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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Solid-fueled Micro Colloid Thruster

    SBC: TDA RESEARCH, INC.            Topic: T301

    Nanosatellites are receiving increased interest since they are proving reliable for surveillance, communication and other space missions. Also, the possibility of launching "constellations" of them offers unique capabilities for low-cost experimentation, sensing and communications in space. In comparison to larger spacecraft, their development time and costs have reduced and their launch costs a ...

    STTR Phase I 2012 National Aeronautics and Space Administration
  2. A Self-Regulating Freezable Heat Exchanger for Spacecraft

    SBC: TDA RESEARCH, INC.            Topic: T601

    A spacecraft thermal control system must keep the cabin (both air and its structure if manned) and electronic equipment within a narrow temperature range even though the environment may vary from very cold to warmer than room temperature. Since water is safe to use and an excellent coolant (other than its high freeze point and volumetric expansion during freeze), a water coolant loop often is use ...

    STTR Phase I 2012 National Aeronautics and Space Administration
  3. Real-Time Smart Tools for Processing Spectroscopy Data

    SBC: Signal Processing, Inc.            Topic: T501

    Since Mars rovers have limited life span, NASA wants to maximize the exploration activities during this period. Rock sample analysis is one of the main tasks of rover missions. Traditionally, rock selection is decided by human operators. Due to long communication delay, manual selection process is time-consuming. There is a strong need to develop an automatic software system to automate the proces ...

    STTR Phase II 2012 National Aeronautics and Space Administration
  4. Alternative Green Technology for Power Generation Using Waste-Heat Energy And Advanced Thermoelectric Materials

    SBC: BRIMROSE TECHNOLOGY CORP            Topic: T803

    NASA is interested in advancing green technology research for achieving sustainable and environmentally friendly energy sources. Thermo-electric power generation (TEPG) has exceptionally rich potential to fulfill this need. A TEPG module requires (1) material that can provide high figure of merit while still providing efficient heat control; (2) low resistance ohmic contacts that operate at high t ...

    STTR Phase II 2012 National Aeronautics and Space Administration
  5. Human Lactoferrin in Acetaminophen Overdose-Induced Liver Failure

    SBC: VENTRIA BIOSCIENCE            Topic: NIAAA

    DESCRIPTION (provided by applicant): An acute or cumulative overdose of acetaminophen (APAP), following either therapeutic overdose or suicide attempts, can cause severe liver damage with the potential to progress to liver failure. APAP overdose accounts for more than 56,000 emergency room visits, 2,600 hospitalizations, and an estimated 458 deaths due to acute liver failure each year, making APAP ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  6. Novel Biomarkers for Early Detection of Aspergillosis

    SBC: SOUTHEAST TECHINVENTURES INC            Topic: NIAID

    DESCRIPTION (provided by applicant): Invasive aspergillosis (IA) caused by the fungus Aspergillus fumigatus is the most frequent fungal cause of death in immunocompromised patients. The number of patients at risk for developing IA is steadily increasing due to advances in medicine. Early and accurate diagnosis of IA is critical to patient outcome, yet is exceedingly difficult due to the lack of sp ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  7. Treating EAE disease with Fc-Dimers

    SBC: LeukoSight Inc            Topic: NIAID

    DESCRIPTION (provided by applicant): We have developed a recombinant polypeptide that we have termed Fc-Dimers (Di -mers). This product has potent anti-inflammatory activity in vitro, and we propose to test this reagent in an animal model of autoimmunedisease. We have selected the murine disease, Experimental Autoimmune Encephalomyelitis (EAE), a model for human multiple sclerosis (MS). Pathol ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  8. Rational Design of Live Attenuated Influenza A Vaccine Candidates

    SBC: Codagenix Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Despite the availability of influenza vaccines, approximately 35,000 individuals die each year in the US alone from influenza, and influenza-related complications. The clinical impact of Influenza motivates the search for new, more effective vaccines that can be rapidly designed and easily produced. We have developed a rational, computer-aided approach to const ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Suv39H Targeted Therapy for Treatment of Childhood Rhabdomyosarcoma

    SBC: BUFFALO BIOLABS, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): Rhabdomyosarcoma (RMS) is a childhood malignant tumor and is thought to arise due to the arrest of skeletal muscle differentiation (myogenesis) program. It accounts for 3.5% of all malignancies in children. Despite multimodality therapeutic treatment approaches, the outlook for patients with metastatic subtype, alveolar rhabdomyosarcoma (ARMS), remains unchange ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  10. CMV Therapeutic Vaccine for the Treatment of Glioblastoma

    SBC: Annias Immunotherapeutics, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): Recently, temozolomide (TMZ), a myelosuppressive alkylating chemotherapy, has shown a benefit in patients with glioblastoma multiformes (GBM), but median survival is still less than 15 months. Moreover, these conventional chemotherapies lack specificity and result in incapacitating damage to surrounding normal brain and systemic tissues. Immunotherapy may provi ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
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