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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. PREFAB MODULAR LIQUID-COOLED MICRO DATA CENTER

    SBC: Flexnode Inc            Topic: 1

    "To enable the future needs of efficient computing for edge data centers, Flexnode and its partners, the University of Maryland (UMD), Boeing, Iceotope, SHoP Architects, and Arup, propose to develop a prefabricated modular micro data center with unprecedented energy efficiency and power density. The proposed system leverages four key component and system-level technology advancements: (a) a novel, ...

    STTR Phase I 2024 Department of EnergyARPA-E
  2. PREFAB MODULAR LIQUID-COOLED MICRO DATA CENTER

    SBC: Flexnode Inc            Topic: 1

    "To enable the future needs of efficient computing for edge data centers, Flexnode and its partners, the University of Maryland (UMD), Boeing, Iceotope, SHoP Architects, and Arup, propose to develop a prefabricated modular micro data center with unprecedented energy efficiency and power density. The proposed system leverages four key component and system-level technology advancements: (a) a novel, ...

    STTR Phase II 2024 Department of EnergyARPA-E
  3. PREFAB MODULAR LIQUID-COOLED MICRO DATA CENTER

    SBC: Flexnode Inc            Topic: 1

    "To enable the future needs of efficient computing for edge data centers, Flexnode and its partners, the University of Maryland (UMD), Boeing, Iceotope, SHoP Architects, and Arup, propose to develop a prefabricated modular micro data center with unprecedented energy efficiency and power density. The proposed system leverages four key component and system-level technology advancements: (a) a novel, ...

    STTR Phase II 2024 Department of EnergyARPA-E
  4. Development of Novel Small Molecule Anti-Fibrotic Agent for the Treatment of Systemic Scleroderma

    SBC: APIE THERAPEUTICS INC            Topic: NHLBI

    ABSTRACT The goal of this STTR proposal is to develop a novel anti-fibrotic agent suitable for oral administration which could be used to safely and effectively treat Systemic Sclerosis (SSc), or Systemic Scleroderma patients. SSc is one of the most disabling and lethal immune-mediated rheumatic disorders. SSc is a rare disease, affecting 40,000-150,000 people in the United States and conferring a ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Targeted ColQ gene therapy for Congenital Myasthenic Syndromes

    SBC: Amplo Biotechnology, Inc.            Topic: 106

    PROJECT SUMMARY Congenital Myasthenic Syndromes (CMS) are a group of clinically similar neuromuscular transmission disorders that differ in their underlying genetic mutation. While some phenotypical variation exists, CMS are commonly characterized by muscle weakness (myasthenia) that worsens with physical exertion. Defects in Collagen Q (ColQ), a multidomain functional protein of the Neuro Muscula ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Inducible HMGB1 antagonist for viral-induced acute lung injury.

    SBC: SIGMOVIR BIOSYSTEMS, INC.            Topic: NHLBI

    For more than a decade, our work has focused on development of therapeutic interventions for viral- and bacterial-induced acute lung injury (ALI) and the more severe acute respiratory distress syndrome (ARDS). Significantly, we identified the Toll-like receptor 4 (TLR4) signaling pathway as key to the host response to influenza and secondary bacterial infection following influenza. We also identif ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a portable beat-to-beat fetal ECG system

    SBC: AUSCULTECH DX LLC            Topic: NICHD

    Project Summary There are 24,000 stillbirths per year in the United States, and 2.6 million stillbirths per year worldwide, with no significant decrease in the last decade. Abnormal fetal heart rhythms, such as long QT syndrome, are thought to play an important role in these deaths, and may cause 3- 10% of unexplained stillbirths. This is in addition to known fetal arrhythmias, which affect 1-3% o ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. A novel producer cell line for more efficient manufacturing of viral vector systems

    SBC: CLAIRIgene            Topic: 100

    ABSTRACT Significant advances in the specific targeting of delivery vectors and the increased therapeutic efficacy of such vectors for gene delivery have been made, stimulating major interest in the development and commercialization of therapeutic products focused on gene therapy indications. CLAIRIgene LLC focused on the development and optimization of various viral gene-to-cell transfer delivery ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Microfluidic technology platform as a continuous end-line process to inactivate pharmaceuticals

    SBC: NIGHTHAWK BIOSCIENCES, INC.            Topic: NCATS

    PROJECT SUMMARY To achieve the FDA’s required Sterility Assurance Level for use in humans, pharmaceutical products must undergo terminal sterilization or aseptic manufacturing. This can be accomplished using physical or chemical methods such as heat or formaldehyde for simple drug formulations; however, for pharmaceutical products that have more complex drug formulations or that contain biologic ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  10. A Therapeutic Role for Apolipoprotein-E in the Germ Theory of Alzheimer's Dementia

    SBC: REGENNOVA, INC.            Topic: R

    Abstract: A Therapeutic Role for Apolipoprotein-E in the Germ Theory of ADP. gingivalis is the keystone bacteria of periodontal disease, the 6th most common infectious disease worldwide. Half of all Americans over the age of 30 and 70% of those over age 65 suffer some degree of P. gingivalis infection associated with gum disease. In a study of 6800 patients with gum disease that were followed for ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
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