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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. sHLA Protein Chip

    SBC: GENOMICS USA, INC.            Topic: NIAID

    Abstract: “sHLA Protein Chip” The class I [A, B, C] and class II HLA proteins [DRB1, DQ, DP] comprise the heart of the inducible human immune system. For organ, marrow and stem cell transplantation, the development of serum-born antibodies against one or more of those many HLA proteins comprises the best and earliest test for transplant rejection. Because of the enormous medical importance of ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Aft Looking Spectrometer for Plume Characterization and Waking on Re-entry

    SBC: NANOHMICS INC            Topic: MDA16016

    Nanohmics proposes to develop a hyperspectral imager for aft-looking sensing of phenomenology associated with target vehicles.The payload is designed to operate with existing components and has no moving parts.The high spectral resolution will provide feedback for signature models and the spatial resolution will allow the spectral signatures to be associated with specific phenomena.Approved for Pu ...

    SBIR Phase II 2018 Department of DefenseMissile Defense Agency
  3. Advanced Rocket Trajectory Propagation Techniques

    SBC: NANOHMICS INC            Topic: MDA17T002

    High-fidelity trajectory propagators are fundamental to the simulation and analysis of launch vehicles, missiles, and satellites. Applications in fields ranging from missile threat analysis to flightpath optimization seek fast and accurate solutions to large numbers of trajectories in federated simulation environments. Due to their robustness, well-known properties, and straightforward implementat ...

    STTR Phase I 2018 Department of DefenseMissile Defense Agency
  4. Lightweight Structural Components of a Missile Body

    SBC: TEXAS RESEARCH INSTITUTE , AUSTIN, INC.            Topic: MDA17T004

    The Missile Defense Agency (MDA) has a need for weight-optimized solutions for future platforms of large missile structures. A significant weight reduction on these MDA platforms could increase maneuverability of the payload and allow the missile to launch additional kill vehicles. High temperature composite materials offer the means by which low cost and lighter weight missile structures can be a ...

    STTR Phase I 2018 Department of DefenseMissile Defense Agency
  5. Methodologies for Cost-Effective Measurement of Dynamic Material Properties or Characterization of Materials under Dynamic Loads

    SBC: PROTECTION ENGINEERING CONSULTANTS LLC            Topic: MDA16T003

    Explosions and high-velocity impacts can create strain rates on the order of 105 to 107 s-1. To simulate these events, first-principles codes require material models that are valid at these loading rates. Currently, the amount of test data, material models and material constants for this strain rate range is extremely limited, and an innovative and cost-effective laboratory test procedure is neede ...

    STTR Phase II 2018 Department of DefenseMissile Defense Agency
  6. Development of Taenia Solium Specific Aptamers for Diagnostic Assays

    SBC: LYNNTECH INC.            Topic: ODCDC

    The parasitic tapeworm Taenia solium causes two diseasestaeniasisadult worm in the intestineand cysticercosistissue infection by the cystwhich can lead to seizuresThe Tsolium life cycle involves both humans and pigshowever humans are the only definitive host for the adult Tsolium tapewormDiagnosing people infected with the adult worm is a critical step toward eliminating Tsolium althogetherHowever ...

    SBIR Phase I 2018 Department of Health and Human ServicesCenters for Disease Control and Prevention
  7. Topic 346: Targeted Radionuclide Therapy of Neuroendocrine Tumors Using 212Pb-octreotate Analogs

    SBC: RADIOMEDIX, INC.            Topic: NCI

    A peptide receptor radionuclide therapy (PRRT) using [177Lu]/[90Y]-labeled somatostatin analogs has been proven to induce objective response in 30-45% of patients with advanced/progressive neuroendocrine tumors (NETs). The complete response to beta-emitter PRRT is rare. This is due to the fact that NETs are diagnosed at late stage of disease; the NETs patients with remissions could develop resista ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Topic 379: Extensible and Scalable Platform for Data Integration from Wearable Sensors to Generate Novel Analytics for Cancer Patients

    SBC: Litmus Health, Inc.            Topic: NCI

    The longterm objective of the Litmus Health platform is to allow researchers and clinicians to use data on cancer patients from wearables/sensors and smartphones. Collecting real-time, high-quality data from patients will transform care and clinical trials. Automating data collection, storage, analysis, and interpretation of data will result in better measurement of signs and symptoms and improved ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Topic 372: Highly multiplexed selection of aptamers to hundreds of canine immunotherapy targets

    SBC: BASE PAIR BIOTECHNOLOGIES INC            Topic: NCI

    The preclinical development of cancer therapeutics, including the recent trend and focus on cancer immunotherapies, is evolving from the traditional use of mouse models to the use of other animal models including canine, rat, and minipig. Each of these non-mouse models carries its own advantages and abilities to increase the clinical relevance of the model as compared to mouse models. Yet, the wid ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. In situ assay for RNA decapping in tumors

    SBC: VIVID TECHNOLOGIES INC            Topic: 102

    In situ assay for RNA decapping in tumors Abstract This project aims to introduce a new histotechnology to assess tumor cell stress and cell death propensitywhich can be useful in evaluating cancer response to therapyThe adaptive response of tumor cells to stress and their survival in hostile environments are signaled by the levels of mRNA decayIncreased decay dumps important mRNAs and marks cells ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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