Award Data

In the Phase I period, Sentient upgraded its DigitalClone for Additive Manufacturing (AM) technology and successfully demonstrated and validated its ldquo;Process modelrdquo; and ldquo;Microstructure modelrdquo; for simulating metal AM processes. Sentient has partnered with University of Nebraska ndash; Lincoln for model validation.Specifically, Sentient has implemented a new ldquo;Process modelrd ...

This proposal addresses, for the first time, the demonstration of integrated mid-infrared sources based on waveguiding in a bonded solid-state laser material and periodically poled nonlinear material. A focused femtosecond laser beam allows for precisely localized modification of the refractive index of a material, therefore enabling to create waveguiding structures. The offeror has demonstrated f ...

Orbit Logic and the Fraunhofer USA Center for Experimental Software Engineering propose development of a solution called SCRAMBL (Space Communication Reconstruction and Mapping with Blockchain Ledgering), which will leverage blockchain technology to store and distribute a ledger containing satellite constellation-relevant shared data to enable satellite onboard autonomy cooperative attendance of i ...

Vistexrsquo;s patented Pressure Focusing Layer (PFLtrade;) technology utilizes a computationally optimized mold set that provides the same uniform pressure and temperature as an autoclave. NASA calls for an innovative out-of-autoclave processing method for thin-gauge structures. Vistexrsquo;s PFL process directly addresses this need. Specifically, the PFL processrsquo; core strength is its ability ...

NASA is spearheading the efforts on Urban Air Mobility (UAM) and providing impetus to the industry to follow with concepts for the same. Several manufacturers, as well as, NASA, have come up with concepts for UAM aircraft; mostly using Distributed Electric Propulsion (DEP). However, the multidisciplinary interactions involved and the ability to utilize the distributed propulsors for improved contr ...

Orbit Logic is teamed with the University of Colorado at Boulder to develop Intelligent Navigation, Planning, and Autonomy for Swarm Systems (IN-PASS). The proposed technology builds on proven software ndash; to enable flexible composition of collaborative mission concepts assessed in an open simulation environment. The focus of IN-PASS is rover autonomous navigation ndash; specifically developmen ...

Abstract Prostate cancer (CaP) is the most common non-skin cancer in men and third most common cause of cancer deaths in men. Black men experience a higher burden of incidence and mortality from CaP compared to White men. The Prostate-Specific Antigen (PSA) test, a commonly used biomarker for early diagnosis and management of CaP, cannot alone accurately predict the presence of CaP, its aggressive ...

Research Summary: The KRAS proto-oncogene is one of the most critical genes in cancer, yet it has also proven to be among the most elusive. Nearly all (98%) of KRAS missense mutations occur in codons 12 or 13, which leads to constitutive KRAS activation and promotion of numerous cancer hallmarks. Although kinase inhibitors have revolutionized treatment of some subsets of cancers driven by other mo ...

Pulmonary arterial hypertension (PAH) affects ~15-50 individuals per million and claims ≥20,000 lives annually in the United States. It affects every ethnic group, race, age and gender, and devastates high-risk patients afflicted with HIV, systemic sclerosis, and sickle cell disease. The disease affects more women than men; adult PAH patients do not live more than five years after the diagnosis. ...

PROJECT SUMMARY According to the CDC, 550,000 Healthcare Associated Infections (HAIs) occur per year in the US, costing ~$100 billion and killing tens of thousands of patients. Reducing HAIs is a top priority of the US DHHS and NIH and experts have called for novel strategies including vaccination to achieve this goal.ExBaq was founded by scientists and business colleagues who have spent years stu ...