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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Developmentally Appropriate Technology for Science Assessment in Early Elementary Grades

    SBC: 3-C Institute for Social Development, Inc.            Topic: 99190018R0006

    In this project, researchers will develop a prototype of Science Quest, a tool to assess the science skills and understanding for students in grades 1 to 3. The prototype will deliver psychometrically validated assessment items in a game-like format. Educators will be able to assign and monitor completion of science assessments, view assessment results in real-time with reports at the individual a ...

    SBIR Phase I 2018 Department of EducationInstitute of Education Sciences
  2. Web Based Application to Promote Workplace Health Through Behavioral Design

    SBC: Innovation Research And Training, Inc.            Topic: ODCDC

    Healthy design features in a workplace can enable healthy eating and physical activitywhich are key behaviors in the prevention of obesity and other chronic diseasesAs of yetthere is no comprehensive webbased tool for designers and employers in different types of workplacesparticularly small business settingsto learn about and implement behavioral design strategies in the workplaceThe goal of this ...

    SBIR Phase I 2018 Department of Health and Human Services
  3. Topic 377: Enabling Clinical Decision Support for Guideline Based Cancer Symptom Management

    SBC: KLESIS, LLC            Topic: NCI

    The objective of this proposal is to develop an electronic, rule-based clinical decision support system (CDS-Sx) that leverages national clinical practice guidelines (CPGs) to improve cancer symptom management. Specific tasks that will be performed include: 1) create software-ready computable algorithms for managing cancer-related fatigue and constipation that have been vetted with diverse cancer ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Topic 374: Targeted and Sustained Release Microparticles for Colon Cancer Chemoprevention

    SBC: Zymeron Corporation            Topic: NCI

    Colorectal Cancer (CRC) is the third most common cancer both in men and women, as well as the second leading cause of cancer deaths with an estimated 135,430 new cases diagnosed and 50,260 deaths for 2017 in the United States. Given the limitations of screening tests and poor prognosis associated with advanced stage colorectal cancer, it would be of great interest in exploring chemoprevention stra ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a Designer Proline-rich antimicrobial peptide Chaperone protein inhibitor (DPC) for treating multi-drug resistant wound infections

    SBC: Arrevus, Inc.            Topic: NIAID

    Project SummaryOver $billion is spent annually in the US treating chronicnon healing woundsmany of which face lifethreatening complications due to infectionsWound infections are difficult to treat due to the frequency of antibiotic resistance as well as the formation of biofilmsa community of bacteria covered by an extracellular polymeric substanceBiofilm related infections can result in a substan ...

    STTR Phase I 2018 Department of Health and Human Services
  6. Innovative TME-specific Pro-CAR T-cells for Immunotherapy of Solid Tumors

    SBC: Panacise Bio, Inc.            Topic: 102

    Abstract This project seeks to develop the next generation pro CARs that are inactive in normal tissues but selectively activated in the tumor microenvironmentTMEThe project is based on our previous development of a novel class of chimeric antigen receptors on the basis of single domain antibody mimics that recognize ErbB family membersSDAErbBon the surface of cancer cellsWe propose two specific a ...

    STTR Phase I 2018 Department of Health and Human Services
  7. Improving Anticoagulation Monitoring in Pediatric Patients: Use of a Microfluidic Platform to Test Low Volume Blood Samples Obtained by Heel-Stick Collection

    SBC: Baebies, Inc.            Topic: NHLBI

    ABSTRACT Improving Anticoagulation Monitoring in Pediatric PatientsUse of a Microfluidic Platform to Test Low VolumeBlood Samples Obtained by Heel Stick CollectionFast Track SBIRThe goal of this Fast Track SBIR project is to develop a near patient platform for laboratory monitoring of anticoagulantsheparinheparinoidsand oral direct Factor Xa inhibitorsin children utilizing blood obtained from heel ...

    SBIR Phase I 2018 Department of Health and Human Services
  8. A Sensitive and Selective Microfluidic Nitrite Sensor

    SBC: CLINICAL SENSORS, INC.            Topic: 300

    PROJECT SUMMARYNitriteonce thought to simply be an intermediate of nitric oxideNOsynthesishas emerged as an important mediator of redox control and a major storage form of NO produced in the vasculatureIt has become clear that nitrite itself is involved in the regulation of vascular toneespecially in response to hypoxiaAssays to measure nitrite are employed across a broad range of clinical researc ...

    SBIR Phase I 2018 Department of Health and Human Services
  9. Reprogrammed T Cells to prevent graft versus host disease

    SBC: Element Genomics, Inc.            Topic: NIAID

    PROJECT SUMMARY ABSTRACT The objective of this proposal is to develop an efficient and robust method to epigenetically reprogram na ve human T cells into regulatory T cellsTregsthat can prevent graft versus host diseaseGvHDOur short term goal for Phase I of the STTR award is to demonstrate that we can epigenetically reprogram na ve T cells using CRISPR Casbased technology into immunosuppressive ce ...

    STTR Phase I 2018 Department of Health and Human Services
  10. A Low-Cost Platform for Routine High-Accuracy Sizing of Nucleic Acid Samples with 100 bp- 100 Mbp Dynamic Range

    SBC: Genturi Inc.            Topic: 172

    The goal of this project is to develop a microand nanofluidic DNA sizing platform with a sensitivityspeedand dynamic range that is unmatched by current sizing technologiesWe find that fluorescence burst analysis of individual DNA molecules transported through sub micrometer scale channels provides accurate and precise sizing of fragments betweenbp ands of MbpIn this singlemolecule sizing platformu ...

    SBIR Phase I 2018 Department of Health and Human Services
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