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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Resilient Wayside Structures to Reduce Severity of Passenger Equipment Collisions and Derailments

    SBC: PROTECTION ENGINEERING CONSULTANTS LLC            Topic: 171FR3

    Proposal title: Resilient Wayside Structures to Reduce Severity of Passenger Equipment Collisions and Derailments Additional passenger fatalities/injuries can occur during derailments involving interaction with wayside structures. Analogously, automobile fatalities often result from interaction of vehicles with roadside structures; personnel hazard reduction is a key design criterion for roadsid ...

    SBIR Phase II 2018 Department of Transportation
  2. Modified Partitioned Aquaculture System (P.A.S.) To Produce High Value Fish For Human Consumption

    SBC: J M MALONE & SON INC            Topic: 87

    The traditional fish farming industry in the U.S. is currently faced with rising costs, labor shortages, competition from lower cost imports, increasing environmental regulation, and decreasing water supplies. Sales of the domestic channel catfish industry alone fell from $423 million in 2011 to $301 million in 2014. Catfish acreage in Arkansas which totaled 30400 acres in 2007 (NASS 2008), was re ...

    SBIR Phase II 2018 Department of Agriculture
  3. Topic 346: Targeted Radionuclide Therapy of Neuroendocrine Tumors Using 212Pb-octreotate Analogs

    SBC: RADIOMEDIX, INC.            Topic: NCI

    A peptide receptor radionuclide therapy (PRRT) using [177Lu]/[90Y]-labeled somatostatin analogs has been proven to induce objective response in 30-45% of patients with advanced/progressive neuroendocrine tumors (NETs). The complete response to beta-emitter PRRT is rare. This is due to the fact that NETs are diagnosed at late stage of disease; the NETs patients with remissions could develop resista ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Development of an Oral Acidic Mammalian Chitinase Inhibitor to Treat Asthma

    SBC: ONCOARENDI THERAPEUTICS LLC            Topic: NHLBI

    Approximatelymillion Americans suffer from asthmawhich leads to aboutdeaths per yearand is responsible for estimated annual total direct and indirect costs of $billionDespite the existing treatments for asthmapredominantly combinations of inhaledagonists and corticosteroidsCSsthere remains a significant unmet medical need for new therapies which address two key issuesapproximatelyof patients are i ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. Additional costs related to formulation, chronic tox and general development of PTI-125

    SBC: PAIN THERAPEUTICS, INC.            Topic: NIA

    Project Summary Abstract PTIis a novel small molecule AD therapeutic candidate with a novel target and mechanism of actionPTIbinds and reverses an altered conformation of the scaffolding protein filamin AFLNAto prevent Aandapos s tight binding to and toxic signaling via thenicotinic acetylcholine receptornAChRas well as Aandapos s aberrant activation of toll like receptorTLRHenceby restoring FLNAa ...

    SBIR Phase II 2018 Department of Health and Human Services
  6. Real-Time Authentication to Counter Caller ID Spoofing

    SBC: Illuma Labs Inc.            Topic: HSB0171003

    Vulnerabilities in telecommunications channels are being exploited at alarming rates by malicious attackers to commit fraud, perpetrate scams, and organize data breaches. In addition to financial losses incurred by corporations and taxpayers, attacks against government agencies such as the DHS can severely compromise national security. A common element of these attacks is the attacker's ability to ...

    SBIR Phase II 2018 Department of Homeland Security
  7. A Layered Service Provider/Customer Approach to Call Spoofing

    SBC: SECURELOGIX CORPORATION            Topic: HSB0171003

    Our proposed solution is based upon three primary concepts. First, we define the Authentication Engine, which is a cloud-based service that is passed simple information about a call, masks the complexity of using a variety of techniques to detect spoofing or authenticate the caller, and returns a score and actionable category for a very wide variety of scenarios. Second, we are making heavy use of ...

    SBIR Phase II 2018 Department of Homeland Security
  8. Highly Efficient, Durable Regenerative Solid Oxide Stack

    SBC: Precision Combustion, Inc.            Topic: Z1

    Precision Combustion, Inc. (PCI) proposes to develop and advance a highly efficient regenerative solid oxide stack design. Novel structural elements allow reforming of regolith off-gases (e.g., methane and high hydrocarbons) within a solid oxide stack as well as efficient H2O/CO2 electrolysis, overcoming shortcomings of traditional approaches. The resulting design offers the potential for light-we ...

    SBIR Phase II 2018 National Aeronautics and Space Administration
  9. Rad-Hard Embedded Processing SIP

    SBC: Silicon Space Technology Corporation            Topic: S3

    VORAGO Technologies has created a product design and MIL-PRF-38534 qualification plan for a radiation-hardened miniaturized System-In-Package (SIP) that comprises an ARM® Cortex®-M0 microcontroller (VORAGO VA10820), a 16-channel 14-bit analog-to-digital converter (Cobham RHD5950) and a 2Mbit FRAM (Cypress CYRS15B102).  All the design work and planning has been put in place to produce ...

    SBIR Phase II 2018 National Aeronautics and Space Administration
  10. Flexible Integrated System Health Management for Sustainable Habitats using TEAMS

    SBC: QUALTECH SYSTEMS, INC.            Topic: H6

    QSI proposes to field a "Flexible" ISHM Solution for Sustainable Habitats utilizing the TEAMS Toolset and concomitant model-based and data-driven diagnostic/prognostic reasoning technologies to enable the habitat crew and ground support personnel to obtain crucial alerts that affect the operation of critical habitat subsystems. Automated health assessment, crew alerts and future degradat ...

    SBIR Phase II 2018 National Aeronautics and Space Administration

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