Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. MarsOasis- An Efficient Autonomously Controlled Martian Crop Production System

    SBC: Space Lab Technologies, LLC            Topic: T7

    The MarsOasistrade; cultivation system is a versatile, autonomous, environmentally controlled growth chamber for food provision on the Martian surface.nbsp; MarsOasistrade; integrates a wealth of prior research and Mars growth chamber concepts into a complete system design and operational prototype.nbsp; MarsOasistrade; includes several innovative features relative to the state of the art space gr ...

    STTR Phase II 2020 National Aeronautics and Space Administration
  2. Validated Engineering Tools for Thin-Ply Composites

    SBC: Opterus Research and Development, Inc.            Topic: T12

    Opterus Research and Development, Inc. proposes to develop and validate multi-scale thin-ply High Strain Composites (HSCs) constitutive modeling tools for incorporation into commercial finite element analysis codes. The constitutive models will capture the time-temperature-load-deformation viscoelastic characteristics common to HSCs as well as the yielding or permanent deformation associated with ...

    STTR Phase II 2020 National Aeronautics and Space Administration
  3. Sentient Science- A Multiscale Modeling Suite for Process and Microstructure Prediction in Metal Additive Manufacturing

    SBC: Sentient Science Corporation            Topic: T12

    In the Phase I period, Sentient upgraded its DigitalClone for Additive Manufacturing (AM) technology and successfully demonstrated and validated its ldquo;Process modelrdquo; and ldquo;Microstructure modelrdquo; for simulating metal AM processes. Sentient has partnered with University of Nebraska ndash; Lincoln for model validation.Specifically, Sentient has implemented a new ldquo;Process modelrd ...

    STTR Phase II 2020 National Aeronautics and Space Administration
  4. Integrated Mid-Infrared Sources Enabled by Waveguides Written with Femtosecond Lasers

    SBC: AKTIWAVE LLC            Topic: T8

    This proposal addresses, for the first time, the demonstration of integrated mid-infrared sources based on waveguiding in a bonded solid-state laser material and periodically poled nonlinear material. A focused femtosecond laser beam allows for precisely localized modification of the refractive index of a material, therefore enabling to create waveguiding structures. The offeror has demonstrated f ...

    STTR Phase II 2020 National Aeronautics and Space Administration
  5. A Robust Biofilm-Biomat Reactor for Conversion of Mission-Relevant Feedstocks to Products

    SBC: SUSTAINABLE BIOPRODUCTS LLC            Topic: T7

    Sustainable Bioproducts (SBP) has developed a simple and energy efficient bioreactor technology for the purpose of supporting NASArsquo;s in-situ microbial manufacturing needs. The technology capitalizes on the robust nature of filamentous fungi grown as biofilms. SBP has shown that the system can be used to convert a multitude of mission available feedstocks into dense, easily harvestable biomats ...

    STTR Phase II 2020 National Aeronautics and Space Administration
  6. Novel Small Molecule Macrophage Inhibitors for the Treatment of Retinal Diseases

    SBC: Eyedesis Biosciences, LLC            Topic: N

    PROJECT SUMMARY ABSTRACT Persistent disease activity PDA in spite of anti vascular endothelial growth factor VEGF therapy remains a significant clinical unmet need for patients with neovascular age related macular degeneration NVAMD The purpose of this STTR Phase I grant application is to develop novel therapies that will be effective for the treatment of PDA associated with NVAMD The cu ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Developing a small peptide to control autoimmune inflammation in type diabetes

    SBC: Op-T-Mune, Inc            Topic: NIAID

    Abstract Type Diabetes T D affects an ever growing population While this disease typically has been associated with juveniles the disease in adult populations is rapidly increasing The defining clinical component is insulin loss which occurs because of sustained inflammation in the islets At present there is no means to prevent or reverse insulin loss A major inflammatory pathway in T D ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. In Vivo Editing for Hemophilia Gene Therapy

    SBC: GENVEC, INC.            Topic: 100

    Project Summary The exceptional promise of gene therapy for hemophilia has been shown in recent studies that result in long term correction of factor IX deficiency via hepatic transduction with an adeno associated vector AAV In spite of this watershed event in the history of the gene therapy field there presently exist barriers to the fullest implementation of hemophilia gene therapy The li ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Personalized Neural Stem Cell Therapy for Cancer

    SBC: Falcon Therapeutics, Inc.            Topic: NCATS

    Project Summary Abstract Glioblastoma GBM is the most common primary brain tumor and one of the deadliest forms of cancer Standard surgery chemotherapy and radiation fail to eliminate the infiltrative invasive cancer cells Median survival remains only months Drugs that seek out the disseminated GBM cells behind the blood brain barrier will prevent the inevitable recurrence in patients ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Trans‐nasal delivery of chemotherapy to glioblastoma using magnetic nanoparticles and magnetic focusing

    SBC: Weinberg Medical Physics, Inc.            Topic: 102

    Abstract Glioblastoma multiforme GBM is the deadliest form of brain tumor The current treatment includes a combination of surgical resection chemotherapy radiation and electrical disruption of mitosis has only extended survival to approximately to years Preliminary pre clinical findings suggest the potential effectiveness of the candidate drug cyclopamine However the drug is toxic to ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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