several types of cancer, including pancreatic cancer, basal cell carcinoma, ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. New and Innovative Overhead Persistent InfraRed (OPIR) Sensor Tasking Capabilities

    SBC: BLACK RIVER SYSTEMS COMPANY, INC.            Topic: MDA13007

    Our objective is to develop and demonstrate an integrated capability to perform dynamic retasking of enterprise wide management of OPIR, radar, and other operationally relevant sensors. The goals of this effort are to refine our existing OPIR tasking approach and to develop and Enterprise SRM approach that will allow the C2BMC to achieve the earliest possible launch detection and maintain the high ...

    SBIR Phase II 2018 Department of DefenseMissile Defense Agency
  4. Configurable Link Test Set (CoLTS) Jamming Capability

    SBC: WELKIN SCIENCES, LLC            Topic: MDA10003

    Under this Phase II SBIR effort Welkin Sciences will design and implement a Jammer Emulator hosted on the MDA sponsored CoLTS-LC hardware platform, originally built for nuclear-effects channel simulation.The Jammer Emulator will support emulation of a wide range of jamming methods, including frequency-following, which is not readily implemented using standard commercial test equipment.A remote int ...

    SBIR Phase II 2018 Department of DefenseMissile Defense Agency
  5. LG Technology Innovative Research, Streamlining Scenario Generation Across a System of Systems Simulation Enterprise

    SBC: STILMAN ADVANCED STRATEGIES, LLC            Topic: MDA16006

    To enhance Operational Test (OT) fidelity, increase automation, and shorten the testing process, the Missile Defense Agency (MDA) seeks innovative research efforts to develop scenario generation technologies. STILMAN proposes to conduct novel research to develop a highly automated and ‘composable’ scenario generation toolset. Currently, in the distributed system of systems Operational Test ...

    SBIR Phase II 2018 Department of DefenseMissile Defense Agency
  6. Advanced Rocket Trajectory Propagation Techniques

    SBC: Reservoir Labs, Inc.            Topic: MDA17T002

    Reservoir Labs and Johns Hopkins University will develop alternative numerical solution techniques that improve computational loading, data storage, and data integrity for rocket vehicle trajectory modeling in MDA federated simulations.The objective of this program is to develop new techniques for trajectory propagation that are more suited for use in federated simulations than traditional methods ...

    STTR Phase I 2018 Department of DefenseMissile Defense Agency
  7. Topic 374: Topical Delivery of Nanoformulated Bioactive Chemopreventive Agent in Skin Cancer

    SBC: VASCULAR VISION PHARMACEUTICAL CO            Topic: NCI

    We plan to evaluate the chemopreventive management of solar ultraviolet (UV) mediated DNA damage by two different Nanoformulation of epigallicatechin-3-gallate (EGCG). The formulations to be assessed under this study include: a) chitosan based formulation of EGCG (nano-EGCG), and b) EGCG containing chitosan based solid lipid nanoparticles (E-Ch-SLNPs). EGCG is well-tested and popular polyphenol in ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Topic 377: Enabling Clinical Decision Support for Guideline Based Cancer Symptom Management

    SBC: KLESIS, LLC            Topic: NCI

    The objective of this proposal is to develop an electronic, rule-based clinical decision support system (CDS-Sx) that leverages national clinical practice guidelines (CPGs) to improve cancer symptom management. Specific tasks that will be performed include: 1) create software-ready computable algorithms for managing cancer-related fatigue and constipation that have been vetted with diverse cancer ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Topic 341: Open Scalable Software Infrastructure for Metabolomics Data

    SBC: KITWARE INC            Topic: NCI

    Metabolomics research has great potential, and researchers are rapidly producing new techniques for analyzing the large quantities of measurement data in order to utilize metabolomic data more effectively, including promising techniques for data integration across multiple modalities of data from mass spectrometry (MS) and nuclear magnetic resonance (NMR). However, this confluence of data growth a ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Topic 374: Targeted and Sustained Release Microparticles for Colon Cancer Chemoprevention

    SBC: ZYMERON CORP            Topic: NCI

    Colorectal Cancer (CRC) is the third most common cancer both in men and women, as well as the second leading cause of cancer deaths with an estimated 135,430 new cases diagnosed and 50,260 deaths for 2017 in the United States. Given the limitations of screening tests and poor prognosis associated with advanced stage colorectal cancer, it would be of great interest in exploring chemoprevention stra ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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