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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Producibility of Gallium Nitride Semiconductor Materials

    SBC: KYMA TECHNOLOGIES, INC.            Topic: MDA09T001

    The overall objective of this program is to improve the producibility of HVPE GaN through the use of in-situ monitoring during the growth process. Various in-situ monitoring devices will be used: a UV absorption technique to monitor the GaCl concentration above the growing GaN wafer; a commercial BandiT system capable of measuring optical emission from the growing wafer in order to measure the su ...

    STTR Phase II 2012 Department of DefenseMissile Defense Agency
  2. Picture Me Alcohol Free: Engaging Youth in Community-Based Prevention

    SBC: PREVENTION STRATEGIES, LLC            Topic: NIAAA

    DESCRIPTION (provided by applicant): This application proposes to build on the successful Phase I Picture Me Alcohol Free (PMAF) feasibility pilot study. PMAF is a community-based program designed to train groups of youth to a) represent contributing factors and consequences (e.g., social availability, alcohol-involved crashes) of underage drinking in their communities through a specific photograp ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  3. A Novel Therapeutic for Liver Fibrosis

    SBC: Angion Biomedica Corp.            Topic: NIAAA

    DESCRIPTION (provided by applicant): Alcoholic and non-alcoholic liver fibrosis remains an unsolved challenge for the hepatologist as it can lead to cirrhosis and end-stage liver disease, a life-threatening condition that necessitates liver transplantation. Current therapeutic strategies for the treatment of liver fibrosis include changes in diet, life-style and/or medications to allevate the unde ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  4. Low Cost Laser Diagnostic for CD4+ T Cell Counting

    SBC: MBIO DIAGNOSTICS INC            Topic: NIAID

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop and commercialize a simple cell counter for routine enumeration of CD4 cells for management of HIV-infected individuals. HIV-1 mediated CD4 cell destruction is the centralimmunologic feature of HIV-1 infection. Thus, the CD4 count is a critical measurement in initial disease staging, in monitoring antiretroviral t ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  5. A new, rapidly dissolving and thermally stable dry powder Hepatitis-B vaccine

    SBC: AKTIV-DRY            Topic: NIAID

    DESCRIPTION (provided by applicant): The overarching goal of this project is to move a new, dry powder formulation of Hepatitis-B vaccine on its path to commercialization. In the Phase I SBIR we tested in vitro three Hep-B dry powder formulations of commercially available Shanvac-B and demonstrated powder stability and immunogenicity at temperatures ranging from -20 ?C through 65 oC. At these temp ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Novel PolC Inhibitor as a Gram-Positive Antibiotic

    SBC: CRESTONE, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): The alarming increase in incidence of infections caused by drug-resistant bacteria has created an urgent need for new antibacterial agents. We are developing a novel class of small molecule antibiotics ( TZUs ) targeting PolC, the replicative DNA polymerase in Gram-positive bacteria. These agents exhibit broad-spectrum activity against Gram-positive bacteria, ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  7. Robust, defined, animal-free cell culture medium for the production of vaccines

    SBC: VENTRIA BIOSCIENCE            Topic: NIAID

    DESCRIPTION (provided by applicant): The Vero cell line is used in the production of viral based vaccines. The use of cell based vaccines based on the Vero cell line is growing. The majority of the vaccines in use today are produced using cell culture medium supplemented with serum. The use of animal-derived products in vaccine culture media presents a risk for the transmission of infectious disea ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  8. Anti-Fibrotic Therapy for Scleroderma/SSc

    SBC: Angion Biomedica Corp.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Scleroderma (also known as systemic sclerosis-SSc) is characterized primarily by progressive dermal and vascular fibrosis. Other organs are affected too, including lung, heart, blood vessels, GI and kidney. Many patients who suffer from scleroderma/SSc also have a loss of pulmonary function. Scleroderma/SSc affects approximately 400,000 to 900,000 people in th ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Connective Tissue Motion Measure 2

    SBC: STROMATEC, INC            Topic: NCCAM

    DESCRIPTION (provided by applicant): Connective tissue dysfunction is emerging as a potentially important, and so far mostly overlooked, factor in the pathophysiology of chronic low back pain (LBP). We have developed and tested a novel instrument (StromaGlide) and test (Connective Tissue Motion Measure - CTMM) -quantifying the functional behavior of perimuscular connective tissues. The results of ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  10. A Needle Guidance System for Hepatic Tumor Ablation That Fuses Real-Time Ultrasou

    SBC: INNEROPTIC TECHNOLOGY INC            Topic: NCI

    DESCRIPTION (provided by applicant): We propose to develop an operating-room-ready system for needle guidance in soft tissue, which fuses intra- operative ultrasound and pre-operative X-ray computed tomography (CT) data by combining two novel technologies:1) a radically different way of visualizing and interacting with the fused ultrasound and CT images, which we call Spotlight ; and 2) an innova ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
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