You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A Double Balloon Catheter for the Treatment of Intussusception in Children

    SBC: Sealcath, LLC            Topic: NICHD

    PROJECT SUMMARY ABSTRACT During Phase ISealCathLLC will test the feasibility of its innovative Double Balloon CatheterDBCwhich the United States Utility Patent application was approved on Augustand is in the process of issuing a patentLicensed from the Medical University of South Carolinathis DBC will be commercialized in Phase III as the trademarked nameCephus Catheterwith targeted end users bein ...

    SBIR Phase I 2018 Department of Health and Human Services
  2. CranialProgrammer: Image-Guided Directional Deep Brain Stimulation Programming Using Local-Field Potentials

    SBC: Nexeon Medsystems Puerto Rico Operating Company Inc            Topic: 105

    ABSTRACT The goal of this Uproposal is to develop and test CranialProgrammeran image guided programming tool forDD mapping of disease related neural signals over patient and device data for more efficient and effective programming of directional deep brain stimulationDBSsystemsDBS is an established treatment for advancedrefractory movement disorders used in overpatientsHowevermany patients receive ...

    SBIR Phase I 2018 Department of Health and Human Services
  3. A Reliable Switched Angle Spinning (SAS) Probe with Gradients (PFG) for Proteins in Solid-State NMR

    SBC: DOTY SCIENTIFIC, INC.            Topic: 400

    A Reliable Switched Angle SpinningSASProbe with GradientsPFGfor Proteins in Solid State NMR AbstractSolid state NMRssNMRbiotechnology is emerging as an alternative method of choice for highresolution structure determination for integral membrane proteinsIMPsssNMR provides a unique platform to investigate protein dynamicsand functional studies of wide range of biomolecules in their supramolecular a ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. Targeted Nanotherapy to Donor Organ Endothelia Modulates Early Immune Responses and Protects Against Late Graft Failure

    SBC: ToleRaM NanoTech LLC            Topic: NIBIB

    ABSTRACT Transplantation is an accepted and highly successful therapy for end stage organ diseaseWhile success rates and survival have risen steadilydue largely to improved immunosuppression regimesthere is a growing appreciation that damage and inflammation that occur early in the life of the graftsignificantly impact chronic rejection and thus long term survivalCentral to these early event injur ...

    STTR Phase I 2018 Department of Health and Human Services
  5. Construction and testing of a rabbit cornea-equivalent for evaluation of chemical injury in vitro

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: NIEHS

    ABSTRACTWe propose combination of the rabbit cornea endothelial and epithelial cells with bioengineered scaffolds in cell culture well insertsThis technology could significantly reduce the use of rabbits for the Draize rabbit eye irritation assayThe barrier to commercialization is the lack of an effective method for storingbankingof living bioengineered cornea equivalentsWe will combine cell expan ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. Mitigating Injurious Falls in Older Adults Through Non-Injurious Fall and Gait Analysis From Floor Vibrations

    SBC: ADVANCED SMART SYSTEMS AND EVALUATION TECHNOLOGIES, LLC            Topic: NIA

    Project Summary and Abstract Falls are the leading cause of death due to injuryThis simple motion is so common thatof community dwelling older adultsandof long term care facilities will experience a fall in the coming yearThe risk of falling substantially increases for those having Alzheimer s disease and related dementiasand those with Parkinson s diseaseThe financial burden is significant with f ...

    STTR Phase I 2018 Department of Health and Human Services
  7. DMSO-free Cryopreservation of Bone Marrow-derived Stem Cells

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: NHLBI

    ABSTRACT Stem cell transplantation in the form of bone marrowperipheral blood or cord blood derived cells is commonly performed for reconstitution of the hematopoietic system of patients suffering from cancers and non malignant diseasesCurrent practice for cryopreservation of hematopoietic and mesenchymal stem cells is to employ the cell permeating cryoprotectant dimethylsulfoxideoften with an add ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. Automation of bioengineered epithelial construct cryopreservation

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: NIBIB

    ABSTRACT BSTRACT In an effort to reduce the use of animals for toxicity testingcompanies have developed bioengineered in vitro skin models to replace the Draize skin irritation testThe development of tissue models has been further pushed by the European Union that prohibited the use of animals infor collecting toxicological data on cosmetic ingredientsSupply of bioengineered tissues is a significa ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. eCPAT: Advancing public park information and technology resources to diverse audiences for healthy communities

    SBC: EnQ LLC            Topic: NCI

    Project Summary Abstract Quality parks provide numerous benefits to individuals and communitiesincluding health cost savings through physical activity and stress reliefincreased tax revenue via augmented property values and attracting businessesand positive social and environmental impacts through outcomes such as civic pride and pollution controlThe Community Park Audit ToolCPATprovides a compreh ...

    STTR Phase I 2018 Department of Health and Human Services
  10. Innovative therapy for accelerated recovery of decompression sickness patients

    SBC: SIL Technologies LLC            Topic: NHLBI

    PROJECT SUMMARY There are aroundemergency room admissions annually in the US due to scuba injuriesFrom thosearoundrelate to Decompression SicknessDCSa condition developed when nitrogen dissolved in blood and tissues at high pressure forms bubbles as pressure decreasesTreatment for DCS is recompression in hyperbaric chambersfollowing slow and controlled normalization of pressure conditionsEarly int ...

    SBIR Phase I 2018 Department of Health and Human Services
US Flag An Official Website of the United States Government