Award Data

Thegoal is to develop asoftwaretool that implementsa novelapproach applicableto fitgeneral pharmacologic, toxicology, or other biomedical data, that mayexhibita non-monotonic dose-responserelationship for which thecurrent parametricmodels fail. Thesoftwareexplores dose-responserelationships using both monotonicand non-monotonicmodels,and estimates theassociated doseresponsecurves,which can further ...

The DoD Medical Health Systems (MHS)seeksameans to collect, transport,and share patientcareinformation between disparateelectronicmedical record systems in austerelocations that lacksufficient or reliabletelecommunicationsconnectivity. Thesolution they seek must bereliablein deliveringlargeamounts of patient medical information, durablein demandingmilitaryenvironments,adaptableto current and evolv ...

Ensuring military field water supplies are safe for human consumption is of critical importance to the United States Armed Forces. However, despite the need to routinely monitor water supplies the availability of field-ready tests is limited. In 2019 the

Military personnel have endured over 1700 major limb amputations from the current conflicts alone. Since the military population is young and active, there is an increased demand for effective and expedient prosthetic devices. This requires an efficient p

Over 50,000 American warfighters had been wounded in action in Operations Iraqi and Enduring Freedom (OIF/OEF) with over 1,500 requiring major limb amputations. Warfighters and first responders must have proper tools for pain management during prolonged

Joint reduction is a key skill and is a core competency for orthopedic surgeons deploying as part of a trauma team. Current training options are limited to classroom instruction on uninjured persons due to lack of a suitable training simulator. The first

Techulon has developed a platform based on peptide-peptide nucleic acids (PPNAs) molecules that are effective as antimicrobial compounds against multi-drug reisistant pathogens. Techulons targeted approach uses informatic algorithms applied towards an organisms genome to identify targets that will disrupt essential biological functions. The proposed Phase I project will focus on developing a new g ...

The use of the Walter Reed National Military Medical Center (WRNMMC) can be difficult for patients and visitors to use due to the size and complexity of the facility. The current a kiosk concierge system cannot offer turn-by-turn facility navigation. This proposal seeks to design a combined indoor/outdoor navigation service to aid using and locating services and people in the WRNMMC facility. ...

Traumatic injuries to the head and neck region comprise as much as 30 percent of all combat injuries observed today. These injuries often involve multiple tissues including dermal, muscle, cartilage and bone. This work aims to address this critical need by treating a composite tissue injury model in the ear. We will use an alginate microbead cell delivery system

Major organ injuries such as liver, kidney, heart and lung injuries can lead to high morbidity and mortality in critically ill patients. Advanced noninvasive testing with high sensitivity and specificity is needed to detect specific organ injury particularly at early stages. Current techniques such as PCR, MS, absorption-based assays, ELISA and microfluidic-Luminex, cannot meet such requirements. ...