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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. A Novel Peptide-based Topical Therapeutic to Promote Corneal Regeneration and Restore Corneal Biomechanics Following Blast and Burn Injuries

    SBC: FirstString Research, Inc            Topic: A15061

    Ocular traumas resulting from explosive or incendiary devices are common battlefield injuries. Current therapeutics do not address the biological and molecular processes in corneal wound healing, and therapeutic failure is associated with corneal ulcers,

    SBIR Phase II 2017 Department of DefenseDefense Health Program
  2. Optimal Rewarming Solutions for Cryopreserved Tissue Systems: Rapid rewarming reduction of cryoprotectant toxicity and concentration employing magnetic nanoparticles.

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: DHP15014

    Vitrification, cryopreserved storage in a glassy rather than crystalline phase, is an important enabling approach for tissue banking and regenerative medicine, offering the ability to store and transport cells, tissues and organs for a variety of biomedical uses without the risks of damaging ice formation. Unfortunately, practical application of vitrification has been limited to reproductive cells ...

    SBIR Phase II 2016 Department of DefenseDefense Health Program
  3. Rapid Rewarming Reduction of Cryoprotectant Toxicity and Concentration Employing Magnetic Nanoparticles

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: DHP15014

    We will evaluate a novel warming method, developed by our collaborator John Bischof, that promises solution of one of the remaining barriers for banking of large organs and vascularized composite tissues. The method involves radiofrequency and magnetic nanoparticles to obtain rapid uniform electromagnetic rewarming of biological materials instead of warming from the outer boundary using convection ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program
  4. Avoiding the Ice Cryolesion in Tissue Cryopreservation with Ice Modulators

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: DHP15013

    The long term goal of the proposed research is to develop improved methods for cryopreservation of complex tissues at extreme low temperature. An innovative approach is taken in the proposed line of research, where synthetic ice modulators (SIMs) are combined with established cryoprotective agent (CPA) cocktails to create more favorable conditions for cryopreservation in a process known as vitrifi ...

    SBIR Phase I 2015 Department of DefenseDefense Health Program

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