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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Automated Vestibular Rehabilitation Management System

    SBC: CREARE LLC            Topic: DHA182005

    Dizziness is a common complaint, with about one third of the population experiencing dizziness at some point in their life. Vestibular rehabilitation targets vestibular adaptation and substitution for patients with vertigo and dizziness of vestibular origin. Unfortunately, vestibular rehabilitation requires specialized physical therapists who may not be accessible to service members or the general ...

    SBIR Phase I 2019 Department of DefenseDefense Health Program
  2. Development of an Automated Vascular Access Device

    SBC: CREARE LLC            Topic: DHA173003

    Vascular access is a critical and early step in the stabilization and treatment of critically injured soldiers and civilians. Traditional peripheral intravenous (PIV) access and central venous cannulation (CVC) access becomes exceedingly difficult in the field, particularly in patients who are volume-depleted from blood loss or dehydration, vasoconstricted, or hypothermic. We propose a self-contai ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  3. Development of a Wearable Bladder Monitoring System

    SBC: CREARE LLC            Topic: DHA172012

    Soldiers with spinal cord injury (SCI) face a lifetime of bladder dysfunction. Although the type and character of this dysfunction depends on the severity and level of spinal injury, many of these soldiers and veterans suffer from renal insufficiency, frequent and severe antibiotic-resistant bladder infections, and the emotional and social stress of unexpected bladder leakage. We propose that sign ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  4. MARS Phase II

    SBC: ATC-NY, Inc.            Topic: DHA172004

    System maintenance is time consuming, expensive, and can cause extensive downtime if done improperly. To avoid improper system maintenance, extensive training is often required for existing systems, with additional training required for new capabilities before they can be deployed. This training often slows the deployment of new capabilities. Based on a successful SBIR Phase I prototype, the ATC-N ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  5. Lightweight, Compact System for Generating Lactated Ringer's Solution

    SBC: TDA Research, Inc.            Topic: DHA172011

    Currently, deployed medics are required to transport, maintain and be resupplied with liquid-based medications and materials that are heavy, expensive to transport, perishable and may require refrigeration.Many medications and materials are or will soon be available in concentrated or dehydrated formularies that require sterile water for injection (SWFI) to rehydrate for immediate use, one of the ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  6. Chronological Sweat Sensor Patch for Real-Time Human Molecular Biomarker Monitoring

    SBC: TDA Research, Inc.            Topic: DHA18003

    Sweat contains biomarkers that give an indication of human cognitive levels. In this SBIR project TDA Research is developing a modular sweat sensor patch that has the capability to not only carry out real-time monitoring of select biomarkers, but also to collect multiple precisely time stamped chronological samples (50-150 Ls each) for off-line analysis in laboratory assays.In Phase I, we demonstr ...

    SBIR Phase II 2019 Department of DefenseDefense Health Program
  7. TOPIC 356: FLOUROGENIC ASSAY PLATFORM FOR CIRCULAR RNA DETECTION

    SBC: Lucerna Inc.            Topic: NCI

    Circular RNAs (circRNAs) are a novel class of non-coding RNAs that are an abundant component of the epitranscriptome. Putative functions of circRNAs, include miRNA sequestration, RNA-binding protein scaffolding, mRNA trapping, and protein translation regulation. Deregulation in one or more of these roles has been linked to several types of cancer, including pancreatic cancer, basal cell carcinoma, ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Topic 374: Topical Delivery of Nanoformulated Bioactive Chemopreventive Agent in Skin Cancer

    SBC: VASCULAR VISION PHARMACEUTICAL CO            Topic: NCI

    We plan to evaluate the chemopreventive management of solar ultraviolet (UV) mediated DNA damage by two different Nanoformulation of epigallicatechin-3-gallate (EGCG). The formulations to be assessed under this study include: a) chitosan based formulation of EGCG (nano-EGCG), and b) EGCG containing chitosan based solid lipid nanoparticles (E-Ch-SLNPs). EGCG is well-tested and popular polyphenol in ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Topic 377: Enabling Clinical Decision Support for Guideline Based Cancer Symptom Management

    SBC: KLESIS, LLC            Topic: NCI

    The objective of this proposal is to develop an electronic, rule-based clinical decision support system (CDS-Sx) that leverages national clinical practice guidelines (CPGs) to improve cancer symptom management. Specific tasks that will be performed include: 1) create software-ready computable algorithms for managing cancer-related fatigue and constipation that have been vetted with diverse cancer ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Topic 341: Open Scalable Software Infrastructure for Metabolomics Data

    SBC: Kitware, Inc.            Topic: NCI

    Metabolomics research has great potential, and researchers are rapidly producing new techniques for analyzing the large quantities of measurement data in order to utilize metabolomic data more effectively, including promising techniques for data integration across multiple modalities of data from mass spectrometry (MS) and nuclear magnetic resonance (NMR). However, this confluence of data growth a ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health

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